2-Deoxy-L-ribose
- Product Name
- 2-Deoxy-L-ribose
- CAS No.
- 18546-37-7
- Chemical Name
- 2-Deoxy-L-ribose
- Synonyms
- -ribose;2-Deoxy-L;L-2-Deoxyribose;2-DEOXY-L-RIBOSE;Xylose Impurity 19;2-DEOXY-L-RIBOSE 99%;2-Deoxy-L-ribose,99%;2-Deoxy-L-ribose ,98%;Brivudine Impurity 22;L-ERYTHRO-PENTOFURANOSE
- CBNumber
- CB6704755
- Molecular Formula
- C5H10O4
- Formula Weight
- 134.13
- MOL File
- 18546-37-7.mol
2-Deoxy-L-ribose Property
- Melting point:
- 69-72°C
- alpha
- 57 º (c=0.9 H2O after 24h)
- Boiling point:
- 167.23°C (rough estimate)
- Density
- 1.0590 (rough estimate)
- refractive index
- 1.4050 (estimate)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Methanol (Slightly), Water (Slightly)
- form
- Solid
- pka
- 13.58±0.20(Predicted)
- color
- Light Yellow to Pale Beige
- optical activity
- [α]/D 54.0±2.0°, 24 hr, c = 1 in H2O
- CAS DataBase Reference
- 18546-37-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 24/25-37/39-36-26
- HS Code
- 29329990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 75617
- Product name
- 2-Deoxy-L-ribose
- Purity
- ≥97.0% (TLC)
- Packaging
- 5g
- Price
- $306
- Updated
- 2024/03/01
- Product number
- 75617
- Product name
- 2-Deoxy-L-ribose
- Purity
- ≥97.0% (TLC)
- Packaging
- 1g
- Price
- $62.7
- Updated
- 2023/06/20
- Product number
- D252050
- Product name
- 2-Deoxy-L-ribose
- Packaging
- 5G
- Price
- $150
- Updated
- 2021/12/16
- Product number
- 292960
- Product name
- 2-Deoxy-L-ribose
- Packaging
- 5g
- Price
- $319
- Updated
- 2021/12/16
- Product number
- 162247
- Product name
- 2-Deoxy-L-erythro-pentopyranose
- Packaging
- 0.500g
- Price
- $320
- Updated
- 2021/12/16
2-Deoxy-L-ribose Chemical Properties,Usage,Production
Chemical Properties
white to light beige crystalline powder
Uses
2-Deoxy-L-ribose is an isomer of 2-Deoxy-D-ribose (D252000) which induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione.
Definition
ChEBI: 2-deoxy-L-arabinose is a deoxypentose. It is functionally related to a L-arabinose.
Production Methods
The provides the synthetic process of 2-Deoxy-L-ribose comprising the steps of; (A) protection step in which aldehyde group of 2-deoxy-D-ribose is protected in the form of acetal. 2-deoxy-l-O-alkyl-D-ribopyranoside is prepared by the reaction of 2-deoxy-D-ribose with alcohol in the presence of acid; (B) activation step in which 3 -and 4-OH groups of 2-deoxy-D-ribose are activated. 2-deoxy-l-O-alkyl- 3,4-di-(alkanesulfonyl)-D-ribose or 2-deoxy-1-O-alkyl-3,4-di-(arylsulfonyl)-D-ribose is prepared by reaction of the above 2-deoxy-l-O-alkyl-D-ribose with organic sulfonylhalide for activation of 3- and 4-OH; (C) inversion step in which stereochemistry of 3- and 4-OH groups is changed. Reaction of the above 2-deoxy-l- O-alkyl-3,4-di-(alkanesulfonyl)-D-ribose or 2-deoxy-l-O-alkyl-3,4-di-(arylsulfonyl)- D-ribose with a metal salt of organic acid leads to 2-deoxy-L-ribose derivatives of which stereochemistry of 3- and 4-OH is different from the corresponding 2-deoxy-D- ribose derivatives; (D) deprotection step in which 2-deoxy-L-ribose is prepared by consecutive reactions of the step (C) products with acid and base.
Purification Methods
Crystallise 2-deoxy--L-ribose from diethyl ether. It can also be purified by dissolving the ribose (7.3g) in EtOAc (3L) by reflux, decanting from any insoluble mate
2-Deoxy-L-ribose Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Deoxy-L-ribose manufacturers
- Product
- 2-Deoxy-L-ribose 18546-37-7
- Price
- US $0.00/Kg/Bag
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 100kgs
- Release date
- 2021-09-16
- Product
- 2-Deoxy-L-ribose 18546-37-7
- Price
- US $60.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000tons
- Release date
- 2023-08-16
- Product
- 2-Deoxy-L-ribose 18546-37-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-29