5-BROMO-1,2-DIMETHYL-1H-IMIDAZOLE
- Product Name
- 5-BROMO-1,2-DIMETHYL-1H-IMIDAZOLE
- CAS No.
- 24134-09-6
- Chemical Name
- 5-BROMO-1,2-DIMETHYL-1H-IMIDAZOLE
- Synonyms
- 5-broMo-1,2-diMethyliMidazole;4-BROMO-1,5-DIMETHYLIMIDAZOLE;5-BROMO-1,2-DIMETHYL-1H-IMIDAZOLE;1,2-Dimethyl-5-bromo-1H-imidazole;1H-IMidazole,5-broMo-1,2-diMethyl-;5-Bromo-1,2-dimethyl-1H-imidazole 96%;5-Bromo-1,2-dimethyl-1H-imidazole ,97%
- CBNumber
- CB4104489
- Molecular Formula
- C5H7BrN2
- Formula Weight
- 175.03
- MOL File
- 24134-09-6.mol
5-BROMO-1,2-DIMETHYL-1H-IMIDAZOLE Property
- Melting point:
- 91 °C
- Boiling point:
- 266.6±13.0 °C(Predicted)
- Density
- 1.58±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- form
- solid
- pka
- 5.93±0.25(Predicted)
- color
- beige
- InChI
- InChI=1S/C5H7BrN2/c1-4-7-3-5(6)8(4)2/h3H,1-2H3
- InChIKey
- WIRCWIXZNDCIST-UHFFFAOYSA-N
- SMILES
- C1(C)N(C)C(Br)=CN=1
- CAS DataBase Reference
- 24134-09-6
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H226Flammable liquid and vapour
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- B691623
- Product name
- 5-Bromo-1,2-dimethyl-1H-imidazole
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B691623
- Product name
- 5-Bromo-1,2-dimethyl-1H-imidazole
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- CS-0036019
- Product name
- 5-Bromo-1,2-dimethyl-1H-imidazole
- Purity
- 99.55%
- Packaging
- 1g
- Price
- $54
- Updated
- 2021/12/16
- Product number
- 3H32-9-97
- Product name
- 5-Bromo-1,2-dimethyl-1H-imidazole
- Purity
- 96%
- Packaging
- 1g
- Price
- $122
- Updated
- 2021/12/16
- Product number
- CS-0036019
- Product name
- 5-Bromo-1,2-dimethyl-1H-imidazole
- Purity
- 99.55%
- Packaging
- 5g
- Price
- $161
- Updated
- 2021/12/16
5-BROMO-1,2-DIMETHYL-1H-IMIDAZOLE Chemical Properties,Usage,Production
Synthesis
1739-84-0
24134-09-6
General procedure for the synthesis of 5-bromo-1,2-dimethylimidazole from 1,2-dimethylimidazole: N-bromosuccinimide (NBS) (169 mg, 0.95 mmol) was added to a solution of dimethylformamide (DMF) (5 mL) of 1,2-dimethyl-1H-imidazole (1a) (96 mg, 1 mmol) at room temperature, and the reaction mixture was to be stirred for 3 hours away from light. After completion of the reaction, the resulting orange-yellow solution was diluted with ethyl acetate (EtOAc) (50 mL) and washed sequentially with 10% aqueous sodium hydroxide (2 x 50 mL), water (50 mL) and saturated saline (50 mL). The aqueous phase was then back-extracted with ethyl acetate (50 mL), and all organic phases were combined, dried with anhydrous sodium sulfate (Na2SO4) and filtered. The filtrate was concentrated under reduced pressure to give 5-bromo-1,2-dimethylimidazole as colorless crystals (3.78 g, 76% yield).
References
[1] Advanced Synthesis and Catalysis, 2016, vol. 358, # 4, p. 597 - 609
[2] Tetrahedron, 2004, vol. 60, # 37, p. 8065 - 8071
[3] Patent: US2014/107097, 2014, A1. Location in patent: Paragraph 0332
[4] Tetrahedron Letters, 2015, vol. 56, # 25, p. 3855 - 3857
5-BROMO-1,2-DIMETHYL-1H-IMIDAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
5-BROMO-1,2-DIMETHYL-1H-IMIDAZOLE Suppliers
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