Dimethylenastron
- Product Name
- Dimethylenastron
- CAS No.
- 863774-58-7
- Chemical Name
- Dimethylenastron
- Synonyms
- enastron;Dimethylenastron;Eg5 Inhibitor III;Eg5 Inhibitor III(Dimethylenastron);Dimethylenastron - Eg5 inhibitor III;Inhibitor,Dimethylenastron,Kinesin,inhibit;Eg5 Inhibitor III, Dimethylenastron - CAS 863774-58-7 - Calbiochem;2,3,4,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-5(1H)-quinazolinone;4-(3-Hydroxyphenyl)-7,7-dimethyl-2-thioxo-2,3,4,6,7,8-hexahydroquinazolin-5(1H)-one;5(1H)-Quinazolinone, 2,3,4,6,7,8-hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-
- CBNumber
- CB41115853
- Molecular Formula
- C16H18N2O2S
- Formula Weight
- 302.39
- MOL File
- 863774-58-7.mol
Dimethylenastron Property
- Boiling point:
- 475.6±55.0 °C(Predicted)
- Density
- 1.34±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble15mg/mL, clear
- pka
- 9.59±0.10(Predicted)
- form
- powder
- color
- white to beige
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H360May damage fertility or the unborn child
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P391Collect spillage. Hazardous to the aquatic environment
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 324622
- Product name
- Eg5 Inhibitor III, Dimethylenastron
- Packaging
- 5mg
- Price
- $432
- Updated
- 2024/03/01
- Product number
- 324622
- Product name
- Eg5 Inhibitor III, Dimethylenastron
- Packaging
- 1mg
- Price
- $154
- Updated
- 2023/01/07
- Product number
- 22357
- Product name
- Dimethylenastron
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 22357
- Product name
- Dimethylenastron
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $109
- Updated
- 2024/03/01
- Product number
- SML0905
- Product name
- Dimethylenastron
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $108
- Updated
- 2022/05/15
Dimethylenastron Chemical Properties,Usage,Production
Uses
Dimethylnasetron is an inhibitor of mitotic motor kinesin Eg5, triggering apoptosis and upregulates Hsp-70 in human myeloma cells.
Biochem/physiol Actions
Dimethylenastron is specific, reversible inhibitor of the mitotic motor kinesin Eg5. Dimethylenastron inhibits bipolar spindle formation, and inhibits proliferation, migration and invasion of several pancreatic cancer cell lines in cell based assays.
storage
Store at -20°C
Dimethylenastron Preparation Products And Raw materials
Raw materials
Preparation Products
Dimethylenastron Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
View Lastest Price from Dimethylenastron manufacturers
- Product
- Dimethylenastron 863774-58-7
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-02-04