ChemicalBook > CAS DataBase List > Tandospirone citrate

Tandospirone citrate

Physical Form

Product Name: Tandospirone citrate
CAS No.: 112457-95-1
Chemical Name: Tandospirone citrate
Synonyms: andospironecitrate;SM 3997;Methanospirone;SM-3997 citrate;tandospirone citrate;Tandopsirone citrate;Tandospirone-d8 Citrate;Tandospirone citrate (SM 3997);2-(Dicyclohexylphosphanyl)-1-(2-methoxy-6-(triethylsilyl)phenyl)-1H-pyrrole;(3aR,4R,7S,7aS)-2-(4-chlorobutyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
CBNumber: CB71270043
Molecular Formula: C21H29N5O2.C6H8O7
Formula Weight: 575.615
MOL File: 112457-95-1.mol

Less

Tandospirone citrate Property

Melting point:: 169.5-170°
storage temp.: Inert atmosphere,Store in freezer, under -20°C
form: Solid
color: White to off-white
Water Solubility: Water: 10.4 mg/mL (18.07 mM)
InChIKey: DMLGUJHNIWGCKM-DPFKZJTMNA-N
SMILES: [C@@]12(C(=O)N(CCCCN3CCN(C4=NC=CC=N4)CC3)C(=O)[C@]1([C@@]1(CC[C@]2(C1)[H])[H])[H])[H].C(O)(C(=O)O)(CC(=O)O)CC(=O)O |&1:0,22,23,26,r|

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-4598
Product name: Tandospirone(citrate)
Purity: 98.87%
Packaging: 5mg
Price: $96
Updated: 2021/12/16

ChemScene

Product number: CS-4598
Product name: Tandospirone(citrate)
Purity: 98.87%
Packaging: 10mg
Price: $156
Updated: 2021/12/16

ChemScene

Product number: CS-4598
Product name: Tandospirone(citrate)
Purity: 98.87%
Packaging: 25mg
Price: $336
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0015552
Product name: TANDOSPIRONE CITRATE
Purity: 95.00%
Packaging: 5MG
Price: $503.76
Updated: 2021/12/16

Crysdot

Product number: CD31004535
Product name: Tandospironecitrate
Purity: 98+%
Packaging: 25mg
Price: $194
Updated: 2021/12/16

Less

Tandospirone citrate Chemical Properties,Usage,Production

Physical Form

solid

Uses

Tandospirone citrate is a potent 5-HT1A partial agonist with a Ki value of 27 nM. Tandospirone citrate is approximately two to three orders of magnitude less potent at 5-HT2, 5-HT1C, alpha 1-adrenergic, alpha 2-adrenergic, and dopamine D1 and D2 receptors (Ki values ranging from 1300 to 41000 nM).
Anti-anxiety agent.

Definition

ChEBI: Tandospirone citrate is a citrate salt of tandospirone , comprising equimolar amounts of citric acid and tandospirone. It is an anxiolytic drug used in the treatment of anxiety disorders. It has a role as an anxiolytic drug and an antidepressant. It contains a tandospirone(1+).

Pharmacology

Tandospirone citrate is a partial agonist of the 5-hydroxytryptamine type 1A (5-HT1A) receptor,which selectively binds to the 5-HT1A receptor in the brain. The anti-anxiety effect is exerted by inhibiting the activities of the 5-HT1A system via selectively stimulating the 5-HT1A receptor widely distributed in these sites.

Side effects

The most common adverse reactions to Tandospirone citrate include drowsiness, dizziness, headache, nausea, malaise, rash, urticaria and pruritus. In addition, there are some symptoms that require special attention, such as those related to hepatic insufficiency and jaundice: general malaise, loss of appetite, yellowing of the skin and whites of the eyes. Excitement, sweating and trembling associated with serotonin syndrome. Fever, impaired consciousness, sweating associated with malignant syndrome. These symptoms are rarely considered initial symptoms of the indicated adverse reaction. However, if you experience discomfort, contact your doctor immediately.

