ChemicalBook > CAS DataBase List > 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro-1-methyl- (9CI)

7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro-1-methyl- (9CI)

Product Name
7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro-1-methyl- (9CI)
CAS No.
314021-93-7
Chemical Name
7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro-1-methyl- (9CI)
Synonyms
1-Methyl-1H-pyrazolo[4,3-d]pyriMidin-7-ol;1,6-dihydro-1-methyl-7H-Pyrazolo[4,3-d]pyrimidin-7-one;1-Methyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one;7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,6-dihydro-1-methyl-;7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro-1-methyl- (9CI)
CBNumber
CB41082384
Molecular Formula
C6H6N4O
Formula Weight
150.14
MOL File
314021-93-7.mol
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7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro-1-methyl- (9CI) Property

storage temp. 
2-8°C
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM1027255
Product name
1,6-DIHYDRO-1-METHYL-7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE
Purity
95.00%
Packaging
5MG
Price
$502.02
Updated
2021/12/16
AK Scientific
Product number
1082EM
Product name
1-Methyl-1H-pyrazolo[4,3-D]pyrimidin-7-OL
Packaging
100mg
Price
$796
Updated
2021/12/16
AK Scientific
Product number
1082EM
Product name
1-Methyl-1H-pyrazolo[4,3-D]pyrimidin-7-OL
Packaging
250mg
Price
$895
Updated
2021/12/16
AK Scientific
Product number
1082EM
Product name
1-Methyl-1H-pyrazolo[4,3-D]pyrimidin-7-OL
Packaging
5g
Price
$4224
Updated
2021/12/16
AccelPharmtech
Product number
P7122
Product name
1,6-dihydro-1-methyl-7H-Pyrazolo[4,3-d]pyrimidin-7-one
Purity
97.00%
Packaging
25G
Price
$6710
Updated
2021/12/16
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7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro-1-methyl- (9CI) Chemical Properties,Usage,Production

Synthesis

923283-54-9

3473-63-0

314021-93-7

GENERAL STEPS: To a mixture of 4-amino-1-methyl-1H-pyrazole-5-carboxylic acid methyl ester (0.92 g, 5.9 mmol) dissolved in 5 mL of a mixture of N,N-diisopropylethylamine (Hunig base) and 5 mL of n-butanol was added formamidine acetate (0.68 g, 6.5 mmol). The reaction mixture was heated to 110 °C and stirred for 1 hour. After completion of the reaction, it was cooled to room temperature, the white precipitate was collected by filtration and washed with ether. The resulting white solid was dried under reduced pressure to afford 1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7-ol (0.83 g, 94% yield). The product was characterized by 1H NMR (d6-DMSO): δ 4.33 (s, 3H), 8.50 (s, 1H), 8.80 (s, 1H); electrospray mass spectrometry (ES-MS) showed m/e = 151 ([M + H]+).

References

[1] Patent: US2007/27166, 2007, A1. Location in patent: Page/Page column 80

7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro-1-methyl- (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro-1-methyl- (9CI) manufacturers

Career Henan Chemical Co
Product
1-Methyl-1H-pyrazolo[4,3-d]pyrimidin-7-ol 314021-93-7
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
G/KG/TON
Release date
2020-01-31