ChemicalBook > CAS DataBase List > 4-O-(Carboxymethyl)rifamycin
4-O-(Carboxymethyl)rifamycin
- Product Name
- 4-O-(Carboxymethyl)rifamycin
- CAS No.
- 13929-35-6
- Chemical Name
- 4-O-(Carboxymethyl)rifamycin
- Synonyms
- C01848;Nacimycin;Nancimycin;Rifomycin B;NCI-145-604;Rifamycin B CRS;Rifamycin impurity A;Rifaximin EP Impurity B;Rifamycin EP Impurity A;Rifaximin impurity B (EP)
- CBNumber
- CB3913884
- Molecular Formula
- C39H49NO14
- Formula Weight
- 755.8
- MOL File
- 13929-35-6.mol
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4-O-(Carboxymethyl)rifamycin Property
- Melting point:
- 300° (dec 160-164°)
- alpha
- D20 -11° (methanol)
- Boiling point:
- 730.16°C (rough estimate)
- Density
- 1.2421 (rough estimate)
- refractive index
- 1.5350 (estimate)
- solubility
- DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated)
- pka
- 2.69±0.10(Predicted)
- BRN
- 604953
- Stability:
- Unstable in solution
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Safety
- Toxicity
- LD50 in mice (mg/kg): 2040 i.v., >3000 i.p., s.c., and orally (Sensi, 1964)
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- R0900000
- Product name
- Rifamycin B
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- r0900000
- Price
- $220
- Updated
- 2024/03/01
TRC
- Product number
- R508170
- Product name
- Rifamycin B
- Packaging
- 50mg
- Price
- $160
- Updated
- 2021/12/16
TRC
- Product number
- R508170
- Product name
- Rifamycin B
- Packaging
- 500mg
- Price
- $1295
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0009903
- Product name
- RIFAMYCIN B
- Purity
- 95.00%
- Packaging
- 500MG
- Price
- $1871.1
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0009903
- Product name
- RIFAMYCIN B
- Purity
- 95.00%
- Packaging
- 50MG
- Price
- $315
- Updated
- 2021/12/16
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4-O-(Carboxymethyl)rifamycin Chemical Properties,Usage,Production
Uses
Rifamycin B (Rifaximin EP Impurity B) is a Rifamycin (R508200) derivative as antibacterial agent.
Uses
A Rifamycin (R508200) derivative as antibacterial agent.
Definition
ChEBI: Rifamycin B is a carboxylic acid, an acetate ester, an organic heterotetracyclic compound and a member of rifamycins. It is a conjugate acid of a rifamycin B(2-).
Purification Methods
Rifamycin B forms yellow needles from *C6H6. Its solubilities are: H2O (0,027%), MeOH (2.62%) and EtOH (0.44%). It has UV max at 223, 304 and 245nm (A 1cm 555, 275 and 220). [Oppolzer & Prelog Helv Chim Acta 56 2287 1973, Oppolzer et al. Experientia 20 336 1964, X-ray: Brufani et al. Experientia 20 339 1964.]
4-O-(Carboxymethyl)rifamycin Preparation Products And Raw materials
Raw materials
Preparation Products
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