Dimethyl2,2'-Dibromoadipate
- Product Name
- Dimethyl2,2'-Dibromoadipate
- CAS No.
- 868-72-4
- Chemical Name
- Dimethyl2,2'-Dibromoadipate
- Synonyms
- Nsc134297;Dimethyl 2,5-dibromoadipate;dimethyl2,2'-dibromoadipate;Dimethyl 2,5 Dibromoadepate;Dimethyl2,5-Dibromohexanedioate;Dimethyl 2,5-dibromoadipate, 96%;Hexanedioic acid, 2,5-dibromo-, 1,6-dimethyl ester
- CBNumber
- CB41073823
- Molecular Formula
- C8H12Br2O4
- Formula Weight
- 331.99
- MOL File
- 868-72-4.mol
Dimethyl2,2'-Dibromoadipate Property
- Melting point:
- 75-76 °C
- Boiling point:
- 182 °C(Press: 10 Torr)
- Density
- 1.6603 g/cm3
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C8H12Br2O4/c1-13-7(11)5(9)3-4-6(10)8(12)14-2/h5-6H,3-4H2,1-2H3
- InChIKey
- HVICCJCVLLCDFQ-UHFFFAOYSA-N
- SMILES
- C(OC)(=O)C(Br)CCC(Br)C(OC)=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- S915092
- Product name
- DIMETHYL 2,5-DIBROMOADIPATE
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $185
- Updated
- 2025/07/31
- Product number
- S915092
- Product name
- DIMETHYL 2,5-DIBROMOADIPATE
- Purity
- AldrichCPR
- Packaging
- 1g
- Price
- $179
- Updated
- 2024/03/01
- Product number
- D476808
- Product name
- Dimethyl2,5-Dibromohexanedioate
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- J96160
- Product name
- Dimethyl2,5-dibromohexanedioate
- Packaging
- 1g
- Price
- $38
- Updated
- 2021/12/16
- Product number
- CS-W005735
- Product name
- Dimethyl2,5-dibromohexanedioate
- Packaging
- 5g
- Price
- $38
- Updated
- 2021/12/16
Dimethyl2,2'-Dibromoadipate Chemical Properties,Usage,Production
Description
Dimethyl2,2'-Dibromoadipate is an important intermediate in organic synthesis, which can be produced from methanol and adipic acid.
Synthesis
67-56-1
124-04-9
868-72-4
The general procedure for the synthesis of dimethyl 2,5-dibromoadipate from methanol and adipic acid was as follows: Thionyl chloride (323 g, 2.71 mol) was slowly added dropwise in 70 ml portions to adipic acid (197 g, 1.35 mol) in a three-necked, round-bottomed flask fitted with a reflux condenser and a constant-pressure dropping funnel at 80 °C for 2 hours. The reaction mixture was stirred until the escape of gas ceased, at which point some of the solid adipic acid remained incompletely dissolved. Subsequently, the addition of another 100 ml of thionyl chloride was continued dropwise over a period of 7 hours and heating was continued until the gas escape stopped completely. The reaction mixture was cooled to ice bath temperature and bromine (473 g, 2.96 mol) was slowly added dropwise, during which the formation of a white precipitate was observed. The white precipitate was collected by filtration and purified by recrystallization with methanol to give 253 g of white powdery product in 53% yield. The product was characterized by 1H NMR (400 MHz, CDCl3, δppm): 2.00~2.05 (m, 2H), 2.28~2.35 (m, 2H), 3.80 (s, 6H), 4.24~4.26 (t, 2H).
References
[1] Chemistry - A European Journal, 2012, vol. 18, # 4, p. 1127 - 1141
[2] Journal of Organic Chemistry, 1972, vol. 37, p. 2418 - 2423
[3] Synthesis (Germany), 2012, vol. 44, # 11, p. 1736 - 1744
[4] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 21, p. 5855 - 5859
Dimethyl2,2'-Dibromoadipate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Dimethyl2,2'-Dibromoadipate manufacturers
- Product
- Dimethyl 2,5-dibromohexanedioate 868-72-4
- Price
- US $25.00/kg
- Min. Order
- 1kg
- Purity
- 99.96%
- Supply Ability
- 500ton
- Release date
- 2023-05-25
- Product
- Dimethyl 2,5-dibromohexanedioate 868-72-4
- Price
- US $30.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2023-10-09
- Product
- Dimethyl2,2'-Dibromoadipate 868-72-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2019-08-30