ChemicalBook > CAS DataBase List > 4-Chlorobenzene-1-carboximidamide hydrochloride

4-Chlorobenzene-1-carboximidamide hydrochloride

Product Name
4-Chlorobenzene-1-carboximidamide hydrochloride
CAS No.
14401-51-5
Chemical Name
4-Chlorobenzene-1-carboximidamide hydrochloride
Synonyms
4-CHLOROBENZAMIDINE HCL;4-Chlorobenzimidamide HCl;p-chloro-benzamidhydrochloride;4-chlorbenamidine hydrochloride;4-CHLORO-BENZAMIDINE HYDROCHLORIDE;4-chlorobenzimidamide hydrochloride;4-ChlorobenzamidineHydrochloride>p-chloro-benzamidinmonohydrochloride;4-Chlorobenzene-1-carboximidamideHCl;4-Chlorobenzamidine hydrochloride ,95%
CBNumber
CB7404210
Molecular Formula
C7H8Cl2N2
Formula Weight
191.06
MOL File
14401-51-5.mol
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4-Chlorobenzene-1-carboximidamide hydrochloride Property

Melting point:
244 °C
storage temp. 
Inert atmosphere,Room Temperature
form 
powder to crystal
color 
White to Almost white
CAS DataBase Reference
14401-51-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,T
Risk Statements 
36/37/38-43-36-25
Safety Statements 
26-36-37/39-45-36/37
RTECS 
CV6136200
Hazard Note 
Irritant
HS Code 
29252900
Toxicity
mouse,LD50,intravenous,90mg/kg (90mg/kg),Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 16, 1945.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
C3090
Product name
4-Chlorobenzamidine Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$60
Updated
2025/07/31
TCI Chemical
Product number
C3090
Product name
4-Chlorobenzamidine Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$197
Updated
2025/07/31
TRC
Product number
C428340
Product name
4-Chlorobenzene-1-carboximidamidehydrochloride
Packaging
250mg
Price
$55
Updated
2021/12/16
Matrix Scientific
Product number
075696
Product name
4-Chlorobenzene-1-carboximidamide hydrochloride
Purity
95+%
Packaging
1g
Price
$59
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC35805
Product name
4-Chloro-benzamidine hydrochloride
Packaging
1g
Price
$59.6
Updated
2021/12/16
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4-Chlorobenzene-1-carboximidamide hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

4-Chlorobenzene-1-carboximidamide, HCl

Synthesis

623-03-0

14401-51-5

The general procedure for the synthesis of 4-chlorobenzamidine hydrochloride from p-chlorobenzonitrile was as follows: a THF solution of 1 M LiHMDS (22 mmol) was added to a dry 50 mL reaction flask, followed by the addition of a 2 mL THF solution of p-chlorobenzonitrile (2.76 g, 20.0 mmol). The reaction mixture was stirred at room temperature for 4 hours. Upon completion of the reaction, 5-6N HCl (in isopropanol, 15 mL) was added. The crude reaction mixture was placed at 0°C overnight. The precipitated product was collected by filtration and washed with ether to give 3.5 g (93% yield) of 4-chlorobenzamidine hydrochloride as a white solid with a melting point of 205 °C (literature value: 243-245 °C) (E. Ragona, D. L. Nelson, M. Mares-Guis, J. Amer. Chem. Soc. EPO 1975,97,. 6844-6848). - IR (KBr): ν = 3239, 3054, 1678, 1460, 1401, 1036, 715 cm-1. - 1H NMR (250 MHz, [D6] DMSO): δ = 7.60-7.77 (m, 2H), 7.85-7.97 (m, 2H), 8.4 (br.s, 3H, NH). - 13C NMR (62.9 MHz, [D6] DMSO): δ = 126.79 (Cquat), 129.36 (+), 130.57 (+), 139.1 (Cquat), 165.1 (NCN).

References

[1] European Journal of Organic Chemistry, 2006, # 12, p. 2753 - 2765
[2] Patent: WO2006/94604, 2006, A1. Location in patent: Page/Page column 62; 63; 72; 73
[3] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 17, p. 5235 - 5246
[4] Journal of the American Chemical Society, 1985, vol. 107, # 9, p. 2743 - 2748
[5] Patent: US6218538, 2001, B1

4-Chlorobenzene-1-carboximidamide hydrochloride Preparation Products And Raw materials

Raw materials

4-Chlorobenzonitrile Sodium Ammonium chloride Methanol

Preparation Products

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4-Chlorobenzene-1-carboximidamide hydrochloride Suppliers

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View Lastest Price from 4-Chlorobenzene-1-carboximidamide hydrochloride manufacturers

Honest Joy Holdings Limited
Product
4-Chlorobenzene-1-carboximidamide, HCl 14401-51-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99.3%
Supply Ability
100 tons
Release date
2022-01-26
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Chlorobenzene-1-carboximidamide hydrochloride 14401-51-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
4-Chlorobenzene-1-carboximidamide hydrochloride 14401-51-5
Price
US $8.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10MT
Release date
2018-12-17

14401-51-5, 4-Chlorobenzene-1-carboximidamide hydrochlorideRelated Search:

Amitraz Chlorobenzene Benzamidine hydrochloride BENZAMIDINE 1,2,4-Trichlorobenzene Topotecan hydrochloride D-Glucosamine hydrochloride Cefmenoxime hydrochloride Triethylamine hydrochloride Formamidine hydrochloride Pigment Geen 7 Pigment Green 36 2,4-DICHLORO-N'-HYDROXYBENZENECARBOXIMIDAMIDE 2-Chlorobenzene-1-carboximidamide hydrochloride 3-Chlorobenzene-1-carboximidamide hydrochloride IRON(II) 1,2,3,4,8,9,10,11,15,16,17,18,22,23,24,25-HEXADECACHLORO-29 H,31 H-PHTHALOCYANINE 4-CHLORO-BENZAMIDINE 4-Chlorobenzene-1-carboximidamide hydrochloride

  • 4-Chlorobenzamidine hydrochloride ,95%
  • 4-Chlorobenzenecarboximidamide hydrochloride, 4-Chlorobenzimidamide hydrochloride
  • 4-chlorobenzimidamide hydrochloride
  • Benzenecarboximidamide,4-chloro-, hydrochloride (1:1)
  • 4-chlorobenzenecarboximidamidemonohydrochloride
  • 4-chloro-benzenecarboximidamidmonohydrochloride
  • p-chloro-benzamidhydrochloride
  • p-chloro-benzamidinmonohydrochloride
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  • 4-ChlorobenzamidineHydrochloride&gt
  • 4-chlorbenamidine hydrochloride
  • 4-chloro-Benzenecarboximidamide hydrochloride (1:1)
  • 4-Chlorobenzimidamide HCl
  • 14401-51-5
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  • C7H7ClN2HCl
  • pharmacetical