ChemicalBook > CAS DataBase List > 1,3-Dibromo-5-chlorobenzene

1,3-Dibromo-5-chlorobenzene

Product Name: 1,3-Dibromo-5-chlorobenzene
CAS No.: 14862-52-3
Chemical Name: 1,3-Dibromo-5-chlorobenzene
Synonyms: 1-CHLORO-3,5-DIBROMOBENZENE;3,5-DIBROMOCHLOROBENZENE;Fluralaner-045;oro-3,5-dibromobenzene;3-DibroMo-5-chlorobenzene;1,3-bromo-5-chlorobenzene;Phloroglucinol Impurity 57;1,3-DIBROMO-5-CHLOROBENZENE;3,5-Dibromo-1-chlorobenzene;Benzene, 1,3-dibromo-5-chloro-
CBNumber: CB4127709
Molecular Formula: C6H3Br2Cl
Formula Weight: 270.35
MOL File: 14862-52-3.mol

Less

1,3-Dibromo-5-chlorobenzene Property

Melting point:: 91-94 °C (lit.)
Boiling point:: 256 °C
Density: 2.021±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: soluble in Toluene
form: powder to crystal
color: White to Light yellow
InChI: InChI=1S/C6H3Br2Cl/c7-4-1-5(8)3-6(9)2-4/h1-3H
InChIKey: FNKCOUREFBNNHG-UHFFFAOYSA-N
SMILES: C1(Br)=CC(Cl)=CC(Br)=C1
CAS DataBase Reference: 14862-52-3(CAS DataBase Reference)

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
HS Code: 29039990

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 129127
Product name: 1-Chloro-3,5-dibromobenzene
Purity: 95%
Packaging: 5g
Price: $32.6
Updated: 2023/06/20

TCI Chemical

Product number: D3465
Product name: 1,3-Dibromo-5-chlorobenzene
Packaging: 5G
Price: $31
Updated: 2025/07/31

TCI Chemical

Product number: D3465
Product name: 1,3-Dibromo-5-chlorobenzene
Packaging: 25G
Price: $97
Updated: 2025/07/31

TRC

Product number: D425225
Product name: 1,3-Dibromo-5-chlorobenzene
Packaging: 5G
Price: $60
Updated: 2021/12/16

TRC

Product number: D425225
Product name: 1,3-Dibromo-5-chlorobenzene
Packaging: 1g
Price: $50
Updated: 2021/12/16

Less

1,3-Dibromo-5-chlorobenzene Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

1,3-Dibromo-5-chlorobenzene is a reactant in the preparation of orally bioavailable 1-(1H-indol-4-yl)-3,5-disubstituted benzene analogs as antimitotic agents.

Synthesis

626-39-1

14862-52-3

General procedure for the synthesis of 1,3-dibromo-5-chlorobenzene from 1,3,5-tribromobenzene: 1,3,5-tribromobenzene (9.44 g, 30 mmol) was dissolved in 120 mL of ethyl ether and cooled to -78 °C in a dry ice/acetone bath. Over 10 min, n-butyllithium (13.2 mL of a 2.5 M hexane solution, 33 mmol) was added slowly and dropwise. The reaction mixture was continued to be stirred at -78 °C for 10 min, followed by the addition of hexachloroethane (7.15 g, 30.2 mmol) in batches over 3 min. After addition, the reaction mixture was stirred at -78 °C for 15 minutes, then brought to room temperature and stirred for 3.2 hours. Upon completion of the reaction, the mixture was transferred to a dispensing funnel and partitioned by adding 100 mL of water and 100 mL of ethyl acetate. The aqueous layer was separated and extracted with another 100 mL of ethyl acetate. The organic layers were combined, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give the light brown solid product 1,3-dibromo-5-chlorobenzene (7.72 g, 95% yield). The product was characterized by 1H NMR (CDCl3, 300 MHz): δ 7.57 (t, 1H), 7.47 (d, 2H).

References

[1] Patent: EP1208091, 2006, B1. Location in patent: Page/Page column 23
[2] Journal of Medicinal Chemistry, 2006, vol. 49, # 2, p. 727 - 739
[3] Tetrahedron Letters, 1997, vol. 38, # 9, p. 1559 - 1562

1,3-Dibromo-5-chlorobenzene Preparation Products And Raw materials

Raw materials

Preparation Products

Less

1,3-Dibromo-5-chlorobenzene Suppliers

Americas 1 Belgium 1 China 302 Europe 3 France 2 Germany 4 India 9 Japan 3 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 9 United States 27 Global 365

Shanghai Harvest Chemical Industrial Co., Ltd.

Tel: 021-31038972,31038973 17321035817
Fax: +86-21-51385350
Email: sales@harvest-chem.com
Country: China
ProdList: 2816
Advantage: 64

Tocopharm Co., Ltd.

Tel: +86-021-69895597 13776836200 +86-13776836200
Fax: 021-61292409
Email: tocopharm@gmail.com
Country: China
ProdList: 196
Advantage: 55

Changzhou Carman Chemical Co., ltd

Tel: 0519-0519-83534936 18151214939
Email: 1521178147@qq.com
Country: China
ProdList: 497
Advantage: 58

Sanjing New Materials Technology (Taizhou) Co., Ltd.

Tel: 15250805028
Fax: QQ：1048979734
Email: 1048979734@qq.com
Country: China
ProdList: 339
Advantage: 58

Shanghai Finechem Biotechnology Co., Ltd.

Tel: 15821337685
Email: hwh-chem@163.com
Country: China
ProdList: 98
Advantage: 58

FUXIN QINGJISHENG SCIENCE AND TECHNOLOGY CO.,LID

Tel: 13365798276
Email: hxy696128@126.com
Country: China
ProdList: 484
Advantage: 58

Nantong Haochun Biotechnology Co., Ltd

Tel: 0513-88562884 15162883737
Email: 425424481@qq.com
Country: China
ProdList: 65
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 2805
Advantage: 65

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Puyang Huicheng Electronic Material Co. Ltd.

