Synthesis
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4-BROMO-BENZO[B]THIOPHENE

Synthesis
Product Name
4-BROMO-BENZO[B]THIOPHENE
CAS No.
5118-13-8
Chemical Name
4-BROMO-BENZO[B]THIOPHENE
Synonyms
4-Bromobenzothiophene;4-BROMO-1-BENZOTHIOPHENE;4-bromo-thiophene;4-Bromothianaphthene;5-cyanobenzothiophene;Bromobenzo[b]thiophene;4-BROMO-BENZO[B]THIOPHENE;Brexpiprazole intermdiate;Benzo[b]thiophene,4-broMo-;CAS5118-13-8 4-BROMO-BENZO[B]THIOPHENE
CBNumber
CB3813658
Molecular Formula
C8H5BrS
Formula Weight
213.09
MOL File
5118-13-8.mol
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4-BROMO-BENZO[B]THIOPHENE Property

Boiling point:
144 °C(Press: 20 Torr)
Density 
1.649±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
form 
solid
color 
White to off-white
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Safety

Hazard Codes 
Xi
Hazard Note 
Irritant
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
B680503
Product name
4-Bromo-benzo[b]thiophene
Packaging
1g
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
122176
Product name
4-Bromobenzothiophene
Purity
90+%
Packaging
25g
Price
$84
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB57657
Product name
4-Bromobenzo[b]thiophene
Packaging
1g
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB57657
Product name
4-Bromobenzo[b]thiophene
Packaging
2g
Price
$150
Updated
2021/12/16
SynQuest Laboratories
Product number
5H66-9-X5
Product name
4-Bromobenzo[b]thiophene
Packaging
25g
Price
$160
Updated
2021/12/16
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4-BROMO-BENZO[B]THIOPHENE Chemical Properties,Usage,Production

Synthesis

The traditional synthesis method is to take 2-bromo-6-fluorobenzaldehyde as a raw material, cyclize the raw material with mercaptoacetic acid in a DMF solvent to obtain 4-chlorobenzo [b] thiophene-2-carboxylic acid, and then decarboxylate the product at a high temperature in a quinoline/copper powder system to obtain the 4-chlorobenzo [b] thiophene. 

Uses

4-bromobenzo [b] thiophene is an important intermediate in the drug ipiprazole for the treatment of schizophrenia.

4-BROMO-BENZO[B]THIOPHENE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-BROMO-BENZO[B]THIOPHENE Suppliers

Chengdu Aofan Pharmtech Co.,Ltd
Tel
13038283958
Email
2865097598@qq.com
Country
China
ProdList
105
Advantage
55
Nanjing CoreTech Biomedical Co,.Ltd
Tel
025-52880806 13770327895
Fax
86-025-52880803
Email
API@core-tech.com.cn
Country
China
ProdList
82
Advantage
58
Bayee Biotech (Anqing) Co., Ltd.
Tel
0556-5032306 18917961636
Fax
+86-556-5032307
Email
wtx@bayeebio.com
Country
China
ProdList
253
Advantage
61
Jinan Lide Pharmaceutical Technology Co., Ltd.
Tel
0531-68654990 18560195202
Fax
053168654990
Email
leadgxm@leadchem.net
Country
China
ProdList
153
Advantage
58
TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.
Tel
022-60182192,1339732154 18722583064
Fax
86-22-60979672
Email
marketing@pharmacn.com
Country
China
ProdList
112
Advantage
61
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35906
Advantage
56
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9555
Advantage
66
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070 13913916777;
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17839
Advantage
64
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View Lastest Price from 4-BROMO-BENZO[B]THIOPHENE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4-BROMO-BENZO[B]THIOPHENE 5118-13-8
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-04-26
WUHAN FORTUNA CHEMICAL CO., LTD
Product
4-Bromobenzo[b]thiophene 5118-13-8
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-06
Changzhou Rokechem Technology Co., Ltd.
Product
4-bromo-1-benzothiophene 5118-13-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%min HPLC
Supply Ability
1-10000KGS
Release date
2022-09-19

5118-13-8, 4-BROMO-BENZO[B]THIOPHENERelated Search:


  • 4-BROMO-BENZO[B]THIOPHENE
  • 4-Bromobenzothiophene
  • 4-BROMO-1-BENZOTHIOPHENE
  • 4-Bromothianaphthene
  • 5-cyanobenzothiophene
  • 4-bromo-thiophene
  • Benzo[b]thiophene,4-broMo-
  • 4-Bromo-1-benzothiophene, 4-Bromothianaphthene
  • 4-BROMO-BENZO[B]THIOPHENE ISO 9001:2015 REACH
  • Brexpiprazole intermdiate
  • CAS5118-13-8 4-BROMO-BENZO[B]THIOPHENE
  • Bromobenzo[b]thiophene
  • Brexpiprazole Impurity 13 4-Bromo benzo[b]thiophene
  • 5118-13-8
  • Benzothiophene
  • Halogenated
  • Organohalides