ChemicalBook > CAS DataBase List > (9S)-9-Amino-9-deoxoerythromycin

(9S)-9-Amino-9-deoxoerythromycin

Product Name
(9S)-9-Amino-9-deoxoerythromycin
CAS No.
26116-56-3
Chemical Name
(9S)-9-Amino-9-deoxoerythromycin
Synonyms
LY 024410;Brn 4241492;BRL 42852ER;Erythromycylamine;Erythromycilamine;9-()-Eythromyeyamine;9-Epierythromycylamine;Epierythromycyl-A-amine;9-(S)-AMINOERYTHROMYCIN;(9S)-erythromycyclamine
CBNumber
CB41236921
Molecular Formula
C37H70N2O12
Formula Weight
734.96
MOL File
26116-56-3.mol
More
Less

(9S)-9-Amino-9-deoxoerythromycin Property

Melting point:
123-127°C
Boiling point:
810.3±65.0 °C(Predicted)
Density 
1.19±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
DMF: 15 mg/ml; DMSO: 15 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml
form 
A solid
pka
13.41±0.70(Predicted)
color 
White to off-white
More
Less

Safety

Hazard Codes 
Xi,N
Risk Statements 
41-50/53
Safety Statements 
26-39-60-61
Toxicity
mouse,LD50,intraperitoneal,120mg/kg (120mg/kg),European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 13, Pg. 83, 1978.
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
28098
Product name
Erythromycylamine
Packaging
1mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
28098
Product name
Erythromycylamine
Packaging
10mg
Price
$903
Updated
2024/03/01
Cayman Chemical
Product number
28098
Product name
Erythromycylamine
Packaging
5mg
Price
$481
Updated
2024/03/01
Usbiological
Product number
257299
Product name
Erythromycylamine
Packaging
1mg
Price
$531
Updated
2021/12/16
TRC
Product number
E653400
Product name
Erythromycylamine
Packaging
10mg
Price
$1070
Updated
2021/12/16
More
Less

(9S)-9-Amino-9-deoxoerythromycin Chemical Properties,Usage,Production

Chemical Properties

(9S)-9-Amino-9-deoxoerythromycin is White Solid

Uses

(9S)-9-Amino-9-deoxoerythromycin is a semi-synthetic analogue of erythromycin prepared by reduction of erythromycin oxime. (9S)-9-Amino-9-deoxoerythromycin is a potent antibiotic, however the introduction of the amino- moiety increases the compound’s polarity and is disadvantageous for in vivo use. This limitation was overcome by the synthesis of dirithromycin, a Schiff base pro-drug that dissociates in vivo to erythromycylamine.

Uses

Erythromycylamine is a semi-synthetic analogue of erythromycin prepared by reduction of erythromycin oxime. Erythromycylamine is a potent antibiotic, however the introduction of the amino- moiety increases the compound’s polarity and is disadvantageous for in vivo use. This limitation was overcome by the synthesis of dirithromycin, a Schiff base pro-drug that dissociates in vivo to erythromycylamine.

Uses

(9S)-9-Amino-9-deoxoerythromycin is a metabolite of Dirithromycin; an antibiotic

Definition

ChEBI: A macrolide antibiotic that is erythromycin A in which the ketone group has been converted to the corresponding imine and then reduced to give the corresponding amino compound (the 9S diastereoisomer).

(9S)-9-Amino-9-deoxoerythromycin Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(9S)-9-Amino-9-deoxoerythromycin Suppliers

HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14332
Advantage
58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19553
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10404
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Medical Isotopes
Tel
--
Fax
--
Email
stohler@medicalisotopes.com
Country
United States
ProdList
6181
Advantage
68
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
More
Less

View Lastest Price from (9S)-9-Amino-9-deoxoerythromycin manufacturers

Career Henan Chemical Co
Product
(9S)-9-Amino-9-deoxoerythromycin 26116-56-3
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2019-12-25

26116-56-3, (9S)-9-Amino-9-deoxoerythromycinRelated Search:


  • (9S)-9-Amino-9-deoxoerythromycin
  • (9S)-9-amino-9-deoxyerythromycin
  • 9-Amino-9-deoxo-erythromycin, stereoisomer
  • 9-Epierythromycylamine
  • Brn 4241492
  • Epierythromycyl-A-amine
  • Erythromycin, 9-amino-9-deoxo-, (9S)- (9ci)
  • Erythromycin, 9-amino-9-deoxo-, stereoisomer
  • (9S)-9-AMiNA-9-deoxoerythroMycin
  • 9-(S)-AMINOERYTHROMYCIN
  • 9-(S)-ERYTHROMYCYLAMINE:9-AMINO-9-DEOXO-ERYTHROMYCIN
  • (9S)-9-Deoxy-9-aminoerythromycin A
  • (9S)-Erythromycylamine A
  • BRL 42852ER
  • Erythromycylamine
  • LY 024410
  • (9s)-9-aMino-9-deoxoeryhtroMycin
  • 9(S) ErythroMycylaMin A, BRL 42852ER, LY 024410
  • (9S)-erythromycyclamine
  • Dirithromycin EP impurity A
  • (9S)-9-Amino-9-deoxoerythromycin (9S)-9-Amino-9-deoxoerythromycin
  • Dirithromycin impurity A
  • Dirithromycin Impurity 1(Dirithromycin EP Impurity A)
  • Dirithromycin EP Impurity A/Erythromycylamine/(3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-10-amino-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimeth
  • Dirithromycin Impurit Ⅰ: (9S)-9-Amino-9-deoxoerythromycin
  • Erythromycilamine
  • Dirithromycin EP Impurity A (Erythromycylamine)
  • Erythromycin, 9-amino-9-deoxo-, (9S)-
  • Erythromycylamine (Dirithromycin EP Impurity A)
  • Erythromycylamine-13C-d3
  • (3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-10-Amino-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one
  • Erythromycylamine-13C-d3 (Dirithromycin EP Impurity A-13C-d3)
  • erythromyclamine, (9R)-isomer
  • (9S)-9-Amino-9-deoxoerythromycin (Dirithromycin Impurity)
  • 9-()-Eythromyeyamine
  • 26116-56-3
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Various Metabolites and Impurities