1-ACETYL-2,3,5-TRI-O-BENZOYL-B-L-RIBOFURANOSE

Uses

Product Name: 1-ACETYL-2,3,5-TRI-O-BENZOYL-B-L-RIBOFURANOSE
CAS No.: 3080-30-6
Chemical Name: 1-ACETYL-2,3,5-TRI-O-BENZOYL-B-L-RIBOFURANOSE
Synonyms: 1-acetyl-23,5-tri-O-benzoyl-Beta-L-ribose;β-L-Ribofuranose 1-Acetate 2,3,5-Tribenzoate;b-L-Ribofuranose, 1-acetate2,3,5-tribenzoate;1-ACETYL-2,3,5-TRI-O-BENZOYL-B-L-RIBOFURANOSE;β-L-Ribofuranose, 1-acetate 2,3,5-tribenzoate;1-ACETYL-2,3,5-TRI-O-BENZOYL-SS-L-RIBOFURANOSE;beta-L-Ribofuranose 1-Acetate 2,3,5-Tribenzoate;1-O-Acetyl-2,3,5-tri-O-benzoyl-b-L-ribofuranose;1-O-Acetyl-2,3,5-tribenzoyl-Beta-L-ribofuranose;1-O-Acetyl-2,3,5-tri-O-benzoyl-β-L-ribofuranose
CBNumber: CB3752386
Molecular Formula: C28H24O9
Formula Weight: 504.49
MOL File: 3080-30-6.mol

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1-ACETYL-2,3,5-TRI-O-BENZOYL-B-L-RIBOFURANOSE Property

Melting point:: 128.0 to 132.0 °C
Boiling point:: 621.0±55.0 °C(Predicted)
Density: 1.35±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: powder to crystal
color: White to Light yellow
InChIKey: GCZABPLTDYVJMP-BHUNBKLGNA-N
SMILES: O([C@H]1[C@@H](O[C@H](OC(=O)C)[C@H]1OC(C1C=CC=CC=1)=O)COC(C1C=CC=CC=1)=O)C(C1C=CC=CC=1)=O |&1:1,2,4,9,r|

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Safety

HS Code: 29400090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: R0080
Product name: β-L-Ribofuranose 1-Acetate 2,3,5-Tribenzoate
Purity: >98.0%(HPLC)
Packaging: 1g
Price: $120
Updated: 2025/07/31

TRC

Product number: A189403
Product name: β-L-Ribofuranose 1-Acetate 2,3,5-Tribenzoate
Packaging: 1g
Price: $130
Updated: 2021/12/16

Usbiological

Product number: 292300
Product name: 1-O-Acetyl-2,3,5-tri-O-benzoyl-b-L-ribofuranose
Packaging: 10g
Price: $531
Updated: 2021/12/16

Chem-Impex

Product number: 32357
Product name: β-L-Ribofuranose1-acetate2,3,5-tribenzoate,98%(HPLC)
Purity: 98%(HPLC)
Packaging: 1G
Price: $39.2
Updated: 2021/12/16

Chem-Impex

Product number: 32357
Product name: β-L-Ribofuranose1-acetate2,3,5-tribenzoate,98%(HPLC)
Purity: 98%(HPLC)
Packaging: 5G
Price: $100.8
Updated: 2021/12/16

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1-ACETYL-2,3,5-TRI-O-BENZOYL-B-L-RIBOFURANOSE Chemical Properties,Usage,Production

Uses

1-O-Acetyl-2,3,5-tri-O-benzoyl-?-L-ribofuranose is a useful research chemical.

Synthesis

108-24-7

69350-76-1

3080-30-6

The general procedure for the synthesis of (2R,3S,4S,5S)-2-acetoxy-5-((benzoyloxy)methyl)tetrahydrofuran-3,4-diyl dibenzoate from ethanoic anhydride and azacitidine impurity 27 was as follows: with reference to the method of Recondo and Rinderknecht, the compound was prepared from L-ribose by the preparation of 1-O-acetyl-2,3,5-tri-O- benzoyl-β-D-ribofuranose (1, R1 = Ac), or the compound was prepared from D-ribose (R2 = Bz). This was done as follows: the L-ribose (150 g, 1.0 mol) was dissolved in methanol (2.5 L) containing 1% HCl and after stirring for 2 h, the reaction mixture was neutralized with pyridine (250 mL). Subsequently, the mixture was concentrated under vacuum and the residue was dissolved in pyridine (1 L). Benzoyl chloride (385 mL, 3.3 mol) was added dropwise to this solution under cooling at 0°C. The reaction mixture was allowed to stand at room temperature overnight and then concentrated under vacuum at 35-40 °C. The residue was dissolved in ethyl acetate (1.5 L), and the organic phase was washed sequentially with cold water (2 x 0.5 L), 1N H2SO4 (3 x 0.5 mL), water (0.5 L), and saturated sodium bicarbonate solution (2 x 0.5 mL), and dried with magnesium sulfate. The dried organic phase was concentrated under vacuum to a syrupy consistency, which was dissolved in a mixture of glacial acetic acid (200 mL) and acetic anhydride (0.5 L). Concentrated sulfuric acid was added dropwise to this solution at 0°C. After completion of the reaction, the solidified product was filtered and washed sequentially with cold water (2×0.5 L), saturated sodium bicarbonate solution (2×0.5 L), cold water (2×0.5 L), and finally recrystallized from methanol to afford compound 1 (225 g, 45% yield) with a melting point of 124-125 °C. The 1H-NMR spectrum of the compound was consistent with that of the D-isomer.

