ChemicalBook > CAS DataBase List > 1-(2-Furoyl)piperazine

1-(2-Furoyl)piperazine

Product Name
1-(2-Furoyl)piperazine
CAS No.
40172-95-0
Chemical Name
1-(2-Furoyl)piperazine
Synonyms
AKOS BB/0087;AKOS B003992;AKOS BBS-00003689;BIO-FARMA BF003584;TIMTEC-BB SBB003747;RARECHEM AH CK 0108;N-Furoyl piperazine;2-furoic piperazide;Terazosin Impurity10;2-(2-FUROYL)PIPERAZINE
CBNumber
CB3853599
Molecular Formula
C9H12N2O2
Formula Weight
180.2
MOL File
40172-95-0.mol
More
Less

1-(2-Furoyl)piperazine Property

Melting point:
67-70 °C(lit.)
Boiling point:
137-140°C 0,1mm
Density 
1.1819 (rough estimate)
refractive index 
1.5373 (estimate)
Flash point:
>230 °F
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Chloroform, Methanol (Slightly)
pka
8.37±0.10(Predicted)
color 
White to Pale Yellow
Sensitive 
Hygroscopic
BRN 
880196
Stability:
Very Hygroscopic
CAS DataBase Reference
40172-95-0(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
3
F 
10-34
HazardClass 
IRRITANT
HS Code 
29339900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR3100
Product name
Prazosin Related Compound D
Purity
certified reference material, pharmaceutical secondary standard
Packaging
50MG
Price
$485
Updated
2024/03/01
Sigma-Aldrich
Product number
558966
Product name
1-(2-Furoyl)piperazine
Purity
97%
Packaging
25g
Price
$133
Updated
2023/06/20
Sigma-Aldrich
Product number
Y0000623
Product name
Terazosin impurity L
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0000623
Price
$149
Updated
2023/01/07
Alfa Aesar
Product number
A16773
Product name
1-(2-Furoyl)piperazine, 98%
Packaging
25g
Price
$65.5
Updated
2021/12/16
Alfa Aesar
Product number
A16773
Product name
1-(2-Furoyl)piperazine, 98%
Packaging
100g
Price
$188
Updated
2021/12/16
More
Less

1-(2-Furoyl)piperazine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow solid

Uses

2-Furanyl-1-piperazinylmethanone (Terazosin EP Impurity L) was utilized in the fragment-based design of symmetrical bis-benzimidazole as inhibitors of R67 dihydrofolate reductase.

Uses

1-(2-Furoyl)piperazine may be used to synthesize:

  • 2-[4-(2-furoyl) piperazin-1-yl]-4-amino-6-benzyloxy-7-methoxyquinazoline hydrochloride monohydrate
  • 2-[4-(2-furoyl)piperazin-1-yl]-4-amino-7-benzyloxy-6-methoxyquinazoline hydrochloride monohydrate
  • 4-amino-2-[4-(2-furoyl)piperazin-1-yl]-quinazoline hydrochloride
  • 6,7-dimethoxy-2-[4-(2-furoyl)-piperazin-1-yl]quinazoline-4-one hydrate
  • 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(2-furoyl)-piperazine hydrogen oxalate
  • 1-(3,4-dichlorobenzyl)-4-(2-furoyl)-piperazine hydrogen oxalate
  • 4-(9-fluorenyl)-1-(2-furoyl)piperazine
  • 2-[4-(2-furoyl)piperazin-1-yl]-benzimidazole hydrochloride hydrate

Uses

2-Furanyl-1-piperazinylmethanone was utilized in the fragment-based design of symmetrical bis-benzimidazole as inhibitors of R67 dihydrofolate reductase.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 20, p. 146, 1977 DOI: 10.1021/jm00211a031

1-(2-Furoyl)piperazine Preparation Products And Raw materials

Raw materials

2-Furoic acid Toluene Di-tert-butyl dicarbonate Triethylamine Piperazine Dichloromethane Sodium hydroxide Thionyl chloride

