4-Chlorobenzene-1-carboximidamide hydrochloride

Product Name: 4-Chlorobenzene-1-carboximidamide hydrochloride
CAS No.: 14401-51-5
Chemical Name: 4-Chlorobenzene-1-carboximidamide hydrochloride
Synonyms: 4-CHLOROBENZAMIDINE HCL;4-Chlorobenzimidamide HCl;p-chloro-benzamidhydrochloride;4-chlorbenamidine hydrochloride;4-CHLORO-BENZAMIDINE HYDROCHLORIDE;4-chlorobenzimidamide hydrochloride;4-ChlorobenzamidineHydrochloride>p-chloro-benzamidinmonohydrochloride;4-Chlorobenzene-1-carboximidamideHCl;4-Chlorobenzamidine hydrochloride ,95%
CBNumber: CB7404210
Molecular Formula: C7H8Cl2N2
Formula Weight: 191.06
MOL File: 14401-51-5.mol

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4-Chlorobenzene-1-carboximidamide hydrochloride Property

Melting point:: 244 °C
storage temp.: Inert atmosphere,Room Temperature
form: powder to crystal
color: White to Almost white
CAS DataBase Reference: 14401-51-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,T
Risk Statements: 36/37/38-43-36-25
Safety Statements: 26-36-37/39-45-36/37
RTECS: CV6136200
Hazard Note: Irritant
HS Code: 29252900
Toxicity: mouse,LD50,intravenous,90mg/kg (90mg/kg),Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 16, 1945.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: C3090
Product name: 4-Chlorobenzamidine Hydrochloride
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $60
Updated: 2025/07/31

TCI Chemical

Product number: C3090
Product name: 4-Chlorobenzamidine Hydrochloride
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $197
Updated: 2025/07/31

TRC

Product number: C428340
Product name: 4-Chlorobenzene-1-carboximidamidehydrochloride
Packaging: 250mg
Price: $55
Updated: 2021/12/16

Oakwood

Product number: 049070
Product name: 4-Chlorobenzamidine Hydrochloride
Purity: 98%
Packaging: 1g
Price: $10
Updated: 2021/12/16

AK Scientific

Product number: J92838
Product name: 4-Chlorobenzamidine Hydrochloride
Packaging: 1g
Price: $12
Updated: 2021/12/16

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4-Chlorobenzene-1-carboximidamide hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

4-Chlorobenzene-1-carboximidamide, HCl

Synthesis

623-03-0

14401-51-5

The general procedure for the synthesis of 4-chlorobenzamidine hydrochloride from p-chlorobenzonitrile was as follows: a THF solution of 1 M LiHMDS (22 mmol) was added to a dry 50 mL reaction flask, followed by the addition of a 2 mL THF solution of p-chlorobenzonitrile (2.76 g, 20.0 mmol). The reaction mixture was stirred at room temperature for 4 hours. Upon completion of the reaction, 5-6N HCl (in isopropanol, 15 mL) was added. The crude reaction mixture was placed at 0°C overnight. The precipitated product was collected by filtration and washed with ether to give 3.5 g (93% yield) of 4-chlorobenzamidine hydrochloride as a white solid with a melting point of 205 °C (literature value: 243-245 °C) (E. Ragona, D. L. Nelson, M. Mares-Guis, J. Amer. Chem. Soc. EPO 1975,97,. 6844-6848). - IR (KBr): ν = 3239, 3054, 1678, 1460, 1401, 1036, 715 cm-1. - 1H NMR (250 MHz, [D6] DMSO): δ = 7.60-7.77 (m, 2H), 7.85-7.97 (m, 2H), 8.4 (br.s, 3H, NH). - 13C NMR (62.9 MHz, [D6] DMSO): δ = 126.79 (Cquat), 129.36 (+), 130.57 (+), 139.1 (Cquat), 165.1 (NCN).

References

[1] European Journal of Organic Chemistry, 2006, # 12, p. 2753 - 2765
[2] Patent: WO2006/94604, 2006, A1. Location in patent: Page/Page column 62; 63; 72; 73
[3] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 17, p. 5235 - 5246
[4] Journal of the American Chemical Society, 1985, vol. 107, # 9, p. 2743 - 2748
[5] Patent: US6218538, 2001, B1

4-Chlorobenzene-1-carboximidamide hydrochloride Preparation Products And Raw materials

Raw materials

4-Chlorobenzonitrile Sodium Ammonium chloride Methanol

Preparation Products

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4-Chlorobenzene-1-carboximidamide hydrochloride Suppliers

Americas 1 Belgium 2 Canada 2 China 113 Egypt 1 Europe 1 Germany 6 India 5 Japan 1 Poland 1 Switzerland 1 United Kingdom 15 United States 41 Global 190

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View Lastest Price from 4-Chlorobenzene-1-carboximidamide hydrochloride manufacturers

Honest Joy Holdings Limited

Product: 4-Chlorobenzene-1-carboximidamide, HCl 14401-51-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99.3%
Supply Ability: 100 tons
Release date: 2022-01-26

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-Chlorobenzene-1-carboximidamide hydrochloride 14401-51-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: 4-Chlorobenzene-1-carboximidamide hydrochloride 14401-51-5
Price: US $8.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10MT
Release date: 2018-12-17

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4-Chlorobenzimidamide HCl

14401-51-5

C7H7ClN2ClH

C7H7ClN2HCl

pharmacetical