MURISTERONE A
- Product Name
- MURISTERONE A
- CAS No.
- 38778-30-2
- Chemical Name
- MURISTERONE A
- Synonyms
- MURA;Muristerone;MURISTERONE A;Ecdysonic sterol;MURISTERONE A(P);MURISTERONE A USP/EP/BP;MURISTERONE A, IPOMOEA SPP;5B, 7-CHOLESTENE-2B,3B,5A,11A,14,20,22-HEPTOL-6-ONE;2B,3B,5A,11A,14,20,22-HEPTAHYDROXY-5B-7-CHOLESTEN-6-ONE;2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one
- CBNumber
- CB3781616
- Molecular Formula
- C27H44O8
- Formula Weight
- 496.63
- MOL File
- 38778-30-2.mol
MURISTERONE A Property
- Boiling point:
- 707.2±60.0 °C(Predicted)
- Density
- 1.33±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- Soluble in DMSO
- form
- solid
- pka
- 11.78±0.70(Predicted)
- color
- white
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- 11741
- Product name
- Muristerone A
- Purity
- ≥95%
- Packaging
- 250μg
- Price
- $57
- Updated
- 2024/03/01
- Product number
- 11741
- Product name
- Muristerone A
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $155
- Updated
- 2024/03/01
- Product number
- M732780
- Product name
- MuristeroneA
- Packaging
- 1mg
- Price
- $205
- Updated
- 2021/12/16
- Product number
- 255918
- Product name
- Muristerone A
- Packaging
- 1mg
- Price
- $480
- Updated
- 2021/12/16
- Product number
- 045051
- Product name
- Muristerone A
- Packaging
- 250ug
- Price
- $289
- Updated
- 2021/12/16
MURISTERONE A Chemical Properties,Usage,Production
Description
Muristerone A is a natural analog of 20-hydroxyecdysone . It is an agonist of the ecdysteroid receptor (Kd = 1 nM), a nuclear receptor that heterodimerizes with a retinoid X receptor ortholog and regulates arthropod development. Muristerone A is used as an agonist in ecdysone-inducible gene expression systems in mammalian cells. However, it inhibits apoptosis in the human colon carcinoma cell line RKO by inducing the upregulation of Bcl-xL, suggesting limitations in its use in certain types of studies.
Uses
Muristerone A, an ecdysteroid, is widely used for the induction of ecdysteroid-dependent transcription in mammalian cells.
Biological Activity
Ecdysone analog that acts as an inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals. Stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells.
storage
+4°C