ChemicalBook > CAS DataBase List > 6-Bromo-2,3-dihydro-4H-chromen-4-one

6-Bromo-2,3-dihydro-4H-chromen-4-one

Uses

Product Name: 6-Bromo-2,3-dihydro-4H-chromen-4-one
CAS No.: 49660-57-3
Chemical Name: 6-Bromo-2,3-dihydro-4H-chromen-4-one
Synonyms: EOS-60332;6-BROMOCHROMANONE;AKOS BBS-00006811;BUTTPARK 35\07-34;6-Bromo-4-chromone;6-Bromo-4-chromanone;6-BROMOCHROMAN-4-ONE;6-BroMo-4-chroManone 97%;6-Bromochroman-4-one 98%;6-Bromo-4-chromanone≥ 98% (GC)
CBNumber: CB2318893
Molecular Formula: C9H7BrO2
Formula Weight: 227.05
MOL File: 49660-57-3.mol

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6-Bromo-2,3-dihydro-4H-chromen-4-one Property

Melting point:: 77-83°C
Boiling point:: 336.6±42.0 °C(Predicted)
Density: 1.621±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: powder to crystal
color: White to Orange to Green
InChI: InChI=1S/C9H7BrO2/c10-6-1-2-9-7(5-6)8(11)3-4-12-9/h1-2,5H,3-4H2
InChIKey: PFLPVOXSUCCZDH-UHFFFAOYSA-N
SMILES: C1OC2=CC=C(Br)C=C2C(=O)C1
CAS DataBase Reference: 49660-57-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
HS Code: 2914390090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 732788
Product name: 6-Bromo-4-chromanone
Packaging: 250mg
Price: $130
Updated: 2023/01/07

TCI Chemical

Product number: B5843
Product name: 6-Bromo-4-chromanone
Purity: >98.0%(GC)
Packaging: 1g
Price: $18
Updated: 2025/07/31

TCI Chemical

Product number: B5843
Product name: 6-Bromo-4-chromanone
Purity: >98.0%(GC)
Packaging: 5g
Price: $69
Updated: 2025/07/31

TRC

Product number: B691348
Product name: 6-Bromo-2,3-dihydro-4h-chromen-4-one
Packaging: 10g
Price: $155
Updated: 2021/12/16

TRC

Product number: B691348
Product name: 6-Bromo-2,3-dihydro-4h-chromen-4-one
Packaging: 25g
Price: $360
Updated: 2021/12/16

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6-Bromo-2,3-dihydro-4H-chromen-4-one Chemical Properties,Usage,Production

Uses

4-Dihydrochromone is a class of natural compounds with excellent biological activities, including anticancer, antibacterial, anti-inflammatory, and anti-allergic activities, as well as antiplatelet aggregation activities. 6-Bromo-4-dihydrochromone is a derivative of 4-dihydrochromone and can be used as a pharmaceutical intermediate.

Chemical Properties

Pale yellow crystalline solid

Synthesis

93670-18-9

49660-57-3

3-(4-Bromophenoxy)propionic acid (150 g, 0.61 mol) was slowly added to 1.0 liter of concentrated sulfuric acid at room temperature with continuous stirring for 1 hour. Upon completion of the reaction, the mixture was carefully poured into 500 g of ice water, whereupon a white solid precipitated. The white solid was separated by filtration and dried naturally in air. The crude product was purified by recrystallization using ethanol, resulting in 89 g (64% yield) of the target compound 6-bromobenzodihydropyran-4-one as a white solid.

References

[1] E-Journal of Chemistry, 2012, vol. 9, # 3, p. 1251 - 1256
[2] Patent: CN106699716, 2017, A. Location in patent: Paragraph 0022; 0035
[3] Australian Journal of Chemistry, 2010, vol. 63, # 11, p. 1582 - 1593
[4] Journal of the American Chemical Society, 1951, vol. 73, p. 4205,4207
[5] Tetrahedron, 2017, vol. 73, # 27-28, p. 3913 - 3922

6-Bromo-2,3-dihydro-4H-chromen-4-one Preparation Products And Raw materials

Raw materials

2-Oxetanone Polyphosphoric acid Diethyl ether 4-Bromophenol

Preparation Products

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6-Bromo-2,3-dihydro-4H-chromen-4-one Suppliers

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View Lastest Price from 6-Bromo-2,3-dihydro-4H-chromen-4-one manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 6-Bromo-2,3-dihydro-4H-chromen-4-one 49660-57-3
Price: US $2.20-8.80/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-17

Hebei Chuanghai Biotechnology Co., Ltd

Product: 6-Bromo-2,3-dihydro-4H-chromen-4-one 49660-57-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-26

Shanghai UCHEM Inc.

Product: 6-Bromo-2,3-dihydro-4H-chromen-4-one 49660-57-3
Price: US $20.00-367.00/g
Min. Order: 25g
Purity: 0.99
Supply Ability: 25kg
Release date: 2023-12-25

49660-57-3, 6-Bromo-2,3-dihydro-4H-chromen-4-oneRelated Search:

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BUTTPARK 35\07-34

6-Bromochromanone (6-Bromochroman-4-one)

6-Bromo-2,3-dihydro-4H-chromen-4-one 6-Bromo-4-chromanone

6-broMo-3,4-dihydro-2H-1-benzopyran-2-one

6-BroMo-4-chroManone 97%

4H-1-BENZOPYRAN-4-ONE, 6-BROMO-2,3-DIHYDRO-

6-BROMOCHROMANONE

6-BROMOCHROMAN-4-ONE

6-BROMO-2,3-DIHYDRO-4H-CHROMEN-4-ONE

AKOS BBS-00006811

6-Bromo-4-chromanone

6-Bromo-4-chromanone≥ 98% (GC)

6-BroMo-2,3-dihydro-4H-1-benzopyran-4-one

EOS-60332

6-Bromochroman-4-one 98%

6-Bromo-2,3-Dihydro-4H-Chromen-4-One,>98%

6-Bromo-4-chromone

6-Bromo-2,3-dihydro-4H-chromen-4-one ISO 9001：2015 REACH

ethyl4-(4-methoxy-3-methylphenyl)-2,7-dioxobutanoate

6-Bromo-2,3-dihydro-4H-chromen-4-one 98%

49660-57-3