6-Bromo-2-chloroquinazoline
- Product Name
- 6-Bromo-2-chloroquinazoline
- CAS No.
- 882672-05-1
- Chemical Name
- 6-Bromo-2-chloroquinazoline
- Synonyms
- 6-Bromo-2-chloroquizoline;6-bromo-2-chloroquinazoline;6-BroMo-2-chloroquinazoli...;Quinazoline, 6-bromo-2-chloro-;6-Bromo-2-chloroquinazoline 97%
- CBNumber
- CB41515819
- Molecular Formula
- C8H4BrClN2
- Formula Weight
- 243.49
- MOL File
- 882672-05-1.mol
6-Bromo-2-chloroquinazoline Property
- Boiling point:
- 309.7±24.0 °C(Predicted)
- Density
- 1.762
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- solid
- pka
- -0.54±0.30(Predicted)
- Appearance
- Light yellow to yellow Solid
- InChI
- InChI=1S/C8H4BrClN2/c9-6-1-2-7-5(3-6)4-11-8(10)12-7/h1-4H
- InChIKey
- NYQBZJFZEZEXFP-UHFFFAOYSA-N
- SMILES
- N1=C2C(C=C(Br)C=C2)=CN=C1Cl
Safety
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B684718
- Product name
- 6-Bromo-2-chloroquinazoline
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FB42442
- Product name
- 6-Bromo-2-chloroquinazoline
- Packaging
- 1g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 072441
- Product name
- 6-Bromo-2-chloroquinazoline
- Purity
- 95+%
- Packaging
- 1g
- Price
- $98
- Updated
- 2021/12/16
- Product number
- FB42442
- Product name
- 6-Bromo-2-chloroquinazoline
- Packaging
- 2g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FB42442
- Product name
- 6-Bromo-2-chloroquinazoline
- Packaging
- 5G
- Price
- $150
- Updated
- 2021/12/16
6-Bromo-2-chloroquinazoline Chemical Properties,Usage,Production
Synthesis
79885-37-3
882672-05-1
Step 4: Synthesis of 6-bromo-2-chloroquinazoline. 6-Bromo-2(1H)-quinazolinone (6.0 g, 26.7 mmol) was dissolved in phosphorus oxychloride (POCl3, 80 mL) and the reaction was carried out by refluxing at 110 °C for 5 hours. The reaction progress was monitored by liquid chromatography-mass spectrometry (LCMS) to confirm the completion of the reaction. At the end of the reaction, most of the phosphorous trichloride was evaporated under reduced pressure and the residue was added slowly dropwise to ice water (500 mL). The precipitated yellow solid product was collected by filtration to afford 6-bromo-2-chloroquinazoline (3.5 g, 54% yield). Mass spectrometry (electrospray positive ion mode, ES+) analysis resulted in a theoretical molecular weight of 242 for C8H4BrClN2 and a measured value of 243,245 [M+H]+.
References
[1] Patent: US2015/119405, 2015, A1. Location in patent: Paragraph 0446; 0455; 0456
[2] Patent: WO2014/11900, 2014, A2. Location in patent: Page/Page column 37; 38
[3] Patent: US2015/197519, 2015, A1. Location in patent: Paragraph 0131; 0132
[4] Patent: US9695165, 2017, B2. Location in patent: Page/Page column 38; 39
6-Bromo-2-chloroquinazoline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-Bromo-2-chloroquinazoline manufacturers
- Product
- 6-Bromo-2-chloroquinazoline 882672-05-1
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-06-28
- Product
- 6-Bromo-2-chloroquinazoline 882672-05-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%Min
- Supply Ability
- 1000kg
- Release date
- 2023-03-14
- Product
- 6-Bromo-2-chloroquinazoline 882672-05-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11