Propiverine hydrochloride

Product Name: Propiverine hydrochloride
CAS No.: 54556-98-8
Chemical Name: Propiverine hydrochloride
Synonyms: Bup-4;Urecure;Noraguard;Nsc172140;Pollarine;mictonorm;Uronaverine;Mictonetten;PROPIVERINE HCL;Yansuan Bingpaiweilin
CBNumber: CB3855472
Molecular Formula: C23H30ClNO3
Formula Weight: 403.94
MOL File: 54556-98-8.mol

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Propiverine hydrochloride Property

Melting point:: 224-226°C
storage temp.: 2-8°C
solubility: H2O: soluble5mg/mL, clear (warmed)
form: powder
color: white to beige
CAS DataBase Reference: 54556-98-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 37/38-41
Safety Statements: 26-39
WGK Germany: 3
RTECS: AH3297000
Toxicity: LD50 in male, female mice, male, female rats (mg/kg): 36, 36, 22, 25 i.v.; 223, 283, 1632, 1411 s.c.; 410, 323, 1000, 1092 orally (Yamashita)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0602
Product name: Propiverine hydrochloride
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $37.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0602
Product name: Propiverine hydrochloride
Purity: ≥98% (HPLC)
Packaging: 100mg
Price: $193
Updated: 2024/03/01

TRC

Product number: P828000
Product name: Propiverine hydrochloride
Packaging: 250mg
Price: $225
Updated: 2021/12/16

TRC

Product number: P828000
Product name: Propiverine hydrochloride
Packaging: 100mg
Price: $110
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 13193
Product name: PropiverineHCl
Packaging: 100mg
Price: $845
Updated: 2021/12/16

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Propiverine hydrochloride Chemical Properties,Usage,Production

Description

Propiverine hydrochloride is a new urological agent developed for pollakuria and aconuresis. It appears to exhibit anticholinergic properties and in animal experiments inhibited KCl induced contractions in the bladder and ileum.

Chemical Properties

Off-White Solid

Originator

Apogepha (Germany)

Uses

Propiverine is used in treatment of urinary incontinence. Propiverine is an anticholinergic.

Definition

ChEBI: Propiverine hydrochloride is a diarylmethane.

brand name

Mictonorm; Mictonetten

General Description

Propiverine hydrochloride drug is a tertiary amine with spasmolytic and analgesic properties. This drug exerts neurotropic and musculotropic effects on the urinary bladder and smooth muscles. Propiverine hydrochloride has a half-life of 20 hours.

Biochem/physiol Actions

Propiverine is an antimuscarinic drug used for the treatment of overactive blaqdder and urinary incontinence. Propiverine and/or its metabolites also have calcium channel blocking properties in addition to antimuscarinic activity, which may contribute to the clinical activity.

Clinical Use

Treatment of urinary frequency, urgency and incontinence
Neurogenic bladder instability

Drug interactions

Potentially hazardous interactions with other drugs
Anti-arrhythmics: increased risk of antimuscarinic side effects with disopyramide.

Metabolism

Propiverine is extensively metabolised by intestinal and hepatic enzymes. Four metabolites were identified in urine; two of them are pharmacologically active and may contribute to the therapeutic efficacy.
Propiverine and its metabolites are excreted in the urine, bile and faeces.

Propiverine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Propiverine hydrochloride Suppliers

Canada 1 China 143 Europe 1 Germany 1 India 7 United Kingdom 5 United States 23 Global 181

LGM Pharma

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TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

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CacheSyn Inc.

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Medical Isotopes

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View Lastest Price from Propiverine hydrochloride manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Propiverine hydrochloride 54556-98-8
Price: US $1.00/g
Min. Order: 1g
Purity: ≥98%
Supply Ability: 1kg/month
Release date: 2021-06-16

Hebei Weibang Biotechnology Co., Ltd

Product: Propiverine hydrochloride 54556-98-8
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100 mt
Release date: 2024-11-20

Baoji Guokang Bio-Technology Co., Ltd.

Product: Propiverine hydrochloride 54556-98-8
Price: US $1142.00/Kg/Bag
Min. Order: 100g
Purity: 99%
Supply Ability: 100kg
Release date: 2021-06-04

54556-98-8, Propiverine hydrochlorideRelated Search:

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PROPIVERINE HCL

propiverine hydrochloride

PROPIVERINE HYDROCHLORRIDE

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1-Methyl-4-piperidyldiphenylpropoxyacetateHCl

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Bup-4

Noraguard

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Nsc172140

Mictonetten

Pollarine

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mictonorm

Propiverine Hydrochloride RS

Propiverine hydrochloride USP/EP/BP

Yansuan Bingpaiweilin

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54556-98-8

C23H29NO3ClH

C23H29NO3HCl

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