4-O-(Carboxymethyl)rifamycin

Product Name: 4-O-(Carboxymethyl)rifamycin
CAS No.: 13929-35-6
Chemical Name: 4-O-(Carboxymethyl)rifamycin
Synonyms: C01848;Nacimycin;Nancimycin;Rifomycin B;NCI-145-604;Rifamycin B CRS;Rifamycin impurity A;Rifaximin EP Impurity B;Rifamycin EP Impurity A;Rifaximin impurity B (EP)
CBNumber: CB3913884
Molecular Formula: C39H49NO14
Formula Weight: 755.8
MOL File: 13929-35-6.mol

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4-O-(Carboxymethyl)rifamycin Property

Melting point:: 300° (dec 160-164°)
alpha: D20 -11° (methanol)
Boiling point:: 730.16°C (rough estimate)
Density: 1.2421 (rough estimate)
refractive index: 1.5350 (estimate)
solubility: DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated)
pka: 2.69±0.10(Predicted)
BRN: 604953
Stability:: Unstable in solution

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Safety

Toxicity: LD50 in mice (mg/kg): 2040 i.v., >3000 i.p., s.c., and orally (Sensi, 1964)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: R0900000
Product name: Rifamycin B
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: r0900000
Price: $220
Updated: 2024/03/01

TRC

Product number: R508170
Product name: Rifamycin B
Packaging: 50mg
Price: $160
Updated: 2021/12/16

TRC

Product number: R508170
Product name: Rifamycin B
Packaging: 500mg
Price: $1295
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0009903
Product name: RIFAMYCIN B
Purity: 95.00%
Packaging: 500MG
Price: $1871.1
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0009903
Product name: RIFAMYCIN B
Purity: 95.00%
Packaging: 50MG
Price: $315
Updated: 2021/12/16

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4-O-(Carboxymethyl)rifamycin Chemical Properties,Usage,Production

Uses

Rifamycin B (Rifaximin EP Impurity B) is a Rifamycin (R508200) derivative as antibacterial agent.

Uses

A Rifamycin (R508200) derivative as antibacterial agent.

Definition

ChEBI: Rifamycin B is a carboxylic acid, an acetate ester, an organic heterotetracyclic compound and a member of rifamycins. It is a conjugate acid of a rifamycin B(2-).

Purification Methods

Rifamycin B forms yellow needles from *C6H6. Its solubilities are: H2O (0,027%), MeOH (2.62%) and EtOH (0.44%). It has UV max at 223, 304 and 245nm (A 1cm 555, 275 and 220). [Oppolzer & Prelog Helv Chim Acta 56 2287 1973, Oppolzer et al. Experientia 20 336 1964, X-ray: Brufani et al. Experientia 20 339 1964.]

4-O-(Carboxymethyl)rifamycin Preparation Products And Raw materials

Raw materials

Preparation Products

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13929-35-6, 4-O-(Carboxymethyl)rifamycinRelated Search:

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Rifamycin impurity A

Rifaximin EP Impurity B

Rifaximin impurity B (EP)

Rifaximin Impurity 2 (Rifaximin EP Impurity B)

Rifamycin, 4-O-(carboxymethyl)-

4-O-(Carboxymethyl)rifamycin

Nacimycin

Nancimycin

NCI-145-604

Rifomycin B

C01848

Rifamycin EP Impurity A

Rifaximin EP Impurity B (Rifamycin B)

Rifamycin B CRS

Rifamycin Impurity 1(Rifamycin EP Impurity A)（Rifamycin B)

4-O-(Carboxymethyl)-Rifamycin (Rifaximin Impurity)

Rifaximin EP Impurity B（Rifamycin EP Impurity A）

13929-35-6

C39H49NO14

Chiral Reagents

Intermediates & Fine Chemicals

Pharmaceuticals