4-SULFAMOYLPHENYLBORONIC ACID, PINACOL ESTER

Product Name: 4-SULFAMOYLPHENYLBORONIC ACID, PINACOL ESTER
CAS No.: 214360-51-7
Chemical Name: 4-SULFAMOYLPHENYLBORONIC ACID, PINACOL ESTER
Synonyms: 4-Boronobenzenesulfonamide,pinacol ester;4-SULFAMOYLPHENYLBORONIC ACID, PINACOL ESTER;4-Sulfamoylbenzeneboronic acid, pinacol ester;4-Sulphamoylbenzeneboronic acid, pinacol ester;BENZENESULFONAMIDE-4-BORONIC ACID PINACOL ESTER;Benzenesulfonamide-4-boronic acid pinacol ester ,98%;4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonamide;4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfon...;4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)benzenesulfonamide;4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulphonamide
CBNumber: CB4127800
Molecular Formula: C12H18BNO4S
Formula Weight: 283.15
MOL File: 214360-51-7.mol

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4-SULFAMOYLPHENYLBORONIC ACID, PINACOL ESTER Property

Boiling point:: 427.1±47.0 °C(Predicted)
Density: 1.24±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 10.00±0.10(Predicted)
form: solid
color: Off-white to light yellow
InChI: InChI=1S/C12H18BNO4S/c1-11(2)12(3,4)18-13(17-11)9-5-7-10(8-6-9)19(14,15)16/h5-8H,1-4H3,(H2,14,15,16)
InChIKey: XDDLLUBKOZYOMY-UHFFFAOYSA-N
SMILES: C1(S(N)(=O)=O)=CC=C(B2OC(C)(C)C(C)(C)O2)C=C1

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Safety

HS Code: 2931900090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: S699055
Product name: 4-SulfamoylphenylboronicAcidPinacolEster
Packaging: 1g
Price: $120
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB160465
Product name: 4-Boronobenzenesulfonamide, pinacol ester
Packaging: 500mg
Price: $125
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB160465
Product name: 4-Boronobenzenesulfonamide, pinacol ester
Packaging: 250mg
Price: $80
Updated: 2021/12/16

SynQuest Laboratories

Product number: 8H69-1-Y3
Product name: 4-Sulfamoylbenzeneboronic acid, pinacol ester
Purity: 98%
Packaging: 500mg
Price: $96
Updated: 2021/12/16

Matrix Scientific

Product number: 121936
Product name: 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonamide
Purity: >95%
Packaging: 1g
Price: $162
Updated: 2021/12/16

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4-SULFAMOYLPHENYLBORONIC ACID, PINACOL ESTER Chemical Properties,Usage,Production

Uses

4-SULFAMOYLPHENYLBORONIC ACID, PINACOL ESTER is used for preparation of Valdecoxib.

Synthesis

Potassium acetate (2.5 g, 24.4 mmol) was added to a solution of 4-bromobenzenesulfonamide (2.00 g, 9.32 mmol) and bis(pinacolato)diboron (2.40 g, 9.32 mmol) in DMSO (20 mL) and the mixture was degassed for 45 minutes. Then [1,1'-bis(diphenylphosphino)ferrocene]dichloropalladium(II) (220 mg, 0.26 mmol) was added and the mixture was heated to 90C for 16 hours. Once cooled, the reaction mixture was diluted with EtOAc (30 mL), washed with water (3 x 30 mL), dried over MgSO4 and concentrated under vacuum. The residue was ground from Et2O (50 mL) and HCl (1 M, 50 mL), and the solid formed was dissolved in CH2Cl2 (30 mL) and filtered through a silica gel pad washed with Et2O, followed by concentration to give phenylsulfonamide-4-boronic acid as an off-white solid, 13% yield, 550 mg.

4-SULFAMOYLPHENYLBORONIC ACID, PINACOL ESTER Preparation Products And Raw materials

Raw materials

Pinacol Ammonium hydroxide Ethanol Toluene Tetrahydrofuran Dichloromethane Triisopropyl borate 4-Bromobenzenesulfonyl chloride Ammonium carbonate n-Butyllithium

Preparation Products

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4-SULFAMOYLPHENYLBORONIC ACID, PINACOL ESTER Suppliers

Canada 1 China 73 Germany 1 India 2 United Kingdom 2 United States 12 Global 91

J & K SCIENTIFIC LTD.

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Shanghai Topbiochem Technology Co., Ltd

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214360-51-7, 4-SULFAMOYLPHENYLBORONIC ACID, PINACOL ESTERRelated Search:

2-Boronobenzenesulfonamide (3-AMINOSULPHONYL)BENZENEBORONIC ACID 4-(Aminosulfonyl)phenylboronic acid BENZENESULFONAMIDE-3-BORONIC ACID PINACOL ESTER 4-(PYRROLIDINE-1-SULFONYL)PHENYLBORONIC ACID, PINACOL ESTER 4-(N,N-Dimethylaminosulfonyl)phenylboronic acid pinacol ester N-METHYL-4-BENZENESULFONAMIDEBORONIC ACID PINACOL ESTER 4-(TERT-BUTYLAMINO)SULFONYLPHENYLBORONIC ACID PINACOL ESTER 4-(N-CYCLOPROPYLSULFONAMIDE)PHENYLBORONIC ACID PINACOL ESTER 4-SULFAMOYLPHENYLBORONIC ACID, PINACOL ESTER

4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)benzenesulfonamide

4-SULFAMOYLPHENYLBORONIC ACID, PINACOL ESTER

BENZENESULFONAMIDE-4-BORONIC ACID PINACOL ESTER

4-Boronobenzenesulfonamide,pinacol ester

Benzenesulfonamide-4-boronic acid pinacol ester ,98%

4-Sulphamoylbenzeneboronic acid, pinacol ester

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulphonamide

3-hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-sulfamoylphenyl)boronate

4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonamide

4-Sulfamoylbenzeneboronic acid, pinacol ester

Benzenesulfonamide, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfon...

214360-51-7

C12H20BNO5S

Amines

Boron Derivatives

Intermediates

Intermediates & Fine Chemicals

Pharmaceuticals

Sulfur & Selenium Compounds

Aryl

Organoborons

Sulfonamide