7-bromochroman-4-one
- Product Name
- 7-bromochroman-4-one
- CAS No.
- 18442-22-3
- Chemical Name
- 7-bromochroman-4-one
- Synonyms
- 7-bromo-2,3-dihydrochromen-4-one;7-Bromo Chromonone;7-Bromo-4-chromanone;7-bromochroman-4-one;7-BroMo-4-chroManone 97%;7-Bromo-4-Dihydrochromone;7-Bromochroman-4-one, 96%min;7-Bromochroman-4-one C9H7BrO2;7-bromo-2,3-dihydrobenzopyran-4-one;7-BROMOCHROMAN-4-ONE, CAS: 18442-22-3
- CBNumber
- CB3948156
- Molecular Formula
- C9H7BrO2
- Formula Weight
- 227.05
- MOL File
- 18442-22-3.mol
7-bromochroman-4-one Property
- Boiling point:
- 336.6±42.0 °C(Predicted)
- Density
- 1.621±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- Appearance
- White to yellow Solid
- InChI
- InChI=1S/C9H7BrO2/c10-6-1-2-7-8(11)3-4-12-9(7)5-6/h1-2,5H,3-4H2
- InChIKey
- DMEAYYYHWLCPCD-UHFFFAOYSA-N
- SMILES
- C1OC2=CC(Br)=CC=C2C(=O)C1
Safety
- HS Code
- 2932990090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B684988
- Product name
- 7-Bromochroman-4-one
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- W3989
- Product name
- 7-Bromochroman-4-one
- Packaging
- 250mg
- Price
- $76
- Updated
- 2021/12/16
- Product number
- FB140667
- Product name
- 7-Bromochroman-4-one
- Packaging
- 1g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 073339
- Product name
- 7-Bromochroman-4-one
- Purity
- 95+%
- Packaging
- 1g
- Price
- $44
- Updated
- 2021/12/16
- Product number
- 077088
- Product name
- 7-Bromochroman-4-one
- Purity
- 95+%
- Packaging
- 5g
- Price
- $148
- Updated
- 2021/12/16
7-bromochroman-4-one Chemical Properties,Usage,Production
Uses
Used as a intermediate for R & D.
Synthesis
7-Bromochroman-4-one was synthesized by hydrogenation addition of 7-Bromo-benzopyrone catalyzed by Wilkinson's catalyst Rhodium( Ⅰ) tris( triphenylphosphine) chloride[Rh( PPh3)3Cl]. The structure was confirmed by1 H NMR and MS. The optimum reaction conditions for synthesizing 7-Bromochroman-4-one were as follows: 5 0. 329 mol,ethanol as the solvent,c( 5) =0. 4 mol·L- 1,4% mol Rh( PPh3)3Cl as the catalyst,under 0. 3 MPa of hydrogen pressure,at 70℃ for 20 h,the yield was 79. 8%.
References
[1] Patent: WO2012/68234, 2012, A2. Location in patent: Page/Page column 629; 630
[2] Patent: WO2007/88450, 2007, A2. Location in patent: Page/Page column 22
[3] Journal of Medicinal Chemistry, 2016, vol. 59, # 22, p. 10228 - 10243
[4] Patent: US2014/200215, 2014, A1. Location in patent: Paragraph 1148; 1150
[5] Patent: US2009/202478, 2009, A1
7-bromochroman-4-one Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 7-bromochroman-4-one manufacturers
- Product
- 7-Bromo-4-chromanone 18442-22-3
- Price
- US $124.00-370.00/g
- Min. Order
- 5g
- Purity
- 0.98
- Supply Ability
- 25kg
- Release date
- 2023-12-07
- Product
- 7-Bromo-4-chromanone 18442-22-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 98%minHPLC
- Supply Ability
- 200kgs/month
- Release date
- 2021-11-04
- Product
- 7-Bromo-4-chromanone 18442-22-3
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2020-01-14