6-Bromo-2,3-dihydro-4H-chromen-4-one
Uses- Product Name
- 6-Bromo-2,3-dihydro-4H-chromen-4-one
- CAS No.
- 49660-57-3
- Chemical Name
- 6-Bromo-2,3-dihydro-4H-chromen-4-one
- Synonyms
- EOS-60332;6-BROMOCHROMANONE;AKOS BBS-00006811;BUTTPARK 35\07-34;6-Bromo-4-chromone;6-Bromo-4-chromanone;6-BROMOCHROMAN-4-ONE;6-BroMo-4-chroManone 97%;6-Bromochroman-4-one 98%;6-Bromo-4-chromanone≥ 98% (GC)
- CBNumber
- CB2318893
- Molecular Formula
- C9H7BrO2
- Formula Weight
- 227.05
- MOL File
- 49660-57-3.mol
6-Bromo-2,3-dihydro-4H-chromen-4-one Property
- Melting point:
- 77-83°C
- Boiling point:
- 336.6±42.0 °C(Predicted)
- Density
- 1.621±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- color
- White to Orange to Green
- InChI
- InChI=1S/C9H7BrO2/c10-6-1-2-9-7(5-6)8(11)3-4-12-9/h1-2,5H,3-4H2
- InChIKey
- PFLPVOXSUCCZDH-UHFFFAOYSA-N
- SMILES
- C1OC2=CC=C(Br)C=C2C(=O)C1
- CAS DataBase Reference
- 49660-57-3(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 732788
- Product name
- 6-Bromo-4-chromanone
- Packaging
- 250mg
- Price
- $130
- Updated
- 2023/01/07
- Product number
- B5843
- Product name
- 6-Bromo-4-chromanone
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $18
- Updated
- 2025/07/31
- Product number
- B5843
- Product name
- 6-Bromo-4-chromanone
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $69
- Updated
- 2025/07/31
- Product number
- B691348
- Product name
- 6-Bromo-2,3-dihydro-4h-chromen-4-one
- Packaging
- 10g
- Price
- $155
- Updated
- 2021/12/16
- Product number
- B691348
- Product name
- 6-Bromo-2,3-dihydro-4h-chromen-4-one
- Packaging
- 25g
- Price
- $360
- Updated
- 2021/12/16
6-Bromo-2,3-dihydro-4H-chromen-4-one Chemical Properties,Usage,Production
Uses
4-Dihydrochromone is a class of natural compounds with excellent biological activities, including anticancer, antibacterial, anti-inflammatory, and anti-allergic activities, as well as antiplatelet aggregation activities. 6-Bromo-4-dihydrochromone is a derivative of 4-dihydrochromone and can be used as a pharmaceutical intermediate.
Chemical Properties
Pale yellow crystalline solid
Synthesis
93670-18-9
49660-57-3
3-(4-Bromophenoxy)propionic acid (150 g, 0.61 mol) was slowly added to 1.0 liter of concentrated sulfuric acid at room temperature with continuous stirring for 1 hour. Upon completion of the reaction, the mixture was carefully poured into 500 g of ice water, whereupon a white solid precipitated. The white solid was separated by filtration and dried naturally in air. The crude product was purified by recrystallization using ethanol, resulting in 89 g (64% yield) of the target compound 6-bromobenzodihydropyran-4-one as a white solid.
References
[1] E-Journal of Chemistry, 2012, vol. 9, # 3, p. 1251 - 1256
[2] Patent: CN106699716, 2017, A. Location in patent: Paragraph 0022; 0035
[3] Australian Journal of Chemistry, 2010, vol. 63, # 11, p. 1582 - 1593
[4] Journal of the American Chemical Society, 1951, vol. 73, p. 4205,4207
[5] Tetrahedron, 2017, vol. 73, # 27-28, p. 3913 - 3922
6-Bromo-2,3-dihydro-4H-chromen-4-one Preparation Products And Raw materials
Raw materials
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View Lastest Price from 6-Bromo-2,3-dihydro-4H-chromen-4-one manufacturers
- Product
- 6-Bromo-2,3-dihydro-4H-chromen-4-one 49660-57-3
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-17
- Product
- 6-Bromo-2,3-dihydro-4H-chromen-4-one 49660-57-3
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-26
- Product
- 6-Bromo-2,3-dihydro-4H-chromen-4-one 49660-57-3
- Price
- US $20.00-367.00/g
- Min. Order
- 25g
- Purity
- 0.99
- Supply Ability
- 25kg
- Release date
- 2023-12-25