Physical Form
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Tandospirone citrate

Physical Form
Product Name
Tandospirone citrate
CAS No.
112457-95-1
Chemical Name
Tandospirone citrate
Synonyms
andospironecitrate;SM 3997;Methanospirone;SM-3997 citrate;tandospirone citrate;Tandopsirone citrate;Tandospirone-d8 Citrate;Tandospirone citrate (SM 3997);2-(Dicyclohexylphosphanyl)-1-(2-methoxy-6-(triethylsilyl)phenyl)-1H-pyrrole;(3aR,4R,7S,7aS)-2-(4-chlorobutyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
CBNumber
CB71270043
Molecular Formula
C21H29N5O2.C6H8O7
Formula Weight
575.615
MOL File
112457-95-1.mol
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Tandospirone citrate Property

Melting point:
169.5-170°
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
form 
Solid
color 
White to off-white
Water Solubility 
Water: 10.4 mg/mL (18.07 mM)
InChIKey
DMLGUJHNIWGCKM-DPFKZJTMNA-N
SMILES
[C@@]12(C(=O)N(CCCCN3CCN(C4=NC=CC=N4)CC3)C(=O)[C@]1([C@@]1(CC[C@]2(C1)[H])[H])[H])[H].C(O)(C(=O)O)(CC(=O)O)CC(=O)O |&1:0,22,23,26,r|
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-4598
Product name
Tandospirone(citrate)
Purity
98.87%
Packaging
5mg
Price
$96
Updated
2021/12/16
ChemScene
Product number
CS-4598
Product name
Tandospirone(citrate)
Purity
98.87%
Packaging
10mg
Price
$156
Updated
2021/12/16
ChemScene
Product number
CS-4598
Product name
Tandospirone(citrate)
Purity
98.87%
Packaging
25mg
Price
$336
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0015552
Product name
TANDOSPIRONE CITRATE
Purity
95.00%
Packaging
5MG
Price
$503.76
Updated
2021/12/16
Crysdot
Product number
CD31004535
Product name
Tandospironecitrate
Purity
98+%
Packaging
5mg
Price
$55
Updated
2021/12/16
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Tandospirone citrate Chemical Properties,Usage,Production

Physical Form

solid

Uses

Tandospirone citrate is a potent 5-HT1A partial agonist with a Ki value of 27 nM. Tandospirone citrate is approximately two to three orders of magnitude less potent at 5-HT2, 5-HT1C, alpha 1-adrenergic, alpha 2-adrenergic, and dopamine D1 and D2 receptors (Ki values ranging from 1300 to 41000 nM).
Anti-anxiety agent.

Definition

ChEBI: Tandospirone citrate is a citrate salt of tandospirone , comprising equimolar amounts of citric acid and tandospirone. It is an anxiolytic drug used in the treatment of anxiety disorders. It has a role as an anxiolytic drug and an antidepressant. It contains a tandospirone(1+).

Pharmacology

Tandospirone citrate is a partial agonist of the 5-hydroxytryptamine type 1A (5-HT1A) receptor,which selectively binds to the 5-HT1A receptor in the brain. The anti-anxiety effect is exerted by inhibiting the activities of the 5-HT1A system via selectively stimulating the 5-HT1A receptor widely distributed in these sites.

Side effects

The most common adverse reactions to Tandospirone citrate include drowsiness, dizziness, headache, nausea, malaise, rash, urticaria and pruritus. In addition, there are some symptoms that require special attention, such as those related to hepatic insufficiency and jaundice: general malaise, loss of appetite, yellowing of the skin and whites of the eyes. Excitement, sweating and trembling associated with serotonin syndrome. Fever, impaired consciousness, sweating associated with malignant syndrome. These symptoms are rarely considered initial symptoms of the indicated adverse reaction. However, if you experience discomfort, contact your doctor immediately.

Tandospirone citrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Tandospirone citrate Suppliers

Sichuan Credit Chemwerth Pharmaceutical Co., Ltd.
Tel
028-8512-3105 13111882551
Fax
+86 (28) 8512-3105
Country
China
ProdList
15
Advantage
50
Chengdu Aupone Pharmaceutical Co.,Ltd.
Tel
18980796919
Email
236656639@qq.com
Country
China
ProdList
30
Advantage
58
Chengdu D-innovation Pharmaceutical Co.,LTD
Tel
028-85929779 18009044761
Email
pengxing@d-innovation.com
Country
China
ProdList
296
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
Chemvon Biotechnology Co., Ltd
Tel
021-50790412
Fax
+86-21-50790419
Email
info@chemvon.com
Country
China
ProdList
371
Advantage
57
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
5050
Advantage
50
Chengdu D-innovation Pharmaceutical Co.,LTD
Tel
028-85929779 18009044761
Email
pengxing@d-innovation.com
Country
China
ProdList
59
Advantage
55
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
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View Lastest Price from Tandospirone citrate manufacturers

Wuhan Senwayer Century Chemical Co.,Ltd
Product
Tandospirone citrate 112457-95-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 TONS
Release date
2022-11-04
Zibo Hangyu Biotechnology Development Co., Ltd
Product
Tandospirone citrate 112457-95-1
Price
US $85.00-850.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-20
Biopole Pharmatech Co., Ltd.
Product
Tandospirone citrate 2563433
Price
US $0.00/g
Min. Order
1g
Purity
99.99%HPLC
Supply Ability
200kg
Release date
2024-02-04

112457-95-1, Tandospirone citrateRelated Search:


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