Preparation Products

Prazosin
More
Less

1-(2-Furoyl)piperazine Suppliers

Belgium 3 Canada 3 China 128 Europe 2 France 2 Germany 11 India 35 Japan 3 Slovakia 1 South Korea 1 Switzerland 2 The Netherlands 1 United Kingdom 16 United States 41 Global 249
Creasyn Finechem(Tianjin) Co., Ltd.
Tel
022-022-83946278 13820372920
Fax
022-83945176
Email
sales@creasyn.com
Country
China
ProdList
994
Advantage
68
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Suzhou Highfine Biotech Co., Ltd
Tel
0512-68311833 13962195826
Fax
0512-68417696
Email
wuhao@highfine.com
Country
China
ProdList
498
Advantage
75
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35906
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12458
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11605
Advantage
64
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5700
Advantage
66
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
Fax
qq：2817624287
Email
lyh_antaeus@163.com
Country
China
ProdList
9352
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
Shanghai Hao Yun Chemical Science Co.,Ltd.
Tel
021-68367562 15002147577;
Fax
021-68369562
Email
sales@haoyunchem.com
Country
China
ProdList
462
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17982
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9636
Advantage
58
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4951
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10287
Advantage
55
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5947
Advantage
50
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9503
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Shangdong Youbang Biochemical Technology Co.,LTD.
Tel
15098208899
Fax
0530-7159266
Email
3368029756@qq.com
Country
China
ProdList
292
Advantage
58
Wuhan Chemwish Technology Co.， Ltd
Tel
027-67849912
Fax
027-87531808
Email
sales@chemwish.com
Country
China
ProdList
9150
Advantage
60
Qingxian Creasyn Pharmaceutical Technology Co., Ltd.
Tel
022-83945173 18622315263
Fax
QQ1559208715
Email
export@creasyn.com
Country
China
ProdList
466
Advantage
55
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10457
Advantage
58
Shanghai Qiao Chemical Science Co., Ltd
Tel
021-58892003
Email
info@qiaochem.com
Country
China
ProdList
5881
Advantage
65
Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14623
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Guangzhou Jhd Chemical Reagent Co., Ltd.
Tel
020-84383047
Fax
020-84380294
Email
sales@jhd.com.cn
Country
China
ProdList
9190
Advantage
65
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19806
Advantage
60
Shanghai BaiShun Biological Technology Co., Ltd
Tel
021-37581181
Fax
021-57456066
Email
sales@chem-mall.com
Country
China
ProdList
10335
Advantage
58
Capot Chemical Co.,Ltd.
Tel
571-85586718 +8613336195806
Fax
+86-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
29797
Advantage
60
Aikon International Limited
Tel
025-66113011 18112977050
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
16028
Advantage
58
Conier Chem & Pharma Limited
Tel
13368167990
Email
sales@conier.com
Country
China
ProdList
2809
Advantage
58
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 18521078705
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
20043
Advantage
58
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17997
Advantage
58
Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.
Tel
027-51831887 15337167856
Fax
027-51837635 QQ1165326703
Email
hubeixinyuanshun@163.com
Country
China
ProdList
10305
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
400-400-400-9004166 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52712
Advantage
58
yxinchem
Tel
+86-0710-4323688 +86-18071785587
Fax
15502706050
Email
market@yxinchem.com
Country
China
ProdList
1022
Advantage
58
Chengdu MassCale Pharmaceutical Co., Ltd.
Tel
028-84552636 18084815636
Email
chensfsc@126.com
Country
China
ProdList
1448
Advantage
58
Finetech Industry Limited
Tel
+86-27-87465837 +8618971612321
Fax
86 27 87772287
Email
info@finetechnology-ind.com
Country
China
ProdList
9635
Advantage
58
More
Less

View Lastest Price from 1-(2-Furoyl)piperazine manufacturers

Career Henan Chemical Co
Product
1-(2-Furoyl)piperazine 40172-95-0
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200kg
Release date
2019-08-30

40172-95-0, 1-(2-Furoyl)piperazineRelated Search:

N-Aminoethylpiperazine 2-Ethylhexyl ferulate Piperazine Piperacillin 1-(Tetrahydro-2-Furoyl)Piperazine,TerazosinHcl,,1-(TETRAHYDRO-2-FUROYL)PIPERAZINE,N-(TETRAHYDRO-2-FUROYL)-PIPERAZINE 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl)piperazine monohydrochloride Terazosin impurity 2-Piperazine-4-amino-6,7-dimethoxyquinazoline (R)-Terazosin 2,2'-(1,4-Piperazinediyl)bis[6,7-diMethoxy-4-quinazolinaMine] 1-[4-(4-AMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl]-5-hydroxy-1-pentanone 6,7-DiMethoxy-2-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)quinazolin-4(1H)-one Terazosin EP IMpurity D [4-(4-AMino-7-hydroxy-6-Methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)Methanone NSC 351869 [4-(4-AMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl][(5S)-tetrahydro-5-Methyl-2-furanyl]Methanone Terazosin hydrochloride dihydrate Terazosin IMpurity J

  • BIO-FARMA BF003584
  • (FURAN-2-YL)(PIPERAZIN-1-YL)METHANONE
  • 1-(2-FURANYLCARBONYL)-PIPERAZINE
  • 1-(2-FUROYL)PIPERAZINE
  • AKOS BBS-00003689
  • AKOS B003992
  • AKOS BB/0087
  • N-(2-FUROYL)PIPERAZINE
  • RARECHEM AH CK 0108
  • TIMTEC-BB SBB003747
  • 2-(2-FUROYL)PIPERAZINE
  • N-Furoyl piperazine
  • 1-(2-FUROYL)-PIPERAZINE 97%
  • 2-furoic piperazide
  • 1-(2-Furoyl)piperazine,98%
  • Piperazine, 1-(2-furanylcarbonyl)-
  • (2-Furyl)(piperazino) ketone
  • Piperazino 2-furyl ketone
  • Piperazino(2-furanyl) ketone
  • Piperazino(2-furyl) ketone
  • 1-(2-Furoyl)-piperazine ,97%
  • Prazosin EP IMpurity D
  • 2-Furanyl-1-piperazinylmethanone
  • 1-(2-Furoyl)piperazine96%
  • N-(2-Furoyl) piperazine 1-(2-Furoyl) piperazine
  • Terazosin EP Impurity L
  • Terazosin Impurity 12(Terazosin EP Impurity L)
  • Terazosin Impurity10
  • Prazosin Impurity 4(Prazosin EP Impurity D)
  • 1-(furan-2-carbonyl)piperazine
  • Terazosin EP Impurity L (Prazosin EP Impurity D)
  • Prazosin EP Impurity D (Terazosin EP Impurity L)
  • Methanone, 2-furanyl-1-piperazinyl-
  • 40172-95-0 1-(2-Furoyl)piperazine
  • Terazosin Hydrochloride Dihydrate EP Impurity L
  • Prazosin Hydrochloride Impurity D
  • Terazosin Hydrochloride Dihydrate Impurity L
  • 40172-95-0
  • Heterocyclic Building Blocks
  • Piperazines
  • Building Blocks
  • BUILDING BLOCKS
  • API intermediates
  • Piperidines, Piperidones, Piperazines