Ociperlimab

Product Name: Ociperlimab
CAS No.: 2342597-93-5
Chemical Name: Ociperlimab
Synonyms: Ociperlimab;Ociperlimab (anti-TIGIT);Research Grade Ociperlimab;Research Grade Ociperlimab (DHH72405)
CBNumber: CB410617025
Formula Weight: 0
MOL File: Mol file

More

Less

Ociperlimab Property

form: Liquid
color: Colorless to light yellow

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

Ociperlimab Chemical Properties,Usage,Production

Uses

Ociperlimab is a humanized IgG1 anti-TIGIT antibody. Ociperlimab binds to the extracellular domain of human TIGIT with high affinity (KD = 0.135 nM). Ociperlimab blocks the interaction between TIGIT and its ligands PVR or PVR-L2. Ociperlimab can be used in research of cancer[1][2].

in vivo

Ociperlimab (BGB-A1217; 3 and 10 mg/kg; i.p.; CT26 WT tumor-bearing humanized TIGIT knock-in mice and MC38 tumor-bearing humanized TIGIT knock-in mice) elicits anti-tumor efficacy in an Fc-dependent manner^[1].

Animal Model:	CT26 WT tumor-bearing humanized TIGIT knock-in mice and MC38 tumor-bearing humanized TIGIT knock-in mice^[1]
Dosage:	3 and 10 mg/kg
Administration:	Intraperitoneal injection
Result:	Inhibited tumor growth compared to the single agent treatment groups.

References

[1] Chen X, et, al. An Fc-Competent Anti-Human TIGIT Blocking Antibody Ociperlimab (BGB-A1217) Elicits Strong Immune Responses and Potent Anti-Tumor Efficacy in Pre-Clinical Models. Front Immunol. 2022 Feb 22;13:828319. DOI:10.3389/fimmu.2022.828319
[2] Zhu J, et, al. Immune Checkpoints and targeted agents in relapse and graft-versus-host disease after hematopoietic stem cell transplantation. Mol Biol Rep. 2022 Dec 26. DOI:10.1007/s11033-022-08220-4

Ociperlimab Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Ociperlimab Suppliers

China 15 Global 15

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Guangzhou Hongyuan Chemical Co.,Ltd

Tel: 15817493340
Email: 981810490@qq.com
Country: China
ProdList: 1566
Advantage: 58

Wuhan Chemstan Biotechnology Co., Ltd.

Tel: 027-65317797 15926423062
Fax: QQ：422450190
Email: 422450190@qq.com
Country: China
ProdList: 10308
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Biolab Reagents

Tel: 027-65279366 18108604356
Email: products@biolabreagent.com
Country: China
ProdList: 9868
Advantage: 58

Wanxin Biotechnology (Jiaxing) Co., LTD

Tel: 0573-83568680 18057391398
Email: 3956524501@qq.com
Country: China
ProdList: 1442
Advantage: 58

Atagenix Laboratories

Tel: 027-87008169 17762441161
Email: info@atagenix.com
Country: China
ProdList: 10001
Advantage: 58

AntibodySystem Laboratories SAS

Tel: 33175446423
Email: support@antibodysystem.com
Country: China
ProdList: 6739
Advantage: 58

Selleck Chemicals

Tel: 400-668-6834
Email: info@selleck.cn
Country: China
ProdList: 6071
Advantage: 58

Cell Sciences

Tel: 9785721070
Email: info@cellsciences.com
Country: China
ProdList: 6308
Advantage: 58

Hangzhou MolCore BioPharmatech Co.,Ltd.

Tel: +86-057181025280; +8617767106207
Fax: 0571-85806285
Email: sales@molcore.com
Country: China
ProdList: 49734
Advantage: 58

Guangzhou Zhuanyan Biotechnology Co., Ltd.

Tel: 18926165828
Country: CHINA
ProdList: 198
Advantage: 58

Hangzhou Xiangyan Technology Co., Ltd.

Tel: 13185052974
Country: CHINA
ProdList: 149
Advantage: 58

Shenzhen Campbell Biotechnology Co., Ltd.

Tel: 18028747627
Country: CHINA
ProdList: 191
Advantage: 58

2342597-93-5, OciperlimabRelated Search:

Recaticimab Emerfetamab Anatumomab Research Grade Clivatuzumab (DHD14205) Petosemtamab Lorigerlimab Spartalizumab Tuvonralimab Timolumab Dusigitumab

Ociperlimab

Research Grade Ociperlimab (DHH72405)

Research Grade Ociperlimab

Ociperlimab (anti-TIGIT)

2342597-93-5