ChemicalBook > CAS DataBase List > 1,2-Dimethylimidazole

1,2-Dimethylimidazole

Product Name
1,2-Dimethylimidazole
CAS No.
1739-84-0
Chemical Name
1,2-Dimethylimidazole
Synonyms
DiMethyliMidazole;1,2-dimethyl-1h-imidazole;1,2-dimethyl-1h-imidazol;1,2-Dimethylimidazol;39-41℃;1,2-DimethyL;Lupragen DMI;LUPRAGEN(R) DMI;AKOS BBS-00004287;dimethylglyoxaline
CBNumber
CB6196161
Molecular Formula
C5H8N2
Formula Weight
96.13
MOL File
1739-84-0.mol
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1,2-Dimethylimidazole Property

Melting point:
37-39 °C (lit.)
Boiling point:
204 °C (lit.)
Density 
1.084 g/mL at 25 °C (lit.)
vapor pressure 
1 mm Hg ( 20 °C)
refractive index 
1.5000 (estimate)
Flash point:
198 °F
storage temp. 
Store below +30°C.
pka
7.76±0.25(Predicted)
form 
Low Melting Mass
Specific Gravity
1.084
color 
Colorless to yellow
PH
12.6 (500g/l, H2O, 20℃)
Odor
Amine-like odor
Water Solubility 
Soluble in water.
BRN 
108457
InChIKey
GIWQSPITLQVMSG-UHFFFAOYSA-N
LogP
0.11 at 25℃
CAS DataBase Reference
1739-84-0(CAS DataBase Reference)
NIST Chemistry Reference
1H-Imidazole, 1,2-dimethyl-(1739-84-0)
EPA Substance Registry System
1H-Imidazole, 1,2-dimethyl- (1739-84-0)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-38-41
Safety Statements 
24-26-2
RIDADR 
UN 3263 8/PG 2
WGK Germany 
2
RTECS 
NI4838854
Autoignition Temperature
896 °F
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29332990
Toxicity
LD50 orally in Rabbit: 1300 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
136131
Product name
1,2-Dimethylimidazole
Purity
98%
Packaging
5g
Price
$29.09
Updated
2025/07/31
Sigma-Aldrich
Product number
136131
Product name
1,2-Dimethylimidazole
Purity
98%
Packaging
100g
Price
$48.4
Updated
2025/07/31
Sigma-Aldrich
Product number
8.03245
Product name
1,2-Dimethylimidazole
Purity
for synthesis
Packaging
100mL
Price
$55.6
Updated
2025/07/31
Sigma-Aldrich
Product number
8.03245
Product name
1,2-Dimethylimidazole
Purity
for synthesis
Packaging
500mL
Price
$215
Updated
2023/01/07
TCI Chemical
Product number
D1562
Product name
1,2-Dimethylimidazole
Purity
>98.0%(GC)
Packaging
25g
Price
$42
Updated
2025/07/31
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1,2-Dimethylimidazole Chemical Properties,Usage,Production

Chemical Properties

colorless to yellow low melting mass

Uses

1,2-Dimethylimidazole is used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It also can be used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.

Uses

1,2-Dimethylimidazole was used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It was also used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.

Definition

ChEBI: 1,2-dimethylimidazole is a member of imidazoles.

General Description

1,2-Dimethylimidazole reacts with copper(II) tetraacetate to yield cis-bis(acetato)bis(1,2-dimethylimidazole) copper(II) complex. It undergoes Menschutkin reaction with benzyl bromide to yield 3-benzyl-1,2-dimethylimidazolium bromide and kinetics of reaction was studied in various ionic liquids and molecular organic solvents.