Tandospirone citrate Preparation Products And Raw materials

Raw materials

Preparation Products

Less

Tandospirone citrate Suppliers

China 134 India 2 United States 11 Global 147

Sichuan Credit Chemwerth Pharmaceutical Co., Ltd.

Tel: 028-8512-3105 13111882551
Fax: +86 (28) 8512-3105
Country: China
ProdList: 15
Advantage: 50

Chengdu Aupone Pharmaceutical Co.,Ltd.

Tel: 18980796919
Email: 236656639@qq.com
Country: China
ProdList: 30
Advantage: 58

Shanghai Jiapu Biotechnology Co., Ltd

Tel: 18221901645
Email: 18221901645@163.com
Country: China
ProdList: 68
Advantage: 58

Shandong Mingfeng Pharmaceutical and Technology Co. Ltd

Tel: -1345456643 15315114555
Fax: QQ:1345456643
Email: 1345456643@qq.com
Country: China
ProdList: 243
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Chemvon Biotechnology Co., Ltd

Tel: 021-50790412
Fax: +86-21-50790419
Email: info@chemvon.com
Country: China
ProdList: 371
Advantage: 57

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3506
Advantage: 58

Megchem Co., Ltd.

Tel: +86 (21) 5471-7132
Fax: +86 (21) 5471-6993
Country: China
ProdList: 344
Advantage: 58

Shandong Boluoda Biological Technology Co., Ltd.

Tel: 0531-68652053 15863796298;
Email: 2310993908@qq.com
Country: China
ProdList: 2437
Advantage: 58

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

Raw material medicin reagent co.,Ltd

Tel
Email: sales@njromanme.com
Country: China
ProdList: 4529
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai Resuperpharmtech Co., Ltd.

Tel: 02150565560; 17321237488
Email: kevin@resuperpharmtech.com
Country: China
ProdList: 356
Advantage: 58

Yantai ShengKailun Chemical Technology Co., Ltd.

Tel: 13356901049
Fax: QQ：1025383091
Email: 3119594100@qq.com
Country: China
ProdList: 7964
Advantage: 55

Shanghai Biopharmaleader Co., Ltd.

Tel: +86 18721201413
Fax: +86 (21) 5775-8967
Email: sales@biopharmaleader.com
Country: China
ProdList: 1720
Advantage: 58

Shanghai Zhen Li Biological Technology Co., Ltd

Tel: 021-16621358918; 18516310516
Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
ProdList: 19035
Advantage: 58

Hubei widely chemical technology Co., Ltd.

Tel: 027-83778895 18602735115
Fax: 027-51119224
Email: 18602735115@163.com
Country: China
ProdList: 2005
Advantage: 64

Bejing Famous Pharmaceutical Technology Co., Ltd.

Tel: 13331045123
Fax: 86-10-80339217
Email: 2559355526@qq.com
Country: China
ProdList: 14193
Advantage: 58

Chengdu Saint - Kay Biotechnology Co., Ltd.

Tel: 028-85157043 15882256948
Email: 676046971@qq.com
Country: China
ProdList: 4181
Advantage: 58

Chongqing Zhisheng Technology Co., Ltd.

Tel: 023-67586781 17783613370
Fax: QQ 2636861874
Email: 2636861874@qq.com
Country: China
ProdList: 446
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

Shanghai UCHEM Inc.

Tel: +862156762820 +86-13564624040
Email: sales@myuchem.com
Country: China
ProdList: 8460
Advantage: 58

Hefei Hirisun Pharmatech Co., Ltd

Tel: +8615056975894
Fax: 86-0551-62678551
Email: shawn@hirisunpharm.com
Country: CHINA
ProdList: 9911
Advantage: 58

Shanxi Xuanran Import and Export Trade Co., Ltd.

