Azathramycin

Product Name: Azathramycin
CAS No.: 76801-85-9
Chemical Name: Azathramycin
Synonyms: Azithromycin Amine;DESMETHYL AZITHROMYCIN;Desmethyl;Azaerythromycin A;Azithromycin Impurity P;Azithromycin A;9-DEOXO-9A-AZA-9A-HEMOERYTHROMYCIN;Azathramycin;Azathramycin A;Azaerthromycin A
CBNumber: CB0501390
Molecular Formula: C37H70N2O12
Formula Weight: 734.96
MOL File: 76801-85-9.mol

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Azathramycin Property

Melting point:: 126-136°C
Boiling point:: 815.2±65.0 °C(Predicted)
Density: 1.18
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka: 13.29±0.70(Predicted)
form: Solid
color: White to Off-White
Stability:: Hygroscopic
InChI: InChI=1/C37H70N2O12/c1-14-26-37(10,45)30(41)23(6)38-18-19(2)16-35(8,44)32(51-34-28(40)25(39(11)12)15-20(3)47-34)21(4)29(22(5)33(43)49-26)50-27-17-36(9,46-13)31(42)24(7)48-27/h19-32,34,38,40-42,44-45H,14-18H2,1-13H3/t19-,20-,21+,22-,23-,24+,25+,26-,27+,28-,29+,30-,31+,32-,34+,35-,36-,37-/s3
InChIKey: HRKNNHYKWGYTEN-HOQMJRDDSA-N
SMILES: [C@H]1(O[C@H](C)C[C@H](N(C)C)[C@H]1O)O[C@@]1([H])[C@](C)(O)C[C@@H](C)CN[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@H](C)[C@@]([H])(O[C@@H]2O[C@@H](C)[C@H](O)[C@](C)(OC)C2)[C@@H]1C |&1:0,2,5,9,12,14,18,22,24,26,29,35,37,40,42,44,46,51,r|
LogP: 3.11
CAS DataBase Reference: 76801-85-9

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Safety

HS Code: 2934990002

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR2780
Product name: Azaerythromycin A
Purity: Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 200?mg
Packaging: 200MG
Price: $494.95
Updated: 2025/07/31

Sigma-Aldrich

Product number: 1045600
Product name: Azaerythromycin A
Packaging: 100mg
Price: $1360
Updated: 2025/07/31

TRC

Product number: D231500
Product name: 9-Deoxo-9a-aza-9a-homoErythromycinA(DesmethylAzithromycin)
Packaging: 100mg
Price: $125
Updated: 2021/12/16

Usbiological

Product number: 257268
Product name: 9-Deoxo-9a-aza-9a-homo erythromycin A
Packaging: 25g
Price: $326
Updated: 2021/12/16

TRC

Product number: D231500
Product name: 9-Deoxo-9a-aza-9a-homoErythromycinA(DesmethylAzithromycin)
Packaging: 1g
Price: $425
Updated: 2021/12/16

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Azathramycin Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

9-Deoxo-9a-aza-9a-homo Erythromycin A (Azithromycin EP Impurity A) is a novel intermediate of Azithromycin that acts as antibiotic.

Synthesis

342371-84-0

76801-85-9

Example-2; [93] [94] Preparation of 9-deoxy-9a-azo-9a-homoerythromycin A; Acetic acid was added dropwise to a methanolic (700 mL) suspension of 6,9-imino ether (II) (70.0 g), and the pH was adjusted to 5-6. Subsequently, an aqueous solution of PtO2 (7.0 g) was added to the above mixture and the reaction was carried out under a hydrogen pressure of 8-9 kg/cm2 and a temperature of 40-45°C for 4-5 hours for the hydrogenation reduction reaction. After completion of the reaction, the reaction mixture was filtered through Hyflo Super Cel and the filter cake was washed with methanol. The filtrates were combined and the methanol was removed by distillation under reduced pressure. To the residue, deionized water (700 mL) was added and the pH was adjusted to 11-12 with aqueous sodium hydroxide.The precipitated solid was filtered, drained, and dried in an oven to afford 9-deoxy-9a-azo-9a- homoerythromycin A(III) (55.0 g) in 85% yield.

References

[1] Patent: WO2009/156938, 2009, A2. Location in patent: Page/Page column 8
[2] Patent: CN106632543, 2017, A. Location in patent: Paragraph 0003; 0025-0026
[3] Organic and Biomolecular Chemistry, 2008, vol. 6, # 22, p. 4120 - 4124
[4] Patent: CN106478541, 2017, A. Location in patent: Paragraph 0022; 0047

Azathramycin Preparation Products And Raw materials

Raw materials

Preparation Products

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Azathramycin Suppliers

Canada 1 China 227 India 26 United Kingdom 3 United States 15 Global 272

UHN Shanghai Research & Development Co., Ltd.

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Hubei Weideli Chemical Reagent Co.，Ltd.

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J & K SCIENTIFIC LTD.

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Beijing Ouhe Technology Co., Ltd

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Nanjing Chemlin Chemical Co., Ltd

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Chemsky（shanghai）International Co.,Ltd.

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Sinopharm Chemical Reagent Co,Ltd.