Flammability and Explosibility

Not classified

Synthesis

131543-46-9

75-07-0

74-89-5

616-47-7

1739-84-0

693-98-1

A high-pressure microreactor equipped with three micro-mixers was used for the synthesis. It was operated as follows: an aqueous methylamine solution (0.33 mol/L) was fed from tank 1 via pump 1 at a flow rate of 0.68 mL/min; an aqueous acetaldehyde solution (0.33 mol/L) was fed from tank 3 via pump 3A at a flow rate of 63 mL/min while nearby water (0.33 mol/L) flowed at a flow rate of 1.13 mL/min; an aqueous glyoxal solution ( 0.33 mol/L) was fed from tank 4 via pump 4 at a flow rate of 0.56 mL/min. The reaction pressure was set to 30 MPa and the final flow rate was 8.0 mL/min. The temperature of the first micro-mixer and the 2.4 m reaction tube was controlled at 25 °C by the thermostat chamber 1 , under which the mixing and reaction of methylamine with acetaldehyde was carried out. Subsequently, in the second micro-mixer, the reaction mixture was mixed with ammonia and kept at 25 °C in the constant temperature chamber 2, and the reaction was fully mixed and reacted in the 0.1 m reaction tube. Next, glyoxal was added to the reaction system and fully reacted in a 0 m reaction tube. Subsequently, the temperature of the reaction zone was raised to 70 °C and the reaction was continued in a 25 μm reaction tube. Finally, the reaction mixture was cooled to 5 °C by a heat exchanger, depressurized to atmospheric pressure by a pressure reducing valve, and the aqueous solution obtained under cooling in ice water (0 °C to 4 °C) was collected. The residence time of the reaction part was 37 seconds throughout the reaction. For analysis, the product was diluted 10-fold with ice water, if necessary, and analyzed immediately using a gas chromatograph. The reaction tube was made of stainless steel (SUS316) with an inner diameter of 0.5 mm. the yield of the product 1,2-dimethylimidazole was 85.1%. The quantitative analysis was performed on an Agilent gas chromatograph (GC 6890, hydrogen flame ionization detector) with an HP-INNOWAX column (inner diameter 0.32 mm, film thickness 0.25 μm, length 30 m) manufactured by J & W Co. The yield of each product (1,2-dimethylimidazole, 1-methylimidazole, 2-methylimidazole, and imidazole) was determined by preparing standard curves for each product. The yield of each product was calculated based on the concentration obtained by conversion of the standard curve as follows: 1,2-dimethylimidazole 85.1%, 1-methylimidazole 6.27%, 2-methylimidazole 6.59%, and imidazole 2.06%.

Purification Methods

Crystallise the imidazole from *benzene, dry and store it at 0-4o. The picrate crystallises from H2O or EtOH with m 181o. [Balaban & Pymann J Chem Soc 125 1570 1924, Gorun et al. J Am Chem Soc 109 4244 1987, Beilstein 23 H 66, 23 II 56, 23 III/IV 594.]

References

[1] Patent: JP2016/222615, 2016, A. Location in patent: Paragraph 0051-0052

1,2-Dimethylimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

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1,2-Dimethylimidazole Suppliers

Jiangxi JinKai Chemical Co.,Ltd
Tel
15376072011
Email
sales3@dyckbiotech.com
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China
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58
Jinan Xinda Chemical Co. LTD
Tel
0531-84212239; 18615526239
Email
363436853@qq.com
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China
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190
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58
Shandong longyue of chemical co., LTD
Tel
15318857512
Email
1912317598@qq.com
Country
China
ProdList
44
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58
Linyi Hongda Chemical Co., Ltd
Tel
0539-7578168 13791585810
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46439760@qq.com
Country
China
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Shandong Xinyang Chemical Co., Ltd
Tel
13287720377
Email
3585673409@qq.com
Country
China
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176
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58
JYS
Tel
13545274181
Email
3870253201@qq.com
Country
China
ProdList
2114
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
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65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
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84
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View Lastest Price from 1,2-Dimethylimidazole manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
1,2-Dimethylimidazole 1739-84-0
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2024-11-29
HebeiShuoshengImportandExportco.,Ltd
Product
1,2-Dimethylimidazole 1739-84-0
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-08
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
1,2-Dimethylimidazole 1739-84-0
Price
US $78.00-35.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-20

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