ChemicalBook > CAS DataBase List > GW0742

GW0742

Product Name
GW0742
CAS No.
317318-84-6
Chemical Name
GW0742
Synonyms
GW0742;CS-2560;GW 0742X;GW 610742;GWdelta 0742;Sarms Gw0742;GW0742 sarms;GW0742 / GW0742;GW0742(GW610742);GW0742 USP/EP/BP
CBNumber
CB4138491
Molecular Formula
C21H17F4NO3S2
Formula Weight
471.49
MOL File
317318-84-6.mol
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GW0742 Property

Melting point:
134.5-135.5 °C
Boiling point:
591.5±60.0 °C(Predicted)
Density 
1.46±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: >5 mg/mL
form 
solid
pka
3.17±0.10(Predicted)
color 
white
InChI
InChI=1S/C21H17F4NO3S2/c1-11-7-14(4-6-17(11)29-9-19(27)28)30-10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23,24)25/h3-8H,9-10H2,1-2H3,(H,27,28)
InChIKey
HWVNEWGKWRGSRK-UHFFFAOYSA-N
SMILES
C(O)(=O)COC1=CC=C(SCC2SC(C3=CC=C(C(F)(F)F)C(F)=C3)=NC=2C)C=C1C
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Safety

WGK Germany 
3
HS Code 
38220090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G3295
Product name
GW0742
Purity
≥98% (HPLC)
Packaging
1mg
Price
$233
Updated
2024/03/01
Sigma-Aldrich
Product number
G3295
Product name
GW0742
Purity
≥98% (HPLC)
Packaging
5mg
Price
$798
Updated
2024/03/01
Cayman Chemical
Product number
10006798
Product name
GW 0742
Purity
≥95%
Packaging
5mg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
10006798
Product name
GW 0742
Purity
≥95%
Packaging
10mg
Price
$152
Updated
2024/03/01
Cayman Chemical
Product number
10006798
Product name
GW 0742
Purity
≥95%
Packaging
25mg
Price
$356
Updated
2024/03/01
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GW0742 Chemical Properties,Usage,Production

Description

GW0742 is a PPARδ/β agonist very similar in molecular structure to GW501516 (Cardarine) — with the exception of one atom. It is often mentioned in comparison with Cardarine. This drug is mostly used by athletes to improve their stamina. The fat affecting properties of GW0742 also make it a good promoter of energy in the body. Additionally, this drug helps increase the oxidative abilities of your body muscles.

Chemical Properties

Light Yellow Solid

Uses

GW0742 is a small molecule agonist of the human Peroxisome Proliferator-Activated Recept δ (PPAR δ). It shows an EC50 of 1.1 nM against PPAR δ with 100-fold selectivity over the other human subtypes.

Definition

ChEBI: GW 0742 is a monocarboxylic acid.

Biological Activity

GW 0742 is a potent and highly selective PPARδ agonist. EC50 values are 0.001, 1.1 and 2 μM for transactivation of human PPARδ, -α, and -γ receptors respectively. Neuroprotective in rat cerebellar granule neuronal cultures after brief (12-hour) exposure but exhibits inherent toxicity after prolonged (48-hour) incubation. Increases rate of fatty acid oxidation and protects against ischemia/reperfusion injury in neonatal and adult cardiomyocytes.

storage

Desiccate at +4°C

GW0742 Preparation Products And Raw materials

Raw materials

Preparation Products

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GW0742 Suppliers

SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from GW0742 manufacturers

Dorne Chemical Technology co. LTD
Product
GW0742 317318-84-6
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
100kg
Release date
2024-03-26
hebei hongtan Biotechnology Co., Ltd
Product
GW0742 317318-84-6
Price
US $50.00-400.00/g
Min. Order
10g
Purity
98%
Supply Ability
2000kg
Release date
2024-06-05
Shanghai Longyu Biotechnology Co., Ltd.
Product
GW0742 317318-84-6
Price
US $1.00/g
Min. Order
1g
Purity
99
Supply Ability
20tons
Release date
2024-11-23

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