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Hangzhou Yuhao Chemical Technology Co., Ltd

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T&W GROUP

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S.Z. PhyStandard Bio-Tech. Co., Ltd.

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ProdList: 5158
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View Lastest Price from Azathramycin manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd

Product: Azathramycin 76801-85-9
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: Customise
Release date: 2025-11-20

RongNa Biotechnology Co.,Ltd

Product: Azathramycin 76801-85-9
Price: US $1.00/g
Min. Order: 1g
Purity: 0.99
Supply Ability: 20 tons
Release date: 2025-06-02

Shaanxi Dideu New Materials Co. Ltd

Product: Azathramycin 76801-85-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-05-07

76801-85-9, AzathramycinRelated Search:

AZITHROMYCIN IMPURITY B Lexithromycin Azithromycin aspartate water-soluble azithromycin 70% Tulathromycin A Azithromycin dihydrate Erythromycin AZITHROMYCIN IMPURITY A THIOXANTHENE Azithromycin Monohydrate ERYTHROMYCIN LACTOBIONATE (200 MG) 2-Desethyl-2-propylazithromycin DesosaMinylazithroMycin 2-(2H-Benzotriazol-2-yl)-p-cresol beta-D-Desosamine 3'-N,N-Di(desMethyl)-3'-N-forMyl AzithroMycin 9a-aza-9a-homo Erythromycin A AZITHROMYCIN-D3

Azithromycin EP Impurity A/(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one

Azithromycin Impurity P

Azathramycin (Azaerythromycin A

Azithromycin EP Impurity A (Azathramycin) (Desmethyl Azithromycin)

AZAERYTHROMYCIN A;DESMETHYL AZITHROMYCIN

Azithromycin Impurity 1（Azithromycin EP Impurity A）

DD-Azaerythromycin A

Desmethylazythromicin

9-Deoxo-9a-aza-9a-homo Erythromycin A Desmethyl Azithromycin

AzithroMycin InterMediates

9-DEOXO-9A-AZA-9A-HEMOERYTHROMYCIN

10-Dihydro-10-deoxo-11-azaethrythroMycin A

1-Oxa-6-azacyclopentadecan-15-one,13-[(2,6-dideoxy-3-C-Methyl-3-O-Methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexaMethyl-11-[[3,4,6-trideoxy-3-(diMethylaMino)-b-D-xylo-hexopyranosyl]oxy]-,(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R

Azathramycin (Desmethyl Azithromycin)

Azaerthromycin A

Azithromycin EP Impurity A

9-Deoxo-9A-Aza-9A-Hom Oerythromycin A (Azithromycin Amine)

Azithromycin mpurity A

6-DeMethylazithroMycin (AzaerythroMycin A)

Azithromycin A

Azithromycin Amine

N6-Demethylazithromycin

Azithromycin Impurity U

1-Oxa-6-azacyclopentadecan-15-one

AZAERYTHROMYCIN A (100 MG) (9-DEOXO-9A-AZA-9A-HOMOERYTHROMYCIN A)

9-Deoxo-9a-aza-9a-homo Erythromycin A

Azaerythromycin A

Azathramycin

Desmethyl

10-dihydro-10-deoxo-11-azaerythromycin A

DESMETHYL AZITHROMYCIN

Azithromycin impurity A CRS

6-Demethylazithromycin (Azaerythrom

1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-

AZITHROMYCIN INTEMEDIATES

USP Azaerythromycin A

Azithromycin Imp.A (EP): 6-Demethylazithromycin (Azaerythromycin A)

Azathramycin A

Azithromycin EP Impurity A (N6-Demethylazithromycin/ Desmethylazithromycin/ 9-Deoxo-9a-aza-9a-homo Erythromycin A/ Azaerythromycin A/ Azathramycin)

Azithromycin Imp-A

9-Deoxo-9a-aza-9a-homo Erythromycin A (Azithromycin EP Impurity A/ N6-Demethylazithromycin/ Desmethylazithromycin/ Azaerythromycin A/ Azathramycin)

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-

Azithromycin EP Impurity AQ: What is Azithromycin EP Impurity A Q: What is the CAS Number of Azithromycin EP Impurity A Q: What is the storage condition of Azithromycin EP Impurity A Q: What are the applications of Azithromycin EP Impurity A

Azaerythromycin (AZAE)

Azaerythromycin A (9-Deoxo-9a-aza-9a-homoerythromycin A) (1045600)

Azaerythromycin A (（Azithromycin Amine)

1-Oxa-6-azacyclopentadecan-15-one,13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-

9-Deoxo-9α-azα-9α-homo Erythromycin A (Desmethyl Azithromycin)

(2R,3S,4R,5R,8R,10R,11R,12S,1(2R,3S,4R,5R,8R,10R,11R,12S, 13S,14R)-11-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6- methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy- 13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro- 2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-1-oxa-6- azacyclopentadecan-15-one

Azithromycin EP Impurity A (Azathramycin)

Azathramycin, 10 mM in DMSO

(2R,3S,4R,5R,8R,10R,11R,12S,1(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy13-(((2R,4R,5S,6S)-5-hyd

Dihydrohomoerythromycin

Dihydroerythromycin

Azithromycin EP Impurity A (6-Demethyl Azithromycin)

Azithramycin Amine