ChemicalBook > CAS DataBase List > Phenol Red

Phenol Red

Product Name
Phenol Red
CAS No.
143-74-8
Chemical Name
Phenol Red
Synonyms
PR;PHENOLSULFONPHTHALEIN;phenolsulphonphthalein;A-HYDROXY-A A-BIS(P-HYDROXYPHENYL)-O-TOLUENESULFONIC ACID G-SULTONE;PRGR;NR3C3;Phenolrde;Phenol re;PHENOL RED;fenolipuna
CBNumber
CB3780134
Molecular Formula
C19H14O5S
Formula Weight
354.38
MOL File
143-74-8.mol
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Phenol Red Property

Melting point:
>300 °C
Boiling point:
>300°C
Density 
1.445 Mg m-3
refractive index 
1.5300 (estimate)
Flash point:
>300°C
storage temp. 
no restrictions.
solubility 
1 M NaOH: soluble1mg/mL
form 
Solid
pka
7.9(at 25℃)
color 
Red
PH Range
6.6(YELLOW)-8.0(RED)
PH
6.8～8.4
Odor
Odorless
Water Solubility 
0.77 g/L
λmax
557nm, 558nm, 360nm, 423nm, 433nm
Merck 
14,7247
BRN 
326470
Major Application
Display device, sol-gel matrix, photoreceptors, fuel cells, waveguides, paints, detergents, cosmetics, antiperspirant composition, diapers, screening bacteria, detecting viable cells, diagnosis of urogenital ureaplasmosis, treatment of pathogen infections, amyloid-associated diseases, glaucoma, pulmonary hypertension, asthma, chronic obstructive pulmonary disease, erectile dysfunction, Raynaud’s syndrome, heparin overdose, vulvodynia, wound healing, psychoactive drugs, evaluating dental caries activity
InChIKey
BELBBZDIHDAJOR-UHFFFAOYSA-N
LogP
3.020
CAS DataBase Reference
143-74-8(CAS DataBase Reference)
EPA Substance Registry System
Phenol Red (143-74-8)
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Safety

Hazard Codes 
Xi,C
Risk Statements 
36/37/38-34
Safety Statements 
37/39-26-45-36/37/39-27
WGK Germany 
3
RTECS 
SJ7490000
TSCA 
Yes
HS Code 
29349990
Toxicity
LD50 orl-rat: >600 mg/kg CTOXAO 4(2),185,71
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
114529
Product name
Phenol Red
Purity
ACS reagent
Packaging
5g
Price
$29.4
Updated
2024/03/01
Sigma-Aldrich
Product number
114529
Product name
Phenol Red
Purity
ACS reagent
Packaging
25g
Price
$85.4
Updated
2024/03/01
Sigma-Aldrich
Product number
1.59375
Product name
Phenol red
Purity
(phenolsulfonphthalein) Reag. Ph Eur
Packaging
1g
Price
$817
Updated
2024/03/01
Sigma-Aldrich
Product number
1.07241
Product name
Phenol red
Purity
indicator ACS
Packaging
5G
Price
$117
Updated
2024/03/01
Sigma-Aldrich
Product number
1.59375
Product name
Phenol red
Purity
(phenolsulfonphthalein) Reag. Ph Eur
Packaging
100g
Price
$8170
Updated
2024/03/01
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Phenol Red Chemical Properties,Usage,Production

Description

Phenol red belongs to the class of triphenylmethane dyes and is widely used in the textile industry.

Chemical Properties

dark red powder

Uses

As indicator in 0.02-0.05% alcohol solution. pH 6.8 yellow, 8.4 red.

Uses

Phenol red is used as a non absorbed marker in gravimetric method. It is a pH indicator used in cell biology laboratories and in home swimming pool test kits. It is used to check the kidney function based on the excreted phenol red by colorimetric method.

Uses

Phenol red solution acts as a pH indicator for the culture medium.

Application

Phenol red solution has been used:
As a tracer dye for microinjection of zebrafish eggs.
As a component of the mMW medium for preparation of mouse embryos.
In the preparation of versene-ethylenediamine tetraacetic acid (EDTA) solution.

Preparation

Phenol red is prepared in Dulbecco′s Phosphate Buffered Saline.

Definition

ChEBI: 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups. A pH indicator changing colour from yellow below pH 6.8 to bright pink above pH 8.2, it is commonly used as an indicator in cell cultures and in home swimming pool test kits. It is also used in the (now infrequently performed) phenolsulfonphthalein (PSP) test for estimation of overall blood flow through the kidney.

Biochem/physiol Actions

Phenol Red is a pH indicator which changes color from yellow to red.

Safety Profile

Moderately toxic by ingestion and intravenous routes. Mutation data reported. When heated to decomposition it emits toxicvapors of SOx.

Enzyme inhibitor

This pH-indicating dye (FW = 354.38 g/mol; CAS 143-74-8; pKa = 7.9; yellow < pH 6.8; red > pH 8.4), also known as phenolsulfonphthalein and sulfophthalein, is a diagnostic aid for evaluating renal function. A typical stock indicator solution is 0.1 g phenol red in 28.2 mL 10 mM NaOH and 221.8 mL water. Target(s): aldehyde reductase; glutaminase; gglutamyl transpeptidase; glutathione S-transferase; 4- methyleneglutaminase; phosphate uptake; thromboxane A2/prostaglandin H2 receptor; and thyroglobulin iodination.

Phenol Red Preparation Products And Raw materials

Raw materials

2-Sulfobenzoic anhydride Zinc chloride

Preparation Products

Bromophenol Blue
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View Lastest Price from Phenol Red manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Phenol Red 143-74-8
Price
US $75.00-25.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-27
Apeloa production Co.,Limited
Product
Phenol red 143-74-8
Price
US $0.50/g
Min. Order
1g
Purity
99%
Supply Ability
100000
Release date
2024-06-07
Hebei Chuanghai Biotechnology Co,.LTD
Product
Phenolsulfonephthalein 143-74-8
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kg
Release date
2024-08-22

143-74-8, Phenol RedRelated Search:

Phenol Chlorosulfonyl isocyanate Cyclopentane Cresol Red 2-Aminophenol SODIUM PHENOLATE TRIHYDRATE Methylcyclopentane 4-Aminophenol Potassium phthalimide Chlorine dioxide 3-Aminophenol Quartz 2-Phenylphenol Bromocyclopentane Amidosulfuron Carbon dioxide Sulfosulfuron Rutile

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