ChemicalBook > CAS DataBase List > 4-FLUORO-2-METHOXYANILINE

4-FLUORO-2-METHOXYANILINE

Physical Form

Product Name: 4-FLUORO-2-METHOXYANILINE
CAS No.: 450-91-9
Chemical Name: 4-FLUORO-2-METHOXYANILINE
Synonyms: 4-Fluoro-2-MethoxybenzenaMine;4-Fluoro-2-methoxy-phenylamine;4-Fluoro-o-anisidine;o-Anisidine, 4-fluoro-;2-Amino-5-fluoroanisole;4-Fluro-2-methoxyaniline;4-FLUORO-2-METHOXYANILINE;2-Methoxy-4-fluoroaniline;4-fluoro-2-o-methoxyaniline;4-Fluoro-2-methoxyaniline 97%
CBNumber: CB41494695
Molecular Formula: C7H8FNO
Formula Weight: 141.14
MOL File: 450-91-9.mol

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4-FLUORO-2-METHOXYANILINE Property

Boiling point:: 215℃ (756 Torr)
Density: 1.176±0.06 g/cm3 (20 ºC 760 Torr)
refractive index: 1.5400 to 1.5440
Flash point:: 79.5±21.8℃
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: Solid
pka: 4.60±0.10(Predicted)
color: Colorless to Brown
InChI: InChI=1S/C7H8FNO/c1-10-7-4-5(8)2-3-6(7)9/h2-4H,9H2,1H3
InChIKey: BNRRMRUVYDETQC-UHFFFAOYSA-N
SMILES: C1(N)=CC=C(F)C=C1OC

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Safety

RIDADR: 2810
HazardClass: 6.1
PackingGroup: Ⅲ
HS Code: 2921420090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: F1003
Product name: 4-Fluoro-2-methoxyaniline
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $95
Updated: 2025/07/31

TCI Chemical

Product number: F1003
Product name: 4-Fluoro-2-methoxyaniline
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $282
Updated: 2025/07/31

TRC

Product number: F593190
Product name: 4-Fluoro-2-methoxyaniline
Packaging: 25g
Price: $1185
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0050966
Product name: 4-FLUORO-2-METHOXYANILINE
Purity: 95.00%
Packaging: 5G
Price: $1421.65
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0050966
Product name: 4-FLUORO-2-METHOXYANILINE
Purity: 95.00%
Packaging: 1G
Price: $808.89
Updated: 2021/12/16

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4-FLUORO-2-METHOXYANILINE Chemical Properties,Usage,Production

Physical Form

Yellow to Orange to Brown Solid or liquid

Application

4-Fluoro-2-methoxyaniline is a useful synthetic intermediate. It is used to prepare ortho-substituted phenylureas as 5-Hydroxytryptamine (5-HT3) receptor antagonists. It is also used to synthesize hydroxamic acids and their prodrugs as inhibitors for Botulinum neurotoxin A light chain.

Synthesis

Using 4-fluoro-2-o-methoxynitrobenzene as the starting material, the target compound 4-fluoro-2-methoxyaniline was prepared by hydrogenation reduction reaction.

References

[1] Patent: US6352993, 2002, B1. Location in patent: Page column 30
[2] Patent: CN106366072, 2017, A. Location in patent: Paragraph 0062; 0063; 0064; 0090; 0091; 0092
[3] Patent: CN106366022, 2017, A. Location in patent: Paragraph 0051; 0052; 0056
[4] Patent: US2011/130415, 2011, A1. Location in patent: Page/Page column 102
[5] Patent: WO2018/207120, 2018, A1. Location in patent: Page/Page column 11; 12

4-FLUORO-2-METHOXYANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-FLUORO-2-METHOXYANILINE Suppliers

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View Lastest Price from 4-FLUORO-2-METHOXYANILINE manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 4-FLUORO-2-METHOXYANILINE 450-91-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-30

Shaanxi Dideu New Materials Co. Ltd

Product: 4-FLUORO-2-METHOXYANILINE 450-91-9
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-05

Hebei Chuanghai Biotechnology Co,.LTD

Product: 4-Fluoro-2-Methoxyaniline 450-91-9
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-21

450-91-9, 4-FLUORO-2-METHOXYANILINERelated Search:

4-FLUORO-2-METHOXYANILINE 2-Acetonyloxy-3,4-difluoro nitrobenzene Levofloxacin Levofloxacin carboxylic acid Ipodate Sodium Marbofloxacin 5-Fluoro-2-nitroanisole o-Anisidine METHYL 2-(5-FLUORO-2-NITROPHENOXY)ACETATE R-(+)-OFLOXACIN 5-FLUORO-2-NITROPHENYL 4-(CHLOROMETHYL)BENZOATE 5-FLUORO-2-NITROPHENYL 3-METHYLBENZOATE 5-FLUORO-2-NITROPHENYL 2-FLUOROBENZOATE 5-FLUORO-2-NITROPHENYL 4-NITROBENZOATE 5-FLUORO-2-NITROPHENYL 2,6-DIFLUOROBENZOATE 5,5I DIFLUORO BAPTA(K+ SALT) 5-FLUORO-2-NITROPHENYL 2-CHLOROBENZOATE 5-FLUORO-2-NITROPHENYL 2-(2-METHOXYPHENYL)-5-OXOTETRAHYDROFURAN-3-CARBOXYLATE

2-Methoxy-4-fluoroaniline

4-FLUORO-2-METHOXYANILINE

4-Fluoro-2-MethoxybenzenaMine

o-Anisidine, 4-fluoro-

4-Fluoro-2-methoxy-phenylamine

4-Fluoro-o-anisidine, 2-Amino-5-fluoroanisole

2-AMino-5-fluoroanisole[4-Fluoro-2-Methoxyaniline]

2-Amino-5-fluoroanisole

4-Fluoro-2-methoxyaniline 97%

Benzenamine, 4-fluoro-2-methoxy-

4-Fluoro-2-methoxyaniline,95%

4-Fluoro-o-anisidine

4-Fluro-2-methoxyaniline

4-fluoro-2-o-methoxyaniline

450-91-9

450-19-9

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