References

[1] Patent: US2005/90660, 2005, A1. Location in patent: Page/Page column 35

1-ACETYL-2,3,5-TRI-O-BENZOYL-B-L-RIBOFURANOSE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-ACETYL-2,3,5-TRI-O-BENZOYL-B-L-RIBOFURANOSE Suppliers

China 84 Europe 1 Germany 2 India 6 Japan 4 United Kingdom 6 United States 8 Global 111

BOC Sciences

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View Lastest Price from 1-ACETYL-2,3,5-TRI-O-BENZOYL-B-L-RIBOFURANOSE manufacturers

Shenzhen Nexcon Pharmatechs Ltd.

Product: 1-ACETYL-2,3,5-TRI-O-BENZOYL-B-L-RIBOFURANOSE 3080-30-6
Price: US $0.00-0.00/F
Min. Order: 1F
Purity: 97%
Supply Ability: 2000
Release date: 2025-06-03

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 1-O-Acetyl-2,3,5-tri-O-benzoyl-beta-L-ribofuranose 3080-30-6
Price: US $0.00-0.00/g
Min. Order: 100g
Purity: 98%min
Supply Ability: 10000g
Release date: 2021-08-28

Shaanxi Dideu Medichem Co. Ltd

Product: 1-ACETYL-2,3,5-TRI-O-BENZOYL-B-L-RIBOFURANOSE 3080-30-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2024-08-04

3080-30-6, 1-ACETYL-2,3,5-TRI-O-BENZOYL-B-L-RIBOFURANOSERelated Search:

2,3-O-Isopropylidene-D-ribonic gamma-lactone 1,3,5-TRI-O-BENZOYL-ALPHA-L-RIBOFURANOSE 2,3-O-Isopropylidene-D-ribofuranoside 1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose 1-O-Methyl-2-deoxy-D-ribose (5-acetyloxy-3,4-dibenzoyloxy-oxolan-2-yl)methyl benzoate beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate 1-O-ACETYL-2,3,5-TRI-O-BENZOYL-B-D-RIBOFURANOSE Methyl-2-deoxy-beta-L-erythro-pentofuranose 2-Deoxy-beta-L-erythro-pentofuranose Methyl-2-deoxy-L-erythro-pentofuranose 1,3-Di-O-acetyl-2-deoxy-5-O-benzoyl-D-xylofuranose beta-D-Ribofuranose 1,2,3,5-tetraacetate 1-ACETYL-2,3,5-TRI-O-BENZOYL-B-L-RIBOFURANOSE 2-Deoxy-L-ribose 5-Deoxy-L-ribose 1,4-ANHYDRO-L-RIBITOL 1-O-Acetyl-2,3,5-tri-O-benzoyl-β-L-ribofuranose

1-O-ACETYL-2,3,5-TRI-O-BENZOYL-BETA-L-RIBOFURANOSE

1-O-Acetyl-2,3,5-tri-O-benzoyl-b-L-ribofuranose

1-ACETYL-2,3,5-TRI-O-BENZOYL-SS-L-RIBOFURANOSE

(2R,3S,4S,5S)-2-acetoxy-5-(benzoyloxymethyl)tetrahydrofuran-3,4-diyl dibenzoate

beta-L-Ribofuranose 1-Acetate 2,3,5-Tribenzoate

[5-acetyloxy-4-(benzoyloxy)-2-(benzoyloxymethyl)oxolan-3-yl] benzoate

[5-acetyloxy-4-phenylcarbonyloxy-2-(phenylcarbonyloxymethyl)oxolan-3-yl] benzoate

1-ACETYL-2,3,5-TRI-O-BENZOYL-BETA-L-RIBOFURANOSE

1-ACETYL-2,3,5-TRI-O-BENZOYL-B-L-RIBOFURANOSE

benzoic acid [5-acetoxy-4-(benzoyloxy)-2-(benzoyloxymethyl)tetrahydrofuran-3-yl] ester

β-L-Ribofuranose 1-Acetate 2,3,5-Tribenzoate

-<small>L</small>-Ribofuranose 1-Acetate 2,3,5-Tribenzoate

1-acetyl-23,5-tri-O-benzoyl-Beta-L-ribose

1-O-Acetyl-2,3,5-tribenzoyl-Beta-L-ribofuranose

benzoic acid (5-acetyloxy-3,4-dibenzoyloxy-2-oxolanyl)methyl ester

[(2S,3S,4R,5R)-5-acetyloxy-3,4-dibenzoyloxyoxolan-2-yl]methyl benzoate

β-L-Ribofuranose 1-Acetate 2,3,5-Tribenzoate &gt

1-O-Acetyl-2,3,5-tri-O-benzoyl-β-L(-)-ribofuranos

β-L-Ribofuranose, 1-acetate 2,3,5-tribenzoate

1-O-Acetyl-2,3,5-tri-O-benzoyl-β-L-ribofuranose

1-ACETYL-2,3,5-TRI-O-BENZOYL-B-L-RIBOFURANOSE USP/EP/BP

b-L-Ribofuranose, 1-acetate2,3,5-tribenzoate

1-O-Acetyl-2,3,5-Tri-O-Benzoyl-b-L-Ribofuranose extrapure, 98%

Ribofuranose, 1-acetate 2,3,5-tribenzoate (6CI, 7CI)

2-Acetoxy-5-[(benzoyloxy)methyl]tetrahydrofuran-3,4-diyl (2R,3S,4S,5S)-Dibenzoate

3080-30-6