Imidazo[1,2-a]pyridine-2-carboxylic acid, 5,6,7,8-tetrahydro-
- Product Name
- Imidazo[1,2-a]pyridine-2-carboxylic acid, 5,6,7,8-tetrahydro-
- CAS No.
- 917364-11-5
- Chemical Name
- Imidazo[1,2-a]pyridine-2-carboxylic acid, 5,6,7,8-tetrahydro-
- Synonyms
- 5H,6H,7H,8H-iMidazo[1,2-a]pyridine-2-carboxylic acid;5,6,7,8-Tetrahydroimidazo[1,2-a]pyridine-2-carboxylic acid;Imidazo[1,2-a]pyridine-2-carboxylic acid, 5,6,7,8-tetrahydro-
- CBNumber
- CB41094194
- Molecular Formula
- C8H10N2O2
- Formula Weight
- 166.18
- MOL File
- 917364-11-5.mol
Imidazo[1,2-a]pyridine-2-carboxylic acid, 5,6,7,8-tetrahydro- Property
- Boiling point:
- 449.8±18.0 °C(Predicted)
- Density
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 1.68±0.20(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T796638
- Product name
- 5,6,7,8-Tetrahydroimidazo[1,2-A]pyridine-2-carboxylicAcid
- Packaging
- 250mg
- Price
- $265
- Updated
- 2021/12/16
- Product number
- W9509
- Product name
- 5,6,7,8-Tetrahydroimidazo[1,2-a]pyridine-2-carboxylicacid
- Packaging
- 250mg
- Price
- $187
- Updated
- 2021/12/16
- Product number
- OR951470
- Product name
- 5,6,7,8-Tetrahydro-imidazo[1,2-a]pyridine-2-carboxylicacid
- Purity
- 98%
- Packaging
- 250mg
- Price
- $196
- Updated
- 2021/12/16
- Product number
- 118916
- Product name
- 5,6,7,8-Tetrahydroimidazo-[1,2-a]pyridine-2-carboxylic acid
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $359
- Updated
- 2021/12/16
- Product number
- OR951470
- Product name
- 5,6,7,8-Tetrahydro-imidazo[1,2-a]pyridine-2-carboxylicacid
- Purity
- 98%
- Packaging
- 1g
- Price
- $508
- Updated
- 2021/12/16
Imidazo[1,2-a]pyridine-2-carboxylic acid, 5,6,7,8-tetrahydro- Chemical Properties,Usage,Production
Synthesis
64951-08-2
917364-11-5
The general procedure for the synthesis of 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxylic acid from imidazo[1,2-a]pyridine-2-carboxylic acid was carried out as follows: imidazo[1,2-a]pyridine-2-carboxylic acid (500 mg, 3.1 mmol) was dissolved in ethanol (20 mL) and platinum oxide (100 mg) was added as a catalyst. The reaction mixture was placed in an autoclave and hydrogenated under hydrogen pressure of 4 bar for overnight. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to dryness under reduced pressure to afford the white solid product 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxylic acid (500 mg, 97% yield). The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6) with the following characteristic peaks: δ 7.63 (s, 1H), 3.96 (t, 2H), 2.70 (t, 2H), 1.85 (m, 4H).
References
[1] Patent: WO2007/108750, 2007, A1. Location in patent: Page/Page column 77
[2] Patent: WO2006/135627, 2006, A2. Location in patent: Page/Page column 140
Imidazo[1,2-a]pyridine-2-carboxylic acid, 5,6,7,8-tetrahydro- Preparation Products And Raw materials
Raw materials
Preparation Products
Imidazo[1,2-a]pyridine-2-carboxylic acid, 5,6,7,8-tetrahydro- Suppliers
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