2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid

Product Name: 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid
CAS No.: 52916-16-2
Chemical Name: 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid
Synonyms: 2,2-dimethyloxane-4-carboxylic acid;2,2-dimethyl-4-tetrahydropyrancarboxylic acid;2,2-dimethyloxane-4-carboxylic acid - [D86899];2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid;tetrahydro-2,2-dimethyl-2H-pyran-4-carboxylic acid;2H-Pyran-4-carboxylic acid, tetrahydro-2,2-dimethyl-;2,2-dimethyltetrahydro-2H-pyran-4-carboxylic acid(SALTDATA: FREE)
CBNumber: CB41482128
Molecular Formula: C8H14O3
Formula Weight: 158.2
MOL File: 52916-16-2.mol

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2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid Property

Melting point:: 102 °C
Boiling point:: 261.8±33.0 °C(Predicted)
Density: 1.067±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 4.45±0.40(Predicted)
Appearance: Off-white to light yellow Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: D457838
Product name: 2,2-dimethyltetrahydro-2H-pyran-4-carboxylicacid
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD136168
Product name: 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid
Packaging: 100mg
Price: $72
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD136168
Product name: 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid
Packaging: 250mg
Price: $145
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD136168
Product name: 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid
Packaging: 500mg
Price: $250
Updated: 2021/12/16

Matrix Scientific

Product number: 159697
Product name: 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid
Packaging: 0.500g
Price: $400
Updated: 2021/12/16

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2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid Chemical Properties,Usage,Production

Synthesis

60549-63-5

52916-16-2

The reaction was carried out overnight at reflux in 2N KOH aqueous solution using 2,2-dimethyltetrahydro-2H-pyran-4-carbonitrile (900 mg, 6.47 mmol) as raw material. After completion of the reaction, the reaction mixture was diluted with water and extracted with ethyl acetate and the organic phase was discarded. The aqueous phase was acidified to pH < 7 with 2N HCl solution and subsequently extracted twice with ethyl acetate. The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated in vacuum to give the crude product 2,2-dimethyltetrahydro-2H-pyran-4-carboxylic acid (889 mg, 5.62 mmol, 87% yield). The product was characterized by 1H-NMR (400 MHz, DMSO-d6): δ[ppm] 1.13 (s, 3H), 1.14 (s, 3H), 1.26-1.45 (m, 2H), 1.65-1.73 (m, 2H), 2.59 (tt, 1H), 3.54 (td, 1H), 3.60 (ddd, 1H), 12.20 (s, 1H).

References

[1] Patent: WO2016/198374, 2016, A1. Location in patent: Page/Page column 131-132

2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid Suppliers

China 62 France 1 India 1 Russia 2 United Kingdom 1 United States 6 Global 73

Accela ChemBio Inc.

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View Lastest Price from 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid 52916-16-2
Price: US $1.60-6.60/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-19

Career Henan Chemical Co

Product: 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid 52916-16-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1kg-1000kg
Release date: 2020-01-03

52916-16-2, 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acidRelated Search:

Centchroman N,N-Dimethylformamide Dimethyl sulfoxide Poly(dimethylsiloxane) Tetrahydro-4H-pyran-4-one Tetrahydropyran-4-carbaldehyde Tetrahydro-2H-pyran-4-carboxylic acid CARBOXYLIC ACID 2,2-DIMETHYL-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID METHYL ESTER 2,2-DIMETHYL-TETRAHYDRO-PYRAN-4-CARBALDEHYDE 2,2-DIMETHYL-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID ETHYL ESTER 2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid

tetrahydro-2,2-dimethyl-2H-pyran-4-carboxylic acid

2,2-Dimethyltetrahydro-2H-pyran-4-carboxylic acid

2,2-dimethyltetrahydro-2H-pyran-4-carboxylic acid(SALTDATA: FREE)

2,2-dimethyl-4-tetrahydropyrancarboxylic acid

2,2-dimethyloxane-4-carboxylic acid

2H-Pyran-4-carboxylic acid, tetrahydro-2,2-dimethyl-

2,2-dimethyloxane-4-carboxylic acid - [D86899]

52916-16-2