12(S)-HPETE

Product Name: 12(S)-HPETE
CAS No.: 71774-10-2
Chemical Name: 12(S)-HPETE
Synonyms: 12(S)-HPETE;12(S)HpETE,12(S) HpETE;ZIOZYRSDNLNNNJ-LQWMCKPYSA-N;12(S)-HpETE Lipid Maps MS Standard;12(S)-Hydroperoxy-eicosatetraenoic acid;(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoic acid;12S-HYDROPEROXY-5Z,8Z,10E,14Z-EICOSATETRAENOIC ACID;12(S)-HYDROPEROXYEICOSA-5Z,8Z,10E,14Z-TETRAENOIC ACID;(5Z,8Z,10E,12S,14Z)-12-Hydroperoxyicosa-5,8,10,14-tetraenoic acid;(5Z,8Z,10E,12S,14Z)-12-Hydroperoxy-5,8,10,14-icosatetraenoic acid
CBNumber: CB4154161
Molecular Formula: C20H32O4
Formula Weight: 336.47
MOL File: 71774-10-2.mol

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12(S)-HPETE Property

Boiling point:: 518.0±50.0 °C(Predicted)
Density: 1.013±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
form: Liquid.
pka: 4.75±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 44570
Product name: 12(S)-HpETE
Purity: ≥98%
Packaging: 25μg
Price: $131
Updated: 2024/03/01

Cayman Chemical

Product number: 44570
Product name: 12(S)-HpETE
Purity: ≥98%
Packaging: 50μg
Price: $246
Updated: 2024/03/01

Cayman Chemical

Product number: 44570
Product name: 12(S)-HpETE
Purity: ≥98%
Packaging: 100μg
Price: $466
Updated: 2024/03/01

Cayman Chemical

Product number: 44570
Product name: 12(S)-HpETE
Purity: ≥98%
Packaging: 250μg
Price: $1030
Updated: 2024/03/01

TRC

Product number: H456410
Product name: 12(S)-HPETE
Packaging: 50μg
Price: $225
Updated: 2021/12/16

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12(S)-HPETE Chemical Properties,Usage,Production

Description

12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid. It activates human blood leukocyte 5-LO, resulting in the synthesis of 5(S)-HETE, leukotriene B₄ (LTB₄), and 5(S),12(S)-DiHETE. Rat lung metabolizes 12(S)-HpETE to 8,11,12- and 10,11,12-trihydroxyeicostrienoic acids. 12(S)-HpETE is the mediator of many biological functions, including induction of c-fos and c-jun, activation of AP-1, and endothelium-dependent vasoconstriction. It mediates the inhibitory synaptic response to FMRF-amide in Aplysia sensory neurons and inhibits Ca²⁺/calmodulin-dependent protein kinase II from rat brain cortex.

Uses

12(S)-HPETE is a fatty acid and an activator of human blood leukocyte 5-LO.

Definition

ChEBI: 12(S)-HPETE is the (S)-enantiomer of 12-HPETE. It has a role as a mouse metabolite. It is functionally related to an icosa-5,8,10,14-tetraenoic acid. It is a conjugate acid of a 12(S)-HPETE(1-). It is an enantiomer of a 12(R)-HPETE.

12(S)-HPETE Preparation Products And Raw materials

Raw materials

Preparation Products

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12(S)-HPETE Suppliers

China 23 Switzerland 1 United Kingdom 1 United States 3 Global 28

Yichang Zhongyitai Trading Co., Ltd.

Tel: 0717-6449896 13886658719
Fax: 0717-6558598
Email: root@zhongyitai.com
Country: China
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Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
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Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6870
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
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MedBioPharmaceutical Technology Inc

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Email: order@med-bio.cn
Country: China
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Shanghai Universal Biotech Co.,Ltd

Tel: 18768175414
Email: gaojun@univ-bio.com
Country: China
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amyjetsci

Tel: 027-59626688 18771149750
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TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
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Shanghai Yiyan Biotechnology Co. , Ltd.

Tel: 021-69985186 13611928337
Email: 3427709316@qq.com
Country: China
ProdList: 7984
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71774-10-2, 12(S)-HPETERelated Search:

12(S)-HPETE LIPID MAPS 12(S)-HPETE [1-14C] 12(R)-HPETE (+/-)12-HPETE 12(S)-HPETE (+/-)12-HETE 12(S)-HETE 1,5-HEPTADIEN-4-OL 1.3.7-OCTATRIENE

12S-HYDROPEROXY-5Z,8Z,10E,14Z-EICOSATETRAENOIC ACID

12(S)-HYDROPEROXYEICOSA-5Z,8Z,10E,14Z-TETRAENOIC ACID

12(S)-HPETE

(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoic acid

(5Z,8Z,10E,12S,14Z)-12-Hydroperoxy-5,8,10,14-icosatetraenoic acid

(5Z,8Z,10E,12S,14Z)-12-Hydroperoxyicosa-5,8,10,14-tetraenoic acid

12(S)-Hydroperoxy-eicosatetraenoic acid

(5Z,8Z,10Z,12S,14Z)-12-Hydroperoxy-5,8,10,14-icosatetraenoic acid

12(S)-HpETE Lipid Maps MS Standard

ZIOZYRSDNLNNNJ-LQWMCKPYSA-N

12(S)HpETE,12(S) HpETE

5,8,10,14-Eicosatetraenoic acid, 12-hydroperoxy-, (5Z,8Z,10E,12S,14Z)-

71774-10-2