Tel: +8617735180244
Email: mike_yan@xuanranglobal.com
Country: CHINA
ProdList: 4017
Advantage: 58

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Tel: 86-571-88216897,88216896 13588875226
Fax: 86-571-88216895
Email: sales@hzclap.com
Country: CHINA
ProdList: 6312
Advantage: 58

Guangzhou Dreampharm Biotechnology Co., Ltd.

Tel: 020-36607679 19925672674
Fax: QQ 3008233717
Email: 3008233746@qq.com
Country: China
ProdList: 9883
Advantage: 12

Hubei Xingcheng Biotechnology Co., Ltd

Tel: 19171210221
Fax: QQ:3505191060
Email: 3371991952@qq.com
Country: China
ProdList: 994
Advantage: 58

Shanghai TenSus Biotechnology Co., Ltd.

Tel: 021-50895067 18616507272
Fax: 021-50895067
Email: tensus@163.com
Country: China
ProdList: 8073
Advantage: 58

Chengdu D-innovation Pharmaceutical Co.，LTD

Tel: 028-85929779 18881048017
Email: chenxuanruo@d-innovation.com
Country: China
ProdList: 262
Advantage: 58

Jinan blalong chemical co. LTD

Tel: 2710913286@.com
Email: 1513643261@qq.com
Country: China
ProdList: 14246
Advantage: 58

Shanghai Yanze Chemical Co., Ltd.

Tel: 021-021-13773155751 19975051755
Email: 260924549@qq.com
Country: China
ProdList: 10524
Advantage: 58

Chongqing Chemdad Co., Ltd

Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Country: China
ProdList: 39927
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Absin Bioscience Inc.

Tel: 021-38015121 18438616290
Email: lanwu@univ-bio.com
Country: China
ProdList: 24731
Advantage: 58

Fuxin Pharmaceutical

Tel: +86-021-021-50872116 +8613122107989
Email: contact@fuxinpharm.com
Country: China
ProdList: 10000
Advantage: 58

Shanghai Luofa Biochemical Technology Co., Ltd.

Tel: 021-51111890 15317326293
Email: sales@molnova.com
Country: China
ProdList: 4195
Advantage: 58

Chongqing Kangzhou Zhitong Pharmaceutical Technology Co., Ltd.

Tel: 173-08362167 17308362167
Email: 3090602484@qq.com
Country: China
ProdList: 568
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-025-85560043 17301488900
Fax: 025-85563444
Email: info@synzest.com
Country: China
ProdList: 9286
Advantage: 58

Shanghai Botuo Biotechnology Co., LTD

Tel: 16621358918
Fax: QQ:402135374
Email: botuopharma888@163.com
Country: China
ProdList: 9208
Advantage: 58

Aktin Chemicals, Inc.

Tel: 028-85159085
Email: info@aktinchem.com
Country: China
ProdList: 1860
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

Wuhan Yanzhe Technology Co., Ltd

Tel: 15527250409
Fax: QQ：2692360204
Email: wenhaotian12@163.com
Country: China
ProdList: 4171
Advantage: 58

Hubei Zhongshan Medical Technology Co., Ltd

Tel: 027-61907345 13397111514
Fax: 3443707954
Email: w13397111514@163.com
Country: China
ProdList: 1005
Advantage: 58

DONBOO AMINO ACID COMPANY

Tel: +8618051385538
Email: donboo@donboo.com
Country: China
ProdList: 9363
Advantage: 58

Guangzhou Juntang Technology Co., Ltd

Tel: 020-36607679 13502246435
Email: sales@dmstandards.com
Country: China
ProdList: 10945
Advantage: 58

Shandong Yuhe Pharmaceutical Technology Co., LTD

Tel: 15263077727
Fax: QQ：2938966534
Email: 1436425847@qq.com
Country: China
ProdList: 262
Advantage: 58

cjbscvictory

Tel: 13348960310
Email: 3003867561@qq.com
Country: China
ProdList: 10503
Advantage: 58

Less

View Lastest Price from Tandospirone citrate manufacturers

Wuhan JiyunZen Tech Co., Ltd.

