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1-Chlorocarbonyl-1-methylethyl acetate

Product Name
1-Chlorocarbonyl-1-methylethyl acetate
CAS No.
40635-66-3
Chemical Name
1-Chlorocarbonyl-1-methylethyl acetate
Synonyms
2-ACETOXYISOBUTYRYL CHLORIDE;2-Acetoxy-2-methylpropanoyl chloride;SKL1299;1-Chlorocarbonyl-1-m;2-acetyl chloride oxy iso;2-acetoxyisobutyl chloride;2-ACETOXYLISOBUTYRYL BROMIDE;2-acetoxyisobutyroyl chloride;2-Acetoxyisobutyryl Chloride >ALPHA-ACETOXY-ISOBUTYRYL CHLORIDE
CBNumber
CB3774199
Molecular Formula
C6H9ClO3
Formula Weight
164.59
MOL File
40635-66-3.mol
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1-Chlorocarbonyl-1-methylethyl acetate Property

Boiling point:
55-56 °C/6 mmHg (lit.)
Density 
1.136 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.428(lit.)
Flash point:
155 °F
storage temp. 
Inert atmosphere,2-8°C
solubility 
Acetonitrile (Slightly), Chloroform (Slightly)
form 
clear liquid
color 
Colorless to Light yellow
Sensitive 
Moisture Sensitive
BRN 
507772
InChI
1S/C6H9ClO3/c1-4(8)10-6(2,3)5(7)9/h1-3H3
InChIKey
RBTCRFLJLUNCLL-UHFFFAOYSA-N
SMILES
CC(=O)OC(C)(C)C(Cl)=O
CAS DataBase Reference
40635-66-3(CAS DataBase Reference)
NIST Chemistry Reference
2-Acetoxyisobutyryl chloride(40635-66-3)
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Safety

Hazard Codes 
C
Risk Statements 
14-34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
10-21
HazardClass 
8
PackingGroup 
III
HS Code 
29189990
Storage Class
8A - Combustible corrosive hazardous materials
Hazard Classifications
Skin Corr. 1B
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
326178
Product name
1-Chlorocarbonyl-1-methylethyl acetate
Purity
95%
Packaging
5g
Price
$45.88
Updated
2025/07/31
Sigma-Aldrich
Product number
326178
Product name
1-Chlorocarbonyl-1-methylethyl acetate
Purity
95%
Packaging
25g
Price
$116
Updated
2025/07/31
TCI Chemical
Product number
A1120
Product name
2-Acetoxyisobutyryl Chloride
Purity
>97.0%(T)
Packaging
5g
Price
$49
Updated
2025/07/31
TCI Chemical
Product number
A1120
Product name
2-Acetoxyisobutyryl Chloride
Purity
>97.0%(T)
Packaging
25g
Price
$143
Updated
2025/07/31
Usbiological
Product number
414831
Product name
2-Acetoxyisobutyryl chloride
Packaging
2.5g
Price
$305
Updated
2021/12/16
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1-Chlorocarbonyl-1-methylethyl acetate Chemical Properties,Usage,Production

Uses

1-Chlorocarbonyl-1-methylethyl acetate was used in preparation of α,γ-dichloro alditols.

Preparation

1-Chlorocarbonyl-1-methylethyl acetate can be prepared by the acylation of 2-hydroxyisobutyric acid (Acetyl Chloride, Acetic Acid) followed by reaction with Thionyl Chloride.

General Description

Reaction of 1-chlorocarbonyl-1-methylethyl acetate with 1-aryl ethylene glycols to yield trans chlorohydrin acetates was reported.

storage

1-Chlorocarbonyl-1-methylethyl acetate is corrosive and a lachrymator and should be handled accordingly.

1-Chlorocarbonyl-1-methylethyl acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Chlorocarbonyl-1-methylethyl acetate Suppliers

J & K SCIENTIFIC LTD.
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18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
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Alfa Aesar
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400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
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China
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
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China
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Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
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Changzhou Huanling Chemical Co., Ltd.
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0519-89803565 13776850645
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0519-89803575
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China
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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China
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XiaoGan ShenYuan ChemPharm co,ltd
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15527621225
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1791901229@qq.com
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China
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Shandong Xiya Chemical Co., Ltd
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13355009207 13355009207
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0539-6365991
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3007715519@qq.com
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China
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Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
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info@syntechem.com
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China
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12984
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Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
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86-21-63290778 86-21-63218885
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sj_scrc@sinopharm.com
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China
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View Lastest Price from 1-Chlorocarbonyl-1-methylethyl acetate manufacturers

Career Henan Chemical Co
Product
1-Chlorocarbonyl-1-methylethyl acetate 40635-66-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-12-18

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