2-Benzothiazolamine,7-chloro-(9CI)
- Product Name
- 2-Benzothiazolamine,7-chloro-(9CI)
- CAS No.
- 20358-01-4
- Chemical Name
- 2-Benzothiazolamine,7-chloro-(9CI)
- Synonyms
- 2-Amino-7-chlor-benzthiazol;2-Amino-7-chlorobenzothiazol;7-Chlorobenzothiazol-2-amine;2-Amino-7-chlorobenzothiazole;2-Benzothiazolamine, 7-chloro-;7-Chloro-benzothiazol-2-ylamine;7-Chlorobenzo[d]thiazol-2-aMine;7-Chlorobenzo[d]thiazole-2-amine;7-Chloro-1,3-benzothiazol-2-amine;2-Benzothiazolamine,7-chloro-(9CI)
- CBNumber
- CB41301416
- Molecular Formula
- C7H5ClN2S
- Formula Weight
- 184.65
- MOL File
- 20358-01-4.mol
2-Benzothiazolamine,7-chloro-(9CI) Property
- Melting point:
- 177-178 °C(Solv: ethanol (64-17-5))
- Boiling point:
- 344.3±34.0 °C(Predicted)
- Density
- 1.532±0.06 g/cm3(Predicted)
- storage temp.
- RT, protect from light
- pka
- 2.68±0.30(Predicted)
- Appearance
- Light yellow to light brown Solid
Safety
- HS Code
- 29342000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 301202
- Product name
- 7-Chlorobenzo[d]thiazol-2-amine
- Packaging
- 250.00mg
- Price
- $80
- Updated
- 2026/05/19
- Product number
- 301202
- Product name
- 7-Chlorobenzo[d]thiazol-2-amine
- Packaging
- 1.00g
- Price
- $158
- Updated
- 2026/05/19
- Product number
- 301202
- Product name
- 7-Chlorobenzo[d]thiazol-2-amine
- Packaging
- 5.00g
- Price
- $498
- Updated
- 2026/05/19
- Product number
- CD11168917
- Product name
- 7-Chlorobenzo[d]thiazol-2-amine
- Purity
- 95+%
- Packaging
- 5g
- Price
- $594
- Updated
- 2026/05/26
- Product number
- CD11168917
- Product name
- 7-Chlorobenzo[d]thiazol-2-amine
- Purity
- 95+%
- Packaging
- 10g
- Price
- $950
- Updated
- 2026/05/26
2-Benzothiazolamine,7-chloro-(9CI) Chemical Properties,Usage,Production
Synthesis
4947-89-1
20358-00-3
20358-01-4
General procedure for the synthesis of 2-amino-5-chlorobenzothiazole and 7-chlorobenzo[d]thiazol-2-amine from 3-chlorobenzothiourea: 3-chlorobenzothiourea (105 mg, 0.56 mmol) was dissolved in 10 mL of acetic acid. Benzyltrimethylammonium tribromide (329 mg, 0.84 mmol) was added and the reaction mixture was stirred at room temperature for 14 hours. After completion of the reaction, the acetic acid was removed by distillation under reduced pressure. The residue was redissolved in 15 mL of dichloromethane (DCM) and 10 mL of 0.5 N aqueous sodium hydroxide was added. The aqueous phase was extracted with dichloromethane (2 x 15 mL). The organic layers were combined, filtered through a phase separator and concentrated under reduced pressure to remove the solvent. The crude product was purified by fast column chromatography using pentane-ethyl acetate (12:5) as eluent to afford the target product 2-amino-5-chlorobenzothiazole (61 mg, 59% yield) as a white solid. The structure of the product was analyzed by 1H NMR (500 MHz, CD3OD) δ 7.05 (dd, J = 8.4, 2.0 Hz, 1H), 7.35 (d, J = 2.0 Hz, 1H), 7.53 (d, J = 8.4 Hz, 1H); 13C NMR (125 MHz, CD3OD) δ 117.41, 121.45, 121.60 129.37, 131.55, 153.24, 170.04; Mass Spectrometry (ESI): m/z 185 [M + H]+ confirmed.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 14, p. 4839 - 4843
[2] Yakugaku Zasshi, 1957, vol. 77, p. 649,651
[3] Chem.Abstr., 1957, p. 16435
2-Benzothiazolamine,7-chloro-(9CI) Preparation Products And Raw materials
Raw materials
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