1-Acetyl-5-bromoindoline

Product Name: 1-Acetyl-5-bromoindoline
CAS No.: 22190-38-1
Chemical Name: 1-Acetyl-5-bromoindoline
Synonyms: BUTTPARK 75\04-10;1-ACETYL-5-BROMOINDOLINE;5-bromo-N-acetylindoline;1-ACETYL-5-BROMOINDOLINE 98%;1-Acetyl-5-bromoindoline,98%;1-Acetyl-5-bromoindoline,97%;1-(5-bromoindolin-1-yl)ethanone;1-(5-bromo-1-indolinyl)ethanone;1-ACETYL-5-BROMO-2,3-DIHYDROINDOLE;1-(5-Bromoindolin-1-yl)ethan-1-one
CBNumber: CB4114442
Molecular Formula: C10H10BrNO
Formula Weight: 240.1
MOL File: 22190-38-1.mol

More

Less

1-Acetyl-5-bromoindoline Property

Melting point:: 118-121°C
Boiling point:: 423.6±45.0 °C(Predicted)
Density: 1.529±0.06 g/cm3(Predicted)
storage temp.: -20°C
pka: 0.27±0.20(Predicted)
form: powder to crystal
color: White to Yellow to Orange
BRN: 165052
InChI: 1S/C10H10BrNO/c1-7(13)12-5-4-8-6-9(11)2-3-10(8)12/h2-3,6H,4-5H2,1H3
InChIKey: WQKQAIXOTCPWFE-UHFFFAOYSA-N
SMILES: CC(=O)N1CCc2cc(Br)ccc12
CAS DataBase Reference: 22190-38-1(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-52/53
Safety Statements: 26-36/37/39-61
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933998090
Storage Class: 11 - Combustible Solids

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A6125
Product name: 1-Acetyl-5-bromoindoline
Purity: ≥99%
Packaging: 1g
Price: $158
Updated: 2023/01/07

TCI Chemical

Product number: A2924
Product name: 1-Acetyl-5-bromoindoline
Purity: >98.0%(GC)
Packaging: 5g
Price: $90
Updated: 2025/07/31

TCI Chemical

Product number: A2924
Product name: 1-Acetyl-5-bromoindoline
Purity: >98.0%(GC)
Packaging: 25g
Price: $266
Updated: 2025/07/31

TRC

Product number: A192260
Product name: 1-Acetyl-5-bromoindoline
Packaging: 1g
Price: $90
Updated: 2021/12/16

Matrix Scientific

Product number: 058434
Product name: 1-Acetyl-5-bromoindoline
Packaging: 1g
Price: $48
Updated: 2021/12/16

More

Less

1-Acetyl-5-bromoindoline Chemical Properties,Usage,Production

Uses

1-Acetyl-5-bromoindoline is a valuable organic compound and could be used to synthesise 5-bromoindoline, 5-Bromo-7-nitroindoline, and others.

Synthesis

The synthesis method of 1-Acetyl-5-bromoindoline is as follows: add acetyl chloride (5.5 mmol, 1.1 equiv) to a stirred solution of 5-Bromoindolin (5 mmol, 1.0 equiv) and Et3N (7.5 mmol,1.5 equiv) in CH2Cl2 (15 mL) at 0°C. Stir the resulting mixture for 1 h under N2 atmosphere. Quench the reaction with NaHCO3 solution (20 mL). Separate the aqueous layer and wash with DCM (15 mL) and combine the organic layers. Dry the organicsolution over anhydrous Na2SO4 and evaporate under vacuum. Purify the residue by column chromatography on silica gel.

References

[1] ZHIYONG TAN*, WEI GUO*   Visible Light Mediated Chemoselective Hydroxylation of Benzylic Methylenes[J]. The Journal of Organic Chemistry, 2024, 89 4: 2656-2664. DOI:10.1021/acs.joc.3c02683.

1-Acetyl-5-bromoindoline Preparation Products And Raw materials

Raw materials

Acetyl chloride Triethylamine Indoline Bromine Dichloromethane Acetic acid 4-Dimethylaminopyridine

Preparation Products

More

Less

1-Acetyl-5-bromoindoline Suppliers

Americas 1 Belgium 1 China 89 Europe 1 France 1 Germany 2 India 6 Japan 1 Russia 1 Switzerland 3 The Netherlands 1 United Kingdom 10 United States 23 Global 140

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44802
Advantage: 61

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Shandong Xiya Chemical Co., Ltd

Tel: 13355009207 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

TCI Europe

Tel: 320-37350700
Fax: +32 (0)37350701
Email: sales@tcieurope.eu
Country: Europe
ProdList: 23671
Advantage: 75

TCI AMERICA

Tel: 800-4238616
Fax: +1-888-520-1075 / +1-503-283-1987
Email: sales@tciamerica.com
Country: Americas
ProdList: 23653
Advantage: 75

More

Less

View Lastest Price from 1-Acetyl-5-bromoindoline manufacturers

Career Henan Chemical Co

Product: 1-(5-Bromo-2,3-dihydro-1H-indol-1-yl)ethanone 22190-38-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200KG
Release date: 2020-01-09

22190-38-1, 1-Acetyl-5-bromoindolineRelated Search:

1-ACETYL-5-BROMOINDOLINE 5-BROMOINDOLINE 1-ACETYL-5-BROMO-7-NITROINDOLINE 5-Bromoindole Indoline AKOS BBS-00001025 1-(6-AMINO-5-BROMO-2,3-DIHYDRO-1H-INDOL-1-YL)ETHAN-1-ONE 1-ACETYL-5-BROMO-7-CHLOROINDOLINE 1-ACETYL-5-BROMO-7-IODOINDOLINE 1-ACETYL-5-BROMOINDOLIN-7-AMINE 1-acetyl-5-bromoindoline-2,3-dione BUTTPARK 11\07-57 SALOR-INT L338281-1EA BUTTPARK 148\07-54 1-Acetyl-5-bromo-1,2-dihydro-indol-3-one SALOR-INT L339164-1EA BUTTPARK 22\07-76 BUTTPARK 52\04-52

1-(5-BROMO-2,3-DIHYDRO-1H-INDOL-1-YL)ETHAN-1-ONE

1-ACETYL-5-BROMO-2,3-DIHYDROINDOLE

1-ACETYL-5-BROMOINDOLINE

1-acetyl-5-bromoindoline crystalline

1-Acetyl-5-bromoindoline,97%

BUTTPARK 75\04-10

1-Acetyl-5-bromoindoline,98%

1-ACETYL-5-BROMOINDOLINE 98%

1-(5-bromoindolin-1-yl)ethanone

1-(5-Bromo-2,3-dihydro-1H-indol-1-yl)ethan-1-one, 1-Acetyl-5-bromo-2,3-dihydro-1H-indole, 5-Bromo-2,3-dihydro-1-ethanoyl-1H-indole

1-(5-bromo-2,3-dihydroindol-1-yl)ethanone

1-(5-bromo-1-indolinyl)ethanone

1-(5-Bromo-2,3-dihydro-1H-indol-1-yl)ethanone

1-(5-Bromoindolin-1-yl)ethan-1-one

Ethanone, 1-(5-bromo-2,3-dihydro-1H-indol-1-yl)-

5-bromo-N-acetylindoline

1-(5-Bromoindolin-1-yl)ethan-1-one - [B93511]

22190-38-1

C10H10BORn

Indoles

Halogenated Heterocycles

Heterocyclic Building Blocks

Building Blocks

Halides

Pyrroles & Indoles

Halogenated Heterocycles

Heterocyclic Building Blocks

Indoles

IndolesBuilding Blocks