Thioproperazine

Product Name: Thioproperazine
CAS No.: 316-81-4
Chemical Name: Thioproperazine
Synonyms: Vontil;Megeptil;Mazeptyl;Majeptyl;Cephalmin;Sulfenazin;hioproperazine;thioproperazine;N'-(4-chlorophenyl)-N,N-dimethylcarbamimidic acid methyl ester;N,N-Dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-sulfonamide
CBNumber: CB3912908
Molecular Formula: C22H30N4O2S2
Formula Weight: 446.63
MOL File: 316-81-4.mol

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Thioproperazine Property

Melting point:: 140°
Boiling point:: 612.2±65.0 °C(Predicted)
Density: 1.1476 (rough estimate)
refractive index: 1.6200 (estimate)
storage temp.: Sealed in dry,Room Temperature
form: Solid
pka: 7.65±0.10(Predicted)
color: Light yellow to yellow
NIST Chemistry Reference: Thioproperazine(316-81-4)

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Safety

Toxicity: LD50 oral in mouse: 830mg/kg

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PH003261
Product name: N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine-2-sulfonamide
Purity: AldrichCPR
Packaging: 1MG
Price: $172
Updated: 2023/06/20

Crysdot

Product number: CD11146489
Product name: Thioproperazine
Purity: 97%
Packaging: 100mg
Price: $416
Updated: 2021/12/16

Crysdot

Product number: CD11146489
Product name: Thioproperazine
Purity: 97%
Packaging: 250mg
Price: $665
Updated: 2021/12/16

Crysdot

Product number: CD11146489
Product name: Thioproperazine
Purity: 97%
Packaging: 1g
Price: $1664
Updated: 2021/12/16

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Thioproperazine Chemical Properties,Usage,Production

Originator

Majeptil,Specia,France,1960

Definition

ChEBI: A phenothiazine derivative in which the phenothiazine tricycle has a dimethylaminosulfonyl substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at N-10.

Manufacturing Process

A solution of 3-dimethylsulfamoylphenthiazine (5 g) in anhydrous xylene (100 cc) is heated under reflux for 1 hour with sodamide (0.67 g). 3-(4-methyl-1- piperazinyl)-1-chloropropane (3.2 g) in solution in anhydrous xylene (20 cc) is added and the mixture heated under reflux for 5 hours. After treatment of the reaction products, a crude oily base (2.5 g) is obtained after treatment. By the addition of a solution of fumaric acid in ethanol to an ethanolic solution of the base, 3-dimethylsulfamoyl-10-(3-41-methyl-11-piperazinylpropyl)- phenthiazinediacid fumarate (2.6 g) is obtained, melting point 182°C. The base recrystallized from ethyl acetate melts at about 140°C.

Therapeutic Function

Neuroleptic, Antiemetic

Thioproperazine Preparation Products And Raw materials

Raw materials

Preparation Products

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Thioproperazine Suppliers

China 23 India 2 South Korea 1 United States 3 USA 1 Global 30

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18207
Advantage: 66

ShangHai Movin Pharmaceutical Co., Ltd.

Tel: 13681854265
Email: info@moenpharm.com
Country: China
ProdList: 508
Advantage: 55

Shanghai Zhixin Chemical Technology Co., Ltd.

Tel: 021-60441077 18701958033
Fax: 021-60441077
Email: shzxchem@163.com
Country: China
ProdList: 592
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Aikon International Limited

Tel: 025-66113011 18112977050
Fax: (5)02557626880
Email: cb6@aikonchem.com
Country: China
ProdList: 15494
Advantage: 58

Zhengzhou Ruke Biological Co., Ltd.

Tel: 15981811963
Fax: QQ：1410472904
Email: 1410472904@qq.com
Country: China
ProdList: 5825
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30240
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49374
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

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View Lastest Price from Thioproperazine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Thioproperazine 316-81-4
Price: US $1.00/G
Min. Order: 1G
Purity: 98%
Supply Ability: 100G
Release date: 2024-05-22

316-81-4, ThioproperazineRelated Search:

N,N-Dimethylformamide Cyclopropanesulfonamide Phenothiazine p-Toluenesulfonamide Dimethyl ether Propyl gallate Imipramine hydrochloride Dimethyl sulfide 4,4'-Diaminodiphenylsulfone Benzenesulfonamide Dimethyl fumarate Terazosin hydrochloride Thioridazine Dimethyl sulfoxide ETHANE Propyl butyrate DIOXOPROMETHAZINE HCL CHLORPROPAMIDE

thioproperazine

N,N-Dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-sulfonamide

10H-Phenothiazine-2-sulfonamide, N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-

Cephalmin

Phenothiazine-2-sulfonamide, N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-

Sulfenazin

N'-(4-chlorophenyl)-N,N-dimethylcarbamimidic acid methyl ester

hioproperazine

Majeptyl

Mazeptyl

Megeptil

Vontil

316-81-4

C22H30N4O2S2