1H-Benzimidazole-5-methanol,1-methyl-(9CI)
- Product Name
- 1H-Benzimidazole-5-methanol,1-methyl-(9CI)
- CAS No.
- 115576-91-5
- Chemical Name
- 1H-Benzimidazole-5-methanol,1-methyl-(9CI)
- Synonyms
- (1-Methyl-1H-benzo[d]imidazol-5-yl);(1-methyl-5-benzimidazolyl)methanol;1-METHYL-1H-BENZIMIDAZOLE-5-METHANOL;1H-Benzimidazole-5-methanol, 1-methyl-;(1-methyl-1H-benzimidazol-5-yl)methanol;1H-Benzimidazole-5-methanol,1-methyl-(9CI);(1-Methyl-1H-1,3-benzodiazol-5-yl)Methanol;(1-Methyl-1H-benzo[d]imidazol-5-yl)methanol
- CBNumber
- CB61301364
- Molecular Formula
- C9H10N2O
- Formula Weight
- 162.19
- MOL File
- 115576-91-5.mol
1H-Benzimidazole-5-methanol,1-methyl-(9CI) Property
- Melting point:
- 152.3 °C
- Boiling point:
- 357.4±34.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 14.13±0.10(Predicted)
- Appearance
- Brown to reddish brown Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- 2529AA
- Product name
- (1-Methyl-1H-benzo[d]imidazol-5-yl)methanol
- Packaging
- 250mg
- Price
- $178
- Updated
- 2021/12/16
- Product number
- 2529AA
- Product name
- (1-Methyl-1H-benzo[d]imidazol-5-yl)methanol
- Packaging
- 1g
- Price
- $355
- Updated
- 2021/12/16
- Product number
- CHM0077468
- Product name
- 1H-BENZIMIDAZOLE-5-METHANOL,1-METHYL-
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $909.56
- Updated
- 2021/12/16
- Product number
- 2529AA
- Product name
- (1-Methyl-1H-benzo[d]imidazol-5-yl)methanol
- Packaging
- 5g
- Price
- $945
- Updated
- 2021/12/16
- Product number
- 2529AA
- Product name
- (1-Methyl-1H-benzo[d]imidazol-5-yl)methanol
- Packaging
- 10g
- Price
- $1654
- Updated
- 2021/12/16
1H-Benzimidazole-5-methanol,1-methyl-(9CI) Chemical Properties,Usage,Production
Synthesis
53484-19-8
115576-91-5
General procedure for the synthesis of 1-methyl-1H-benzimidazole-5-methanol from ethyl 1-methyl-1H-benzimidazole-5-carboxylate: Step 1-1-5 (1-methyl-1H-benzimidazol-5-yl) methanol synthesis: lithium aluminum hydride (9.70 g, 256 mmol) was suspended in dry tetrahydrofuran (100 mL) under argon protection. A tetrahydrofuran solution (100 mL) of ethyl 1-methyl-1H-benzimidazole-5-carboxylate (26.1 g, 128 mmol) prepared in step 1-1-4 was added slowly and dropwise under cooling in an ice bath. The reaction mixture was stirred under ice bath cooling for 1 hour. Subsequently, the reaction was quenched by slow addition of saturated sodium bicarbonate solution under ice bath cooling. The solid precipitate was removed by filtration and the filtrate was concentrated. The concentrated residue was dissolved in chloroform, the organic phase was washed with saturated sodium bicarbonate solution and concentrated again. The concentrate was purified by silica gel column chromatography (eluent ratio: chloroform:methanol=10:1 to 5:1) to afford 1-methyl-1H-benzimidazole-5-methanol (11.4 g, 55% yield) as a light red powder. 1H-NMR (CDCl3) δ: 7.85 (s, 1H), 7.77 (s, 1H), 7.37-7.34 (m, 2H), 4.80 (s, 2H), 3.84 (s, 3H), 1.92 (brs, 1H). Mass spectrum, m/z: 162 (M+), 133 (base).
References
[1] Patent: US2013/79306, 2013, A1. Location in patent: Paragraph 0242; 0243; 0244; 0245
1H-Benzimidazole-5-methanol,1-methyl-(9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1H-Benzimidazole-5-methanol,1-methyl-(9CI) manufacturers
- Product
- 1H-Benzimidazole-5-methanol,1-methyl-(9CI) 115576-91-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- 1H-Benzimidazole-5-methanol,1-methyl-(9CI) 115576-91-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09