Pacmilimab

Product Name: Pacmilimab
CAS No.: 2145091-51-4
Chemical Name: Pacmilimab
Synonyms: Pacmilimab;Pacmilimab (anti-PD-L1);Research Grade Pacmilimab;Research Grade Pacmilimab(DHJ70105)
CBNumber: CB38081183
Formula Weight: 0
MOL File: Mol file

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Pacmilimab Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Pacmilimab Chemical Properties,Usage,Production

Uses

Pacmilimab (CX-072) is a potent PD-L1 inhibitor. Pacmilimab shows antitumor activity[1].

in vivo

Pacmilimab induces antitumor responses comparable to those of the same dose of the parental antibody in mice bearing MC38 tumors^[1].
Pacmilimab accumulates in murine PD-L1-expressing tumors with minimal uptake in peripheral, non-cancerous lymphoid tissue, consistent with limited uptake in non-tumor PD-L1-expressing tissues and protection against autoimmunity^[1].

References

[1] Naing A, et al. CX-072 (pacmilimab), a Probody ? PD-L1 inhibitor, in advanced or recurrent solid tumors (PROCLAIM-CX-072): an open-label dose-finding and first-in-human study. J Immunother Cancer. 2021 Jul;9(7):e002447. DOI:10.1136/jitc-2021-002447

Pacmilimab Preparation Products And Raw materials

Raw materials

Preparation Products

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Pacmilimab Suppliers

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2145091-51-4, PacmilimabRelated Search:

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Pacmilimab

Research Grade Pacmilimab(DHJ70105)

Research Grade Pacmilimab

Pacmilimab (anti-PD-L1)

2145091-51-4