Dimethylenastron

Product Name: Dimethylenastron
CAS No.: 863774-58-7
Chemical Name: Dimethylenastron
Synonyms: enastron;Dimethylenastron;Eg5 Inhibitor III;Eg5 Inhibitor III(Dimethylenastron);Dimethylenastron - Eg5 inhibitor III;Inhibitor,Dimethylenastron,Kinesin,inhibit;Eg5 Inhibitor III, Dimethylenastron - CAS 863774-58-7 - Calbiochem;2,3,4,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-5(1H)-quinazolinone;4-(3-Hydroxyphenyl)-7,7-dimethyl-2-thioxo-2,3,4,6,7,8-hexahydroquinazolin-5(1H)-one;5(1H)-Quinazolinone, 2,3,4,6,7,8-hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-
CBNumber: CB41115853
Molecular Formula: C16H18N2O2S
Formula Weight: 302.39
MOL File: 863774-58-7.mol

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Dimethylenastron Property

Boiling point:: 475.6±55.0 °C(Predicted)
Density: 1.34±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: soluble15mg/mL, clear
pka: 9.59±0.10(Predicted)
form: powder
color: white to beige

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H360May damage fertility or the unborn child

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 324622
Product name: Eg5 Inhibitor III, Dimethylenastron
Packaging: 5mg
Price: $432
Updated: 2024/03/01

Sigma-Aldrich

Product number: 324622
Product name: Eg5 Inhibitor III, Dimethylenastron
Packaging: 1mg
Price: $154
Updated: 2023/01/07

Cayman Chemical

Product number: 22357
Product name: Dimethylenastron
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 22357
Product name: Dimethylenastron
Purity: ≥98%
Packaging: 5mg
Price: $109
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0905
Product name: Dimethylenastron
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $108
Updated: 2022/05/15

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Dimethylenastron Chemical Properties,Usage,Production

Uses

Dimethylnasetron is an inhibitor of mitotic motor kinesin Eg5, triggering apoptosis and upregulates Hsp-70 in human myeloma cells.

Biochem/physiol Actions

Dimethylenastron is specific, reversible inhibitor of the mitotic motor kinesin Eg5. Dimethylenastron inhibits bipolar spindle formation, and inhibits proliferation, migration and invasion of several pancreatic cancer cell lines in cell based assays.

storage

Store at -20°C

Dimethylenastron Preparation Products And Raw materials

Raw materials

Preparation Products

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Dimethylenastron Suppliers

Americas 1 China 50 Europe 1 India 2 Japan 1 United Kingdom 2 United States 11 Global 68

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2923
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94838
Advantage: 76

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28398
Advantage: 80

TCI Europe

Tel: 320-37350700
Fax: +32 (0)37350701
Email: sales@tcieurope.eu
Country: Europe
ProdList: 23680
Advantage: 75

TCI AMERICA

Tel: 800-4238616
Fax: +1-888-520-1075 / +1-503-283-1987
Email: sales@tciamerica.com
Country: Americas
ProdList: 23662
Advantage: 75

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4863
Advantage: 58

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4428
Advantage: 55

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2989
Advantage: 60

Shanghai JiYi Biotechnology Co. Ltd.

Tel: 13621943973
Fax: -
Email: sales@shjiyipharmatech.com
Country: China
ProdList: 1166
Advantage: 55

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View Lastest Price from Dimethylenastron manufacturers

Career Henan Chemical Co

Product: Dimethylenastron 863774-58-7
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2020-02-04

863774-58-7, DimethylenastronRelated Search:

SILICA Phenol Dimethylenastron

Dimethylenastron

2,3,4,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-5(1H)-quinazolinone

Eg5 Inhibitor III(Dimethylenastron)

Eg5 Inhibitor III, Dimethylenastron - CAS 863774-58-7 - Calbiochem

Dimethylenastron - Eg5 inhibitor III

Eg5 Inhibitor III

enastron

5(1H)-Quinazolinone, 2,3,4,6,7,8-hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-

4-(3-Hydroxyphenyl)-7,7-dimethyl-2-thioxo-2,3,4,6,7,8-hexahydroquinazolin-5(1H)-one

Inhibitor,Dimethylenastron,Kinesin,inhibit

863774-58-7