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Ranitidinebismuthcitrate

Product Name
Ranitidinebismuthcitrate
CAS No.
128345-62-0
Chemical Name
Ranitidinebismuthcitrate
Synonyms
Pylorid;Gastrimuto;Ranitidine bismutrex;RANTIDINEBISMUTHCITRATE;TIANFU CHEM-- Ranitidinebismuthcitrate;2-Hydroxy-1,2,3-propanetricarboxylic acid bismuth(3+) salt compd with N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine
CBNumber
CB41073641
Molecular Formula
C19H30N4O10S
Formula Weight
506.53
MOL File
128345-62-0.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0009220
Product name
RANITIDINE BISMUTH CITRATE
Purity
95.00%
Packaging
5MG
Price
$505.82
Updated
2021/12/16
AvaChem
Product number
2622
Product name
Ranitidine bismuth citrate
Packaging
100mg
Price
$290
Updated
2021/12/16
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Ranitidinebismuthcitrate Chemical Properties,Usage,Production

Description

Ranitidine bismuth citrate, a novel salt formed from ranitidine and a bismuth citrate complex, is a new agent introduced in the United Kingdom for the treatment of duodenal and benign gastric ulcers, for eradication of Helicobacfer pylori, and for prevention of relapse of duodenal ulcer when administered in combination with an antibiotic such as clarithromycin or amoxicillin. Ranitidine is a potent histamine H2-receptor antagonist with ability to inhibit gastric acid secretion. Other type of agents such as tripotassium dicitrato bismuthate exert their therapeutic effects in peptic ulceration by providing a protective coating to the ulcer crater, stimulating endogenous prostaglandin production, and inhibiting pepsin activity. More significantly, they inhibit micro-organism Helicobacfer pylori, a prevalent, specifically human pathogen associated with gastritis and gastric ulcers. The title compound possesses a novel combination of properties of the above two types of drugs and displays excellent therapeutic efficacy in clinical studies. Ranitidine bismuth citrate is being investigated for use in gastritis and non-ulcerating dyspepsia, acute healing of gastrointestinal ulcer and in prevention of the recurrence of peptic ulcer disease.

Originator

Glaxo Wellcome (United Kingdom)

Uses

Antagonist (to histamine H2receptors).

brand name

Tritec (GlaxoSmithKline);Pylorid.

Hazard

A poison by ingestion.

Mechanism of action

Ranitidine bismuth citrate has been developed for combination therapy with antibiotics for eradication of H.p. Depending on the co-prescription, eradication ranged from 15 to 92 % in an intention-to-treat analysis . It is claimed to combine the antisecretory action of ranitidine with the antimicrobial and gastroprotective actions of bismuth.

Ranitidinebismuthcitrate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ranitidinebismuthcitrate manufacturers

Career Henan Chemical Co
Product
Ranitidinebismuthcitrate 128345-62-0
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200kgs
Release date
2020-01-28

128345-62-0, RanitidinebismuthcitrateRelated Search:


  • Pylorid
  • Ranitidine bismutrex
  • 2-Hydroxy-1,2,3-propanetricarboxylic acid bismuth(3+) salt compd with N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine
  • Gastrimuto
  • RANTIDINEBISMUTHCITRATE
  • TIANFU CHEM-- Ranitidinebismuthcitrate
  • 128345-62-0
  • C13H22N4O3SC6H5O7Bi