ChemicalBook > CAS DataBase List > (2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid

(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid

Product Name
(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid
CAS No.
135042-12-5
Chemical Name
(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid
Synonyms
BOC-D-CISHYP-OH;Boc-cis-D-Hyp-OH;cis-Boc-D-Hyp-OH;N-Boc-D-cis-Hyp-OH;N-Boc-cis-D-Hyp-OH;ATTERCOP-CHM AT700573;Boc-cis-4-hydroxy-D-proL;BOC-CIS-4-HYDROXY-D-PROLINE;N-BOC-CIS-6-HYDROXY-D-PROLINE;N-BOC-CIS-4-HYDROXY-D-PROLINE
CBNumber
CB4141253
Molecular Formula
C10H17NO5
Formula Weight
231.25
MOL File
135042-12-5.mol
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(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid Property

Melting point:
146-151 °C
alpha 
+48～+52°(c=0.67,MeOH,24℃)
Boiling point:
390.9±42.0 °C(Predicted)
Density 
1.312
storage temp. 
2-8°C
pka
3.80±0.40(Predicted)
form 
powder to crystal
color 
White to Light yellow
optical activity
[α]22/D +50.0°, c = 1 in methanol
InChIKey
BENKAPCDIOILGV-RNFRBKRXSA-N
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Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
706574
Product name
N-Boc-cis-4-hydroxy-D-proline
Purity
97%
Packaging
1g
Price
$74.5
Updated
2023/06/20
TCI Chemical
Product number
B5886
Product name
cis-N-(tert-Butoxycarbonyl)-4-hydroxy-D-proline
Packaging
1G
Price
$34
Updated
2024/03/01
TCI Chemical
Product number
B5886
Product name
cis-N-(tert-Butoxycarbonyl)-4-hydroxy-D-proline
Packaging
5G
Price
$95
Updated
2024/03/01
TRC
Product number
H945705
Product name
(2R,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylicAcid1-(1,1-Dimethylethyl)Ester
Packaging
250mg
Price
$50
Updated
2021/12/16
TRC
Product number
H945705
Product name
(2R,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylicAcid1-(1,1-Dimethylethyl)Ester
Packaging
2.5g
Price
$75
Updated
2021/12/16
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(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

N-Boc-cis-4-hydroxy-D-proline can be used:

  • As a starting material in the synthesis of DNA mimicking pyrrolidine peptide nucleic acid (PNA) analog.
  • In the synthesis of biologically important macrocyclic dilactones.
  • As an intermediate in the synthesis of histamine H3?receptor antagonists.

(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid Suppliers

Americas 1 Canada 1 China 179 Europe 1 France 1 Germany 1 India 3 Japan 3 United Kingdom 2 United States 22 Global 214
Tebu-bio
Tel
--
Fax
--
Email
gilles.cestelli@tebu-bio.com
Country
France
ProdList
251
Advantage
75
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View Lastest Price from (2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid manufacturers

Honest Joy Holdings Limited
Product
N-Boc-cis-4-hydroxy-D-proline 135042-12-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99.5%
Supply Ability
100 tons
Release date
2022-01-25
Zhuozhou Wenxi import and Export Co., Ltd
Product
(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid 135042-12-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
(2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid 135042-12-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

135042-12-5, (2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acidRelated Search:

tert-Butyl peroxyacetate OXALIC ACID Salicylic acid L-PROLINE-(4-3H(N)) BOC-L-Proline 2,3,4-Trihydroxybenzoic acid trans-4-Hydroxy-D-proline tert-Butanol Ethyl 2-(Chlorosulfonyl)acetate 2'-Hydroxy-3-phenylpropiophenone Folic acid Citric acid cis-4-Hydroxy-L-proline BUTYL OLEATE Buprofezin Butyl acetate Cyhalofop-butyl 4-Hydroxybenzoic acid

  • (2R,4R)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID
  • BOC-(2R,4R)-(+)-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID
  • BOC-CIS-4-HYDROXY-D-PROLINE
  • BOC-D-CISHYP-OH
  • N-T-BOC-CIS-4-HYDROXY-D-PROLINE
  • N-BOC-CIS-4-HYDROXY-D-PROLINE
  • N-ALPHA-BUTOXYCARBONYL-CIS-4-HYDROXY-D-PROLINE
  • N-BOC-CIS-6-HYDROXY-D-PROLINE
  • (2r,4r)-n-boc-4-hydroxypyrrolidine-2-carboxylic acid
  • (2R,4R)-N-BOC-4-HYDROXY-D-PROLINE
  • (2R,4R)-1-tert-Butoxycarbonyl-4-hydroxypyrrolidine-2-carboxylic acid
  • (2R,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
  • (2R,4R)-N-Boc-4-hydroxy-2-pyrrolidinecarboxylic acid
  • ATTERCOP-CHM AT700573
  • (4R)-1-(tert-Butoxycarbonyl)-4-hydroxy-D-proline
  • 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-diMethylethyl) ester, (2R-cis)-
  • Boc-cis-D-Hyp-OH
  • cis-Boc-D-Hyp-OH
  • N-Boc-D-cis-Hyp-OH
  • 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-diMethylethyl) ester, (2R,4R)-
  • (Tert-Butoxy)Carbonyl cis-D-Hyp-OH
  • cis-N-Boc-4-hydroxy-D-proline
  • N-Boc-cis-4-hydroxy-D-proline 95+%
  • (2R,4R)N-Boc-trans-4-hydroxy-D-proline
  • (2R,4R)-N-Boc-cis-4-hydroxy-D-proline
  • N-Boc-cis-D-Hyp-OH
  • cis-N-(tert-Butoxycarbonyl)-4-hydroxy-D-proline
  • Boc-cis-4-hydroxy-D-proL
  • (2R,4R)-N-Boc-4-hydroxypyrrolidine-2-carboxylic acid USP/EP/BP
  • N-α-(t-Butoxycarbonyl)-cis-4-hydroxy-D-proline
  • 1-(1,1-Dimethylethyl) (2R,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate
  • 135042-12-5
  • C10H17NO7