4-FLUORO-2-METHOXYANILINE
Physical Form- Product Name
- 4-FLUORO-2-METHOXYANILINE
- CAS No.
- 450-91-9
- Chemical Name
- 4-FLUORO-2-METHOXYANILINE
- Synonyms
- 4-Fluoro-2-MethoxybenzenaMine;4-Fluoro-2-methoxy-phenylamine;4-Fluoro-o-anisidine;o-Anisidine, 4-fluoro-;2-Amino-5-fluoroanisole;4-Fluro-2-methoxyaniline;4-FLUORO-2-METHOXYANILINE;2-Methoxy-4-fluoroaniline;4-fluoro-2-o-methoxyaniline;4-Fluoro-2-methoxyaniline 97%
- CBNumber
- CB41494695
- Molecular Formula
- C7H8FNO
- Formula Weight
- 141.14
- MOL File
- 450-91-9.mol
4-FLUORO-2-METHOXYANILINE Property
- Boiling point:
- 215℃ (756 Torr)
- Density
- 1.176±0.06 g/cm3 (20 ºC 760 Torr)
- refractive index
- 1.5400 to 1.5440
- Flash point:
- 79.5±21.8℃
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- Solid
- pka
- 4.60±0.10(Predicted)
- color
- Colorless to Brown
- InChI
- InChI=1S/C7H8FNO/c1-10-7-4-5(8)2-3-6(7)9/h2-4H,9H2,1H3
- InChIKey
- BNRRMRUVYDETQC-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=C(F)C=C1OC
Safety
- RIDADR
- 2810
- HazardClass
- 6.1
- PackingGroup
- Ⅲ
- HS Code
- 2921420090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- F1003
- Product name
- 4-Fluoro-2-methoxyaniline
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $95
- Updated
- 2025/07/31
- Product number
- F1003
- Product name
- 4-Fluoro-2-methoxyaniline
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $282
- Updated
- 2025/07/31
- Product number
- F593190
- Product name
- 4-Fluoro-2-methoxyaniline
- Packaging
- 25g
- Price
- $1185
- Updated
- 2021/12/16
- Product number
- HCH0050966
- Product name
- 4-FLUORO-2-METHOXYANILINE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1421.65
- Updated
- 2021/12/16
- Product number
- HCH0050966
- Product name
- 4-FLUORO-2-METHOXYANILINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $808.89
- Updated
- 2021/12/16
4-FLUORO-2-METHOXYANILINE Chemical Properties,Usage,Production
Physical Form
Yellow to Orange to Brown Solid or liquid
Application
4-Fluoro-2-methoxyaniline is a useful synthetic intermediate. It is used to prepare ortho-substituted phenylureas as 5-Hydroxytryptamine (5-HT3) receptor antagonists. It is also used to synthesize hydroxamic acids and their prodrugs as inhibitors for Botulinum neurotoxin A light chain.
Synthesis
Using 4-fluoro-2-o-methoxynitrobenzene as the starting material, the target compound 4-fluoro-2-methoxyaniline was prepared by hydrogenation reduction reaction.
References
[1] Patent: US6352993, 2002, B1. Location in patent: Page column 30
[2] Patent: CN106366072, 2017, A. Location in patent: Paragraph 0062; 0063; 0064; 0090; 0091; 0092
[3] Patent: CN106366022, 2017, A. Location in patent: Paragraph 0051; 0052; 0056
[4] Patent: US2011/130415, 2011, A1. Location in patent: Page/Page column 102
[5] Patent: WO2018/207120, 2018, A1. Location in patent: Page/Page column 11; 12
4-FLUORO-2-METHOXYANILINE Preparation Products And Raw materials
Raw materials
Preparation Products
4-FLUORO-2-METHOXYANILINE Suppliers
- Tel
- 19512299079,021-31371965,15000810423 19512299079
- 2260325220@qq.com
- Country
- China
- ProdList
- 59
- Advantage
- 58
- Tel
- 010-59484199 18611897322
- sales@eternalchem.com
- Country
- China
- ProdList
- 4383
- Advantage
- 60
- Tel
- 15858180887
- 66878391@qq.com
- Country
- China
- ProdList
- 46
- Advantage
- 58
- Tel
- 18367323072
- 2125193158@qq.com
- Country
- China
- ProdList
- 367
- Advantage
- 58
- Tel
- 0534-2152677 18660163165
- sale@inyelchem.com
- Country
- China
- ProdList
- 264
- Advantage
- 58
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 0311-89250318 031166536426
- Fax
- 4000311741
- master@sjzsdyn.com
- Country
- China
- ProdList
- 2809
- Advantage
- 65
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
View Lastest Price from 4-FLUORO-2-METHOXYANILINE manufacturers
- Product
- 4-FLUORO-2-METHOXYANILINE 450-91-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-30
- Product
- 4-FLUORO-2-METHOXYANILINE 450-91-9
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-03-05
- Product
- 4-Fluoro-2-Methoxyaniline 450-91-9
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-08-21