Product: Tandospirone citrate 112457-95-1
Price: US $5.00-0.50/KG
Min. Order: 1KG
Purity: 99% hplc
Supply Ability: 500TONS
Release date: 2025-05-29

Dingwang Technology (Wuhan) Co., Ltd.

Product: Tandospirone citrate 112457-95-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 TONS
Release date: 2022-11-04

Zibo Hangyu Biotechnology Development Co., Ltd

Product: Tandospirone citrate 112457-95-1
Price: US $85.00-850.00/kg
Min. Order: 10kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-11-20

112457-95-1, Tandospirone citrateRelated Search:

(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid LCZ 696 Impurity C LCZ 696 Impurity B rac-Lipoic Acid Impurity 1 (S-Oxide) 3-(3-fluorobenzyl)-4-(3-fluoro-benzyloxy)benzaldehyde 4-Benzyl Albuterol [R(R*,R*]-2-amino-1-[p-(methylsulphonyl)phenyl]propane-1,3-diol PWKRNMKZGWGSDV-UHFFFAOYSA-N Tandospirone citrate Tandospirone 1,2-Cyclohexanedicarboximide Ammonium citrate tribasic cis-Octahydroisoindole 2-AZACYCLOOCTANONE cis-7-Azabicyclo[3.3.0]octane PIPERAZINE DL-MALATE N-Butyl-2-methyl-succinimide 4-AZA-TRICYCLO[5.2.1.0 2,6 ]DECANE

4,7-Methano-1H-isoindole-1,3(2H)-dione, hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-, (3aa,4b,7b,7aa)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)

4,7-Methano-1H-isoindole-1,3(2H)-dione, hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-, (3aR,4S,7R,7aS)-rel-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) (9CI)

SM 3997

tandospirone citrate

(3aα,4β,7β,7aα)-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione·citric acid

Methanospirone

Tandopsirone citrate

3aalpha,4alpha,5,6,7alpha,7aalpha-Hexahydro-2-[4- [4-(2-pyriMidinyl)-1-piperazinyl]butyl]-4,7-Methano-1H-isoindole-1,3(2H)-dione dihydrogen citrate

(3aR,4S,7R,7aS)-rel-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione 2-hydroxy-1,2,3-propanetricarboxylate (1:1)

SM-3997 citrate

rel-(3aR,4S,7R,7aS)-2-(4-(4-(Pyrimidin-2-yl)piperazin-1-yl)butyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione 2-hydroxypropane-1,2,3-tricarboxylate

andospironecitrate

Tandospirone citrate (SM 3997)

Tandospirone-d8 Citrate

SM3997,SM-3997,Tandospirone,Tandospirone citrate,Inhibitor,Serotonin Receptor,SM 3997,5-hydroxytryptamine Receptor,inhibit,5-HT Receptor

2-(Dicyclohexylphosphanyl)-1-(2-methoxy-6-(triethylsilyl)phenyl)-1H-pyrrole

4-((3aR,4S,7R,7aS)-1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl)butyl 4-(pyrimidin-2-yl)piperazine-1-carboxylate

(1S,2R,3S,4R)-3-((4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)carbamoyl)bicyclo[2.2.1]heptane-2-carboxylic acid

(3aR,3a'R,4S,4'S,7R,7aS,7'R,7a'S)-2,2'-(piperazine-1,4-diylbis(butane-4,1-diyl))bis(hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione)

(3aR,4R,7S,7aS)-2-(4-chlorobutyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione

(3aR,4S,7R,7aS)-2-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione 2-hydroxypropane-1,2,3-tricarboxylate

112457-95-1

C21H29N5O2C6H8O7

112457-95-1

API