4-Chlorobenzonitrile
- Product Name
- 4-Chlorobenzonitrile
- CAS No.
- 623-03-0
- Chemical Name
- 4-Chlorobenzonitrile
- Synonyms
- PCBN;AKOS B004081;Thymidine 50-89-5;Chlorobenzonitrile;p-Chlorbenzonitril;P-CHLORBENZONITRILE;p-Chlorotolunitrile;P-CHLOROBENZONITRILE;4-Chlorocyanobenzene;4-CHLOROBENZONITRILE
- CBNumber
- CB4130147
- Molecular Formula
- C7H4ClN
- Formula Weight
- 137.57
- MOL File
- 623-03-0.mol
4-Chlorobenzonitrile Property
- Melting point:
- 90-93 °C(lit.)
- Boiling point:
- 223 °C(lit.)
- Density
- 1,2 g/cm3
- vapor pressure
- 6.67hPa at 80.4℃
- refractive index
- 1.4530 (estimate)
- Flash point:
- 108 °C
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- 0.245g/l practically insoluble
- form
- Flakes or Chunks
- color
- White to yellow
- Water Solubility
- insoluble
- BRN
- 1072122
- InChIKey
- GJNGXPDXRVXSEH-UHFFFAOYSA-N
- LogP
- 2.47 at 20℃
- CAS DataBase Reference
- 623-03-0(CAS DataBase Reference)
- NIST Chemistry Reference
- 4-Chlorobenzoic acid nitrile(623-03-0)
- EPA Substance Registry System
- 4-Chlorobenzonitrile (623-03-0)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/22-36/37/38
- Safety Statements
- 23-26-36
- RIDADR
- 3439
- WGK Germany
- 2
- RTECS
- DI2800000
- Hazard Note
- Harmful
- TSCA
- TSCA listed
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29269095
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 115622
- Product name
- 4-Chlorobenzonitrile
- Purity
- 99%
- Packaging
- 25g
- Price
- $63.07
- Updated
- 2025/07/31
- Product number
- 115622
- Product name
- 4-Chlorobenzonitrile
- Purity
- 99%
- Packaging
- 100g
- Price
- $314
- Updated
- 2025/07/31
- Product number
- C0135
- Product name
- 4-Chlorobenzonitrile
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $22
- Updated
- 2025/07/31
- Product number
- C0135
- Product name
- 4-Chlorobenzonitrile
- Purity
- >98.0%(GC)
- Packaging
- 500g
- Price
- $171
- Updated
- 2025/07/31
- Product number
- C427640
- Product name
- 4-Chlorobenzonitrile
- Packaging
- 2.5g
- Price
- $60
- Updated
- 2021/12/16
4-Chlorobenzonitrile Chemical Properties,Usage,Production
Chemical Properties
4-Chlorobenzonitrile [623-03-0], 4- chloro-1-cyanobenzene, Cl – C6H4 – CN, Mr 137.6, mp 97℃, forms colorless crystals that can be sublimed. The compound is steam volatile, readily soluble in organic solvents, and only sparingly soluble in water. 4-Chlorobenzonitrile is produced industrially by the ammoxidation of 4-chlorotoluene. It is used in the synthesis of a red pigment for plastics.
Uses
4-Chlorobenzonitrile is used to prepare a red pigment for plastics. It is also used in the preparation of amides in organic synthesis. Further, it is used as an intermediate of dye and active pharmaceutical ingredients.
Definition
ChEBI: 4-Chlorobenzonitrile is a member of benzenes and a nitrile.
Synthesis Reference(s)
The Journal of Organic Chemistry, 23, p. 1350, 1958 DOI: 10.1021/jo01103a031
Synthetic Communications, 19, p. 1431, 1989 DOI: 10.1080/00397918908054553
Tetrahedron Letters, 31, p. 1063, 1990 DOI: 10.1016/S0040-4039(00)94431-9
Flammability and Explosibility
Non flammable
Synthesis
224 grams of V2O5 was added to a solution consisting of 490 ml of water 468 grams of oxalic acid at a temperature of 80 to 90??C, stirred thoroughly, and reacted to obtain a vanadium oxalate solution.
1250 g of SiO2 silica sol at a weight percent concentration of 40% SiO2 was slowly added to the above solution under stirring, and then a solution comprising 864 g of Cr(NO3)3-9H2O, 12.4 g of KNO3 and 500 ml of water, 76.4 g of H3BO3, 85.1 g of 85% phosphoric acid and 500 ml of water and 43.5 g of (NH4)6Mo7O24-4H2O and 100 ml of water were composed of a solution, stirred, heated and evaporated to a solid content of 40% by weight to obtain a viscous slurry.
After the above slurry was formed by spray drying, the catalyst precursor was pre-roasted at 300??C for 2 hrs, and then roasted at 650??C for 5 hrs to obtain a catalyst composed of atomic ratio: V1.00Cr0.9B0.50P0.30Mo0.10K0.05/SiO2, and the catalyst main loading weight ratio was 50/50.
Property Evaluation of Catalyst Processes Conditions: p-chlorotoluene: ammonia: air = 1:4:25 (molar), catalyst weight loading (WWH) 0.05 h-1, reaction temperature 420 ??, reaction pressure 0.01 MPa.
Results: p-chlorotoluene conversion 99.6% p-chlorobenzonitrile selectivity 91.5 %, p-chlorobenzonitrile conversion 99.6% p-chlorobenzonitrile selectivity 91.5% p-chlorobenzonitrile conversion 99.6% p-chlorobenzonitrile conversion. nbsp;91.5% p-chlorobenzonitrile yield 91.1%.
4-Chlorobenzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Chlorobenzonitrile manufacturers
- Product
- 4-Chlorobenzonitrile 623-03-0
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 20tons
- Release date
- 2025-08-21
- Product
- 4-Chlorobenzonitrile 623-03-0
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5tons
- Release date
- 2024-12-05
- Product
- 4-Chlorobenzonitrile 623-03-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-18