PHENDIMETRAZINE BITARTRATE
- Product Name
- PHENDIMETRAZINE BITARTRATE
- CAS No.
- 50-58-8
- Chemical Name
- PHENDIMETRAZINE BITARTRATE
- Synonyms
- sprx;metra;adipost;melfiat;plegine;prelu-2;Alphazine;phendimetrazinetartrate;PHENDIMETRAXINE TARTRATE;PHENDIMETRAZINE BITARTRATE
- CBNumber
- CB3757053
- Molecular Formula
- C20H29NO13
- Formula Weight
- 491.44
- MOL File
- 50-58-8.mol
PHENDIMETRAZINE BITARTRATE Property
- Melting point:
- 182 °C
- storage temp.
- -20°C
- form
- A solid
Safety
- RIDADR
- UN 1992 6.1(3) / PGIII
- HS Code
- 2934910000
- Toxicity
- LD50 intraperitoneal in mouse: 210mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- API0003805
- Product name
- PHENDIMETRAZINE BITARTRATE
- Purity
- 95.00%
- Packaging
- 100G
- Price
- $4244.63
- Updated
- 2021/12/16
- Product number
- MT-57833
- Product name
- Phendimetrazinebitartrate
- Purity
- 98%
- Packaging
- 50ml
- Price
- $630
- Updated
- 2021/12/16
- Product number
- P-7804
- Product name
- PhendimetrazineTartrate
- Packaging
- 25mg
- Price
- $1100
- Updated
- 2021/12/16
PHENDIMETRAZINE BITARTRATE Chemical Properties,Usage,Production
Originator
Plegine, Ayerst, US ,1961
Uses
Appetite suppressant (systemic).
Manufacturing Process
A mixture of 61 grams 1-phenyl-1-oxo-2-(N-methyl-N-ethanolamino)-propane hydrochloride and 100 cc 98-100% formic acid was refluxed at the boiling point at atmospheric pressure for 45 minutes on an oil bath. Thereafter, the oil bath temperature was increased to 180°C and as much of the excess unreacted formic acid as possible was distilled off. A vigorous evolution of carbon dioxide developed during the distillation, which ceased after approximately 45 additional minutes. The honey-yellow syrup which remained as the distillation residue was worked up by admixing it with about six volumes of water and adjusting the aqueous mixture to alkaline reaction with concentrated sodium hydroxide. An oily phase separated out which was extracted with ether. The ether extract was washed with water and dried over potassium carbonate. The solvent was distilled off and the distillation residue was fractionally distilled in vacuo. The base boils at 132°-133°C at 12 mm. The yield was 93% of theory. Reaction with tartaric acid gave the final product.
The starting material is produced by reacting propiophenone with bromine and then reacting the α-bromopropiophenone produced with 2methylaminomethanol.
brand name
Bontril (Mallinckrodt); Bontril (Valeant); Melfiat (Numark).
Therapeutic Function
Antiobesity
General Description
The optically pure compound phendimetrazine tartrate,(2S,3S)-3,4-dimethyl-2-phenylmorpholine-L-(+)-tartrate(Plegine), is considered an effective anorexiant that is lessabuse prone than amphetamine. The stereochemistry of(+)phendimetrazine is as shown.
Safety Profile
Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. An antihistamine. When heated to decomposition it emits toxic fumes of NOx.
PHENDIMETRAZINE BITARTRATE Preparation Products And Raw materials
Raw materials
Preparation Products
PHENDIMETRAZINE BITARTRATE Suppliers
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- zhangsn@titansci.com
- Country
- China
- ProdList
- 14113
- Advantage
- 59
- Tel
- 86-21-63210123
- Fax
- 86-21-63290778 86-21-63218885
- sj_scrc@sinopharm.com
- Country
- China
- ProdList
- 9823
- Advantage
- 79
- Tel
- +86 (21) 61124340
- Fax
- +86 (21) 6129-4103
- Country
- China
- ProdList
- 9767
- Advantage
- 58
- Tel
- Fax
- -
- xg01_gj@163.com
- Country
- China
- ProdList
- 9503
- Advantage
- 50
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131981
- Advantage
- 58
- Tel
- 13382066392
- Country
- CHINA
- ProdList
- 4880
- Advantage
- 58
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 19892
- Advantage
- 58
- Tel
- +1-5166625404
- Fax
- 1-516-927-0118
- Info@alfa-chemistry.com
- Country
- United States
- ProdList
- 21317
- Advantage
- 58
- Tel
- 0571-85134551
- Fax
- 008657185134895
- info@afinechem.com
- Country
- CHINA
- ProdList
- 15377
- Advantage
- 58
- Tel
- +86-023-61398051 +8613650506873
- sales@chemdad.com
- Country
- China
- ProdList
- 39916
- Advantage
- 58
View Lastest Price from PHENDIMETRAZINE BITARTRATE manufacturers
- Product
- PHENDIMETRAZINE BITARTRATE 50-58-8
- Price
- US $1.00/KG
- Min. Order
- 1G
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-08-20