Tel: 0393-0393-0393-8910800 15039333257
Fax: 0393-8912775
Email: info@huichengchem.com
Country: China
ProdList: 569
Advantage: 64

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527621225
Email: 1791901229@qq.com
Country: China
ProdList: 6945
Advantage: 52

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Aemon Chemical

Tel: 0086-755-86198205
Email: acinfo@aemonchem.com
Country: China
ProdList: 1931
Advantage: 57

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11707
Advantage: 57

Springchem New Material Technology Co.,Limited

Tel: +86-021-62885108 +8613917661608
Email: info@spring-chem.com
Country: China
ProdList: 2068
Advantage: 57

Shanghai Sphchem Co., Ltd.

Tel: 021-56491756 13512199871
Fax: 021-5649-1756
Email: 2819742715@qq.com
Country: China
ProdList: 4000
Advantage: 55

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Shanghai Topbiochem Technology Co., Ltd

Tel: +86-21-60341587
Fax: +86-21-61294319
Email: sales@topbiochem.com
Country: China
ProdList: 6175
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 150-2103-5486 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9342
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9546
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

Anichem Inc.

Tel: 0512-69369885
Fax: 0512-69369880
Email: sales@anichem.com.cn
Country: China
ProdList: 495
Advantage: 55

Shanghai Hong-chuang Pharma Tech Co., Ltd.

Tel: 18151128828
Fax: -
Email: hc-sales@foxmail.com
Country: China
ProdList: 2647
Advantage: 55

Aloespharm Co., Ltd.

Tel: 021-20960837
Fax: 021-20960837
Email: market@aloespharm.com
Country: China
ProdList: 1302
Advantage: 55

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9979
Advantage: 55

Huainan Kedi Chemical Factory

Tel: 0554-2106669
Fax: 0554-2666215
Email: sales1@kedichem.com
Country: China
ProdList: 4924
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Country: China
ProdList: 2930
Advantage: 58

Shanghai Worldyang Chemical Co.,Ltd.

Tel: 021-021-56795766
Fax: +86-21-56795266
Email: sales@worldyachem.com
Country: China
ProdList: 9476
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18333
Advantage: 56

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13350
Advantage: 58

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Credit-Chem Co., Ltd.

Tel: 400-821-5857 021-64326257
Fax: 021-64393586 QQ;2798200800
Email: credit-chem@foxmail.com
Country: China
ProdList: 5219
Advantage: 58

Tianjin Anhao Biological Technology Co., Ltd.

Tel
Email: sales@ahpharmatech.com
Country: China
ProdList: 5734
Advantage: 55

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

Less

View Lastest Price from 1,3-Dibromo-5-chlorobenzene manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 1,3-Dibromo-5-chlorobenzene 14862-52-3
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5tons
Release date: 2024-12-03

Speranza Chemical Co., Ltd.

Product: 3,5-Dibromochlorobenzene 14862-52-3
Price: US $150.00/KG
Min. Order: 1KG
Purity: 98%+
Supply Ability: 300MT/year
Release date: 2019-12-24

Henan Aochuang Chemical Co.,Ltd.

Product: 1,3-Dibromo-5-chlorobenzene 14862-52-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-08

14862-52-3, 1,3-Dibromo-5-chlorobenzeneRelated Search:

2,4-DIBROMOBIPHENYL 3,5-Dibromo-4-hydroxybenzaldehyde 1,2-Dibromopropane 1,2,4-Trichlorobenzene Chlorobenzene 1,3-Dibromo-5,5-dimethylhydantoin 2,2-Bis(bromomethyl)propane-1,3-diol 1,2,3-Trichlorobenzene Difluorochloromethane 4,6-DIBROMO-2,3-DICHLOROANILINE 2,6-Dibromo-4-chloroaniline 2-CHLORO-4,6-DIBROMOANILINE 2,6-DIBROMO-4-CHLORO-3,5-DIMETHYLPHENOL 2,6-DIBROMO-4-CHLOROPHENOL 2-AMINO-3,5-DIBROMO-6-CHLOROBENZOIC ACID 1,4-DIBROMO-2-CHLOROBENZENE,1,4-Dibromo-2-chlorobenzene, 99+% 1,3-DIBROMO-2,5-DICHLOROBENZENE 3,5-DIBROMO-1,2-DICHLOROBENZENE

1-CHLORO-3,5-DIBROMOBENZENE

3,5-DIBROMOCHLOROBENZENE

1,3-DIBROMO-5-CHLOROBENZENE

1-CHLORO-3,5-DIBROMOBENZENE, RECRYSTALLISED GRADE

1-Chloro-3,5-dibromobenzene,97%

3-DibroMo-5-chlorobenzene

1,3-DibroMo-5-chlorobenzene[3,5-DibroMochlorobenzene]

1,3-Dibromo-5-chlorobenzene&gt

oro-3,5-dibromobenzene

Benzene, 1,3-dibromo-5-chloro-

1,3-Dibromo-5-chlorobenzene ISO 9001：2015 REACH

Fluralaner-045

1,3-bromo-5-chlorobenzene

Phloroglucinol Impurity 57

3,5-Dibromo-1-chlorobenzene

14862-52-3

14862-52-1

C6H3Br2C1

Br2C6H3Cl

Building Blocks

Halogenated Hydrocarbons

Organic Building Blocks

Aryl

Benzene derivatives

Aryl

Halogenated Hydrocarbons

Miscellaneous

Bromine Compounds

Chlorine Compounds

Aromatic Halides (substituted)

API intermediates