ChemicalBook > CAS DataBase List > 2-Chloro-5-trifluoromethylbenzaldehyde

2-Chloro-5-trifluoromethylbenzaldehyde

Product Name
2-Chloro-5-trifluoromethylbenzaldehyde
CAS No.
82386-89-8
Chemical Name
2-Chloro-5-trifluoromethylbenzaldehyde
Synonyms
TIMTEC-BB SBB003466;2-Chloro-5-trifluoromethylb;4-Chloro-3-formylbenzotrifluoride;2-CHLORO-5-(TRIFLUOROMETHYL)BENZALDEHYDE;2-Chloro-5-(trifluoromethyl)benzaldehyde98%;Benzaldehyde, 2-chloro-5-(trifluoromethyl)-;2-Chloro-5-(trifluoromethyl)benzaldehyde >2-Chloro-5-(trifluoromethyl)benzaldehyde, 97+%;2-Chloro-5-(trifluoroMethyl)benzaldehyde, 95+%;4-Chloro-3-formylbenzotrifluoride, 6-Chloro-alpha,alpha,alpha-trifluoro-m-tolualdehyde
CBNumber
CB3759178
Molecular Formula
C8H4ClF3O
Formula Weight
208.57
MOL File
82386-89-8.mol
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2-Chloro-5-trifluoromethylbenzaldehyde Property

Boiling point:
42-44 °C1.5 mm Hg(lit.)
Density 
1.435 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.488(lit.)
Flash point:
193 °F
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
clear liquid
color 
White to Yellow to Green
Specific Gravity
1.435
Sensitive 
Air Sensitive
InChIKey
OZZOJJJYKYKBNH-UHFFFAOYSA-N
CAS DataBase Reference
82386-89-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
RIDADR 
NA 1993 / PGIII
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29130000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
376825
Product name
2-Chloro-5-(trifluoromethyl)benzaldehyde
Purity
98%
Packaging
5g
Price
$59
Updated
2025/07/31
TCI Chemical
Product number
C2047
Product name
2-Chloro-5-(trifluoromethyl)benzaldehyde
Purity
>95.0%(GC)
Packaging
5g
Price
$62
Updated
2025/07/31
TCI Chemical
Product number
C2047
Product name
2-Chloro-5-(trifluoromethyl)benzaldehyde
Purity
>95.0%(GC)
Packaging
25g
Price
$259
Updated
2025/07/31
TRC
Product number
C596553
Product name
2-Chloro-5-(trifluoromethyl)benzaldehyde
Packaging
50mg
Price
$60
Updated
2021/12/16
Oakwood
Product number
007805
Product name
2-Chloro-5-(trifluoromethyl)benzaldehyde
Purity
99%
Packaging
1g
Price
$9
Updated
2021/12/16
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2-Chloro-5-trifluoromethylbenzaldehyde Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid

Uses

2-Chloro-5-(trifluoromethyl)benzaldehyde may be used as reactant in the three-component reaction of 2-halogenated aromatic aldehydes, 1H-benzo[d]imidazol-5-amine and cyclohexane-1,3-diones to afford imidazoquinolinoacridinone derivatives. It may be used in the gas-phase chemical derivatization of poly(tetrafluoroethylene) and poly(ethylene terephthalate) using gas plasma.

Synthesis

64372-62-9

82386-89-8

General procedure for the synthesis of 2-chloro-5-trifluoromethylbenzaldehyde from 2-chloro-5-trifluoromethylbenzyl alcohol: 2-chloro-5-trifluoromethylbenzyl alcohol (5.0 mmol), copper acetate (Cu(OAc)2, 9.1 mg, 0.05 mmol), and 2,2,6,6-tetramethylpiperidinium-1-oxyl radical (TEMPO, 7.8 mg, 0.05 mmol ) in a solvent mixture of acetonitrile (CH3CN, 5 mL) and water (H2O, 10 mL) was stirred at room temperature for the reaction. The reaction process was monitored by thin-layer chromatography (TLC) and the eluent was petroleum ether/ethyl acetate (4:1). After completion of the reaction, dichloromethane (10 mL) was added to the reaction mixture for extraction. The organic phase was separated and the aqueous phase was extracted twice more with dichloromethane (10 mL x 2). All organic phases were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to obtain the crude product. The crude product was purified by column chromatography with the eluent of petroleum ether/ethyl acetate (10:1) to obtain the target product 2-chloro-5-trifluoromethylbenzaldehyde.

References

[1] Tetrahedron Letters, 2014, vol. 55, # 10, p. 1677 - 1681
[2] Collection of Czechoslovak Chemical Communications, 1982, vol. 47, # 3, p. 967 - 983
[3] Collection of Czechoslovak Chemical Communications, 1982, vol. 47, # 3, p. 967 - 983
[4] Collection of Czechoslovak Chemical Communications, 1982, vol. 47, # 3, p. 967 - 983

2-Chloro-5-trifluoromethylbenzaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Chloro-5-trifluoromethylbenzaldehyde manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Chloro-5-trifluoromethylbenzaldehyde 82386-89-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-11-08
Shaanxi Dideu Medichem Co. Ltd
Product
2-Chloro-5-trifluoromethylbenzaldehyde 82386-89-8
Price
US $0.00-0.00/KG
Min. Order
10mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-15
Career Henan Chemical Co
Product
2-Chloro-5-trifluoromethylbenzaldehyde 82386-89-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-06-28

82386-89-8, 2-Chloro-5-trifluoromethylbenzaldehydeRelated Search:


  • TIMTEC-BB SBB003466
  • 2-CHLORO-5-(TRIFLUOROMETHYL)BENZALDEHYDE
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  • 2-Chloro-5-(trifluoromethyl)benzaldehyde, 97+%
  • 2-Chloro-5-(trifluoromethyl)benzaldehyde98%
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  • 4-Chloro-3-formylbenzotrifluoride
  • 2-Chloro-5-(trifluoroMethyl)benzaldehyde, 95+%
  • 2-Chloro-5-(trifluoromethyl)benzaldehyde &gt
  • Benzaldehyde, 2-chloro-5-(trifluoromethyl)-
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