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MURISTERONE A

Product Name
MURISTERONE A
CAS No.
38778-30-2
Chemical Name
MURISTERONE A
Synonyms
MURA;Muristerone;MURISTERONE A;Ecdysonic sterol;MURISTERONE A(P);MURISTERONE A USP/EP/BP;MURISTERONE A, IPOMOEA SPP;5B, 7-CHOLESTENE-2B,3B,5A,11A,14,20,22-HEPTOL-6-ONE;2B,3B,5A,11A,14,20,22-HEPTAHYDROXY-5B-7-CHOLESTEN-6-ONE;2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one
CBNumber
CB3781616
Molecular Formula
C27H44O8
Formula Weight
496.63
MOL File
38778-30-2.mol
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MURISTERONE A Property

Boiling point:
707.2±60.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Soluble in DMSO
form 
solid
pka
11.78±0.70(Predicted)
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
11741
Product name
Muristerone A
Purity
≥95%
Packaging
250μg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
11741
Product name
Muristerone A
Purity
≥95%
Packaging
1mg
Price
$155
Updated
2024/03/01
TRC
Product number
M732780
Product name
MuristeroneA
Packaging
1mg
Price
$205
Updated
2021/12/16
Usbiological
Product number
255918
Product name
Muristerone A
Packaging
1mg
Price
$480
Updated
2021/12/16
Usbiological
Product number
045051
Product name
Muristerone A
Packaging
250ug
Price
$289
Updated
2021/12/16
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MURISTERONE A Chemical Properties,Usage,Production

Description

Muristerone A is a natural analog of 20-hydroxyecdysone . It is an agonist of the ecdysteroid receptor (Kd = 1 nM), a nuclear receptor that heterodimerizes with a retinoid X receptor ortholog and regulates arthropod development. Muristerone A is used as an agonist in ecdysone-inducible gene expression systems in mammalian cells. However, it inhibits apoptosis in the human colon carcinoma cell line RKO by inducing the upregulation of Bcl-xL, suggesting limitations in its use in certain types of studies.

Uses

Muristerone A, an ecdysteroid, is widely used for the induction of ecdysteroid-dependent transcription in mammalian cells.

Biological Activity

Ecdysone analog that acts as an inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals. Stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells.

storage

+4°C

MURISTERONE A Preparation Products And Raw materials

Raw materials

Preparation Products

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MURISTERONE A Suppliers

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38778-30-2, MURISTERONE ARelated Search:

3,5-Dimethyl-2-cyclohexen-1-one Celery ketone L-Menthol Isophorone 1-HYDROXY-3-CYCLOHEXENE 2-Octyl-1-dodecanol cis-9-Tricosene RICINOLEYL ALCOHOL 2-Methyl-3-buten-2-ol 3,7-DIMETHYL-1-OCTEN-3-OL 1-Decen-3-ol 5-METHYL-2-HEPTEN-4-ONE Dihydromyrcenol cis-1,2-Cyclohexanediol (-)-NEOMENTHOL 1-ACETYLCYCLOHEXANOL MURISTERONE A 2-HEPTANONE，5-(HYDROXYMETHYL)

  • 2B,3B,5A,11A,14,20,22-HEPTAHYDROXY-5B-7-CHOLESTEN-6-ONE
  • 2BETA,3BETA,5ALPHA,11ALPHA,14,20,22-HEPTAHYDROXY-5BETA,7-CHOLESTEN-6-ONE
  • 2BETA,3BETA,5BETA,11ALPHA,14ALPHA,20R,22R-HEPTAHYDROXYCHOLEST-7-EN-6-ONE
  • 5B, 7-CHOLESTENE-2B,3B,5A,11A,14,20,22-HEPTOL-6-ONE
  • 5BETA,7-CHOLESTENE-2BETA,3BETA,5ALPHA,11ALPHA,14,20,22-HEPTOL-6-ONE
  • MurA, 2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one
  • (22R)-2β,3β,5,11α,14,20,22-Heptahydroxy-5β-cholest-7-en-6-one
  • Ecdysonic sterol
  • Muristerone
  • Cholest-7-en-6-one, 2,3,5,11,14,20,22-heptahydroxy-, (2beta,3beta,5beta,11alpha,22R)-
  • (2β,3β,5β,11α,22R)-2,3,5,11,14,20,22-Heptahydroxycholest-7-en-6-one
  • MURISTERONE A(P)
  • (2beta,3beta,5beta,11alpha,22R)-2,3,5,11,14,20,22-Heptahydroxy-cholest-7-en-6-one
  • MURISTERONE A
  • MURISTERONE A, IPOMOEA SPP
  • MURA
  • 2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one
  • MURISTERONE A USP/EP/BP
  • Cholest-7-en-6-one, 2,3,5,11,14,20,22-heptahydroxy-, (2β,3β,5β,11α,22R)-
  • 38778-30-2
  • BioChemical
  • Apoptosis and Cell Cycle
  • Cell Biology
  • Apoptosis Inducers
  • Cell Signaling and Neuroscience
  • Miscellaneous Natural Products