Lexithromycin

Product Name: Lexithromycin
CAS No.: 53066-26-5
Chemical Name: Lexithromycin
Synonyms: Wy 48314;Lexithromycin;Erythromycin A-E-oxime;Azithromycin Impurity 4;erythromycin A methoxime;Azithromycin Impurity 31;Erythromycin A 9-Methoxime;Erythromycin, 9-(O-methyloxime);9-(Methoxyimino)-9-deoxoerythromycin;ErythroMycin A 9-MethoxiMe, Wy 48314
CBNumber: CB41327717
Molecular Formula: C38H70N2O13
Formula Weight: 762.97
MOL File: 53066-26-5.mol

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Lexithromycin Property

Melting point:: >115°C (dec.)
Boiling point:: 824.6±75.0 °C(Predicted)
Density: 1.26±0.1 g/cm3(Predicted)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: Chloroform (Slightly), DMSO (Slightly)
pka: 13.19±0.70(Predicted)
form: Solid
color: White to Off-White
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22002
Product name: Lexithromycin
Purity: ≥98%
Packaging: 5mg
Price: $171
Updated: 2024/03/01

Cayman Chemical

Product number: 22002
Product name: Lexithromycin
Purity: ≥98%
Packaging: 25mg
Price: $760
Updated: 2024/03/01

ChemScene

Product number: CS-0026970
Product name: Lexithromycin
Purity: 98.80%
Packaging: 100mg
Price: $1650
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0011780
Product name: LEXITHROMYCIN
Purity: 95.00%
Packaging: 5MG
Price: $502.99
Updated: 2021/12/16

ChemScene

Product number: CS-0026970
Product name: Lexithromycin
Purity: 98.80%
Packaging: 25mg
Price: $550
Updated: 2021/12/16

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Lexithromycin Chemical Properties,Usage,Production

Description

Lexithromycin is a semisynthetic antibiotic derived from erythromycin . Lexithromycin has improved absorption in vivo over erythromycin due to increased hydrophopicity and pH stability. As with other macrolides, lexithromycin prevents protein synthesis by binding the ribosome at the polypeptide exit tunnel. Formulations containing lexithromycin were tested in clinical trials as treatment for HIV but were discontinued.

Uses

Lexithromycin is an early semi-synthetic erythromycin, prepared by reaction of the 9-keto moiety to methyl oxime. The structural change improves the pH stability profile and hydrophobicity of lexithromycin for better in vivo absorption. This same rationale was used to greater effect with roxithromycin and, as a result, lexithromycin was quickly superseded and has not been not extensively studied. Like all tetracyclines, lexithromycin shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.

Uses

Lexithromycin is a semi-synthetic erythromycin with improved pH stability and hydrophobicity. It is used in compositions and methods for treating viral infections.

Lexithromycin Preparation Products And Raw materials

Raw materials

Preparation Products

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Lexithromycin Suppliers

China 37 United Kingdom 1 United States 7 Global 45

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
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Advantage: 50

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 17981
Advantage: 56

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9911
Advantage: 50

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-58362220 15250997978
Fax: 025-58362220
Email: 1511893459@qq.com
Country: China
ProdList: 7730
Advantage: 55

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12308
Advantage: 58

Lynnchem

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Novachemistry

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Shenzhen SUNGENING Bio-Medical Co., Ltd.

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PI & PI BIOTECH INC.

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Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
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53066-26-5, LexithromycinRelated Search:

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erythromycin A methoxime

9-(Methoxyimino)-9-deoxoerythromycin

9-Deoxo-9-[[methyloxy]imino]erythromycin

ErythroMycin A 9-MethoxiMe, Wy 48314

Erythromycin A-E-oxime

Erythromycin A-E-oxime LEXITHROMYCIN.

Erythromycin A 9-Methoxime

Azithromycin Impurity 4

Azithromycin Impurity 31

Lexithromycin

Wy 48314

Erythromycin, 9-(O-methyloxime)

53066-26-5