ChemicalBook > CAS DataBase List > H-GLU(OBZL)-OTBU HCL

H-GLU(OBZL)-OTBU HCL

Product Name
H-GLU(OBZL)-OTBU HCL
CAS No.
105590-97-4
Chemical Name
H-GLU(OBZL)-OTBU HCL
Synonyms
H-Glu(OBzl)-OtBu;Glu(Obzl)OtBu.HCl;H-GLU(OBZL-OTBU HC;H-GLU(OBZL)-OTBU HCL;L-Glu(OBzl)-OtBu·HCl;H-L-GLU(BZL)-OTBU HCL;H-L-GLU(OBZL)-OTBU HCL;GLUTAMIC ACID(OBZL)-OTBU HCL;H-Glu(Obzl)-Otbu hydrochloride;H-GLU(OBZL)-OTBU HCL USP/EP/BP
CBNumber
CB4161628
Molecular Formula
C16H24ClNO4
Formula Weight
329.82
MOL File
105590-97-4.mol
More
Less

H-GLU(OBZL)-OTBU HCL Property

Melting point:
104-107°C
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO, Methanol
form 
Solid
color 
Off-White
InChI
InChI=1/C16H23NO4.ClH/c1-16(2,3)21-15(19)13(17)9-10-14(18)20-11-12-7-5-4-6-8-12;/h4-8,13H,9-11,17H2,1-3H3;1H/t13-;/s3
InChIKey
TWBZXIOAVCJDKR-PHCOUKOGNA-N
SMILES
C1(C=CC=CC=1)COC(=O)CC[C@H](N)C(=O)OC(C)(C)C.Cl |&1:12,r|
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
43
Safety Statements 
36/37
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
G598185
Product name
H-Glu(obzl)-otbuHydrochloride
Packaging
1g
Price
$75
Updated
2021/12/16
Activate Scientific
Product number
AS38878
Product name
(S)-5-Benzyl 1-tert-butyl 2-aminopentanedioate hydrochloride
Purity
97% ee
Packaging
1g
Price
$22
Updated
2021/12/16
AK Scientific
Product number
J92787
Product name
H-Glu(OBzl)-OtBuHCl
Packaging
5g
Price
$45
Updated
2021/12/16
Chem-Impex
Product number
11677
Product name
L-Glutamicacidγ-benzylesterα-tert-butylesterhydrochloride,99%(HPLC)
Purity
99%(HPLC)
Packaging
1G
Price
$50.4
Updated
2021/12/16
AK Scientific
Product number
X8766
Product name
H-Glu(OBzl)-OtBuHCl
Packaging
5g
Price
$61
Updated
2021/12/16
More
Less

H-GLU(OBZL)-OTBU HCL Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Uses

L-Glutamic Acid 1-(1,1-Dimethylethyl) 5-(Phenylmethyl) Ester Hydrochloride, is a versatile building block in the peptide chemistry. It can be used in the synthesis of series of dynamic peptides.

Uses

H-Glu(obzl)-otbu HCl

Synthesis

540-88-5

1676-73-9

105590-97-4

The general procedure for the synthesis of (S)-5-benzyl 1-tert-butyl 2-aminoglutarate hydrochloride from tert-butyl acetate and L-glutamic acid 5-benzyl ester was as follows: L-glutamic acid 5-benzyl ester (75 g) was dissolved in 750 ml of tert-butyl acetate, and the temperature of the reaction system was maintained at a temperature of less than 5°C by cooling the system with ice water from an external source. 26 ml of perchloric acid was added dropwise slowly in this condition, and after completion of addition, the temperature of the reaction system was raised to 25°C. The reaction was monitored by TLC until complete conversion of L-glutamic acid 5-benzyl ester. After completion of the addition, the temperature of the reaction system was raised to 25°C and the reaction was monitored by TLC until complete conversion of L-glutamic acid 5-benzyl ester. After the reaction was completed, the pH of the reaction solution was adjusted to 7-8 with aqueous sodium carbonate, and the aqueous and organic layers were separated. The organic layer was washed sequentially with water and brine and subsequently dried with anhydrous sodium sulfate. After filtration to remove the desiccant, tert-butyl acetate was removed by vacuum distillation at 50°C to obtain an oil. The oily substance was diluted with a small amount of ether and the pH was subsequently adjusted to 4-5 by addition of a pre-prepared ether hydrochloride solution, at which time the product precipitated. The precipitate was collected by filtration and dried to give 90 g of (S)-5-benzyl 1-tert-butyl 2-aminopentanedioate hydrochloride with a purity of 98.5% and a final yield of 80%.

References

[1] Patent: CN105541649, 2016, A. Location in patent: Paragraph 0014

H-GLU(OBZL)-OTBU HCL Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

H-GLU(OBZL)-OTBU HCL Suppliers

China 121 Germany 4 India 5 Japan 2 Switzerland 1 United Kingdom 2 United States 13 Global 148
Shanghai Kaipu New Biotechnology Co. , Ltd.
Tel
17821452002; 17821452002
Email
info@shanghaikaipuxin.com
Country
China
ProdList
35
Advantage
58
Shanghai Troedsson Technology Co., LTD
Tel
18117455885
Email
qihongchem@163.com
Country
China
ProdList
9092
Advantage
58
SICHUAN TONGSHENG BIOPHARMACEUTICAL CO., LTD
Tel
0838-2809458 13350585791
Email
pharm@biots.cn
Country
China
ProdList
589
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16077
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
3997
Advantage
55
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
10266
Advantage
58
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Tianjin Chempharmatech Co.,Ltd.
Tel
022-66211079 13212288319
Fax
qq1405432731
Email
sales@chempharmatech.com
Country
China
ProdList
918
Advantage
55
Shanghai SunSyn Pharmaceutical Co., Ltd.
Tel
18621020637 18621020637;
Email
sales@sunsynpharma.com
Country
China
ProdList
288
Advantage
55
Nanjing Credit Trading Co.,Ltd
Tel
025-52164950
Fax
025-86800069
Email
Googlexu_0114@sina.com
Country
China
ProdList
644
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9637
Advantage
58
Sichuan Ampebiochem Co., Ltd.
Tel
028-65294243 13981822079;18682730901
Email
sales@ampebiochem.com
Country
China
ProdList
1000
Advantage
58
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9906
Advantage
50
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Chengdu Chuangkecheng Biological Technology Co., Ltd.
Tel
028-028-0000000 13008177686
Fax
15928581901
Email
sales@ckcbiotech.com
Country
China
ProdList
904
Advantage
55
Shanghai GL Peptide Ltd.
Tel
+86-21-61263340; 17609490614 13764994101
Fax
021-61263399
Email
fisherwang@glschina.com
Country
China
ProdList
8258
Advantage
55
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Wuxi Asia Peptide Biotechnology Limited Company
Tel
0510-83583050 13771062561
Fax
0510-83583039
Email
willsun@peptide-search.com
Country
China
ProdList
6716
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805 15951641583
Fax
025-58361106-806
Email
zhao.xu@njpeptide.com
Country
China
ProdList
9979
Advantage
55
Shanghai Kangman Biological Technology Co., Ltd.
Tel
18800375331
Fax
021-50908862
Email
kangmansales@163.com
Country
China
ProdList
7570
Advantage
55
Sichuan jiayinglai technology CO.,LTD
Tel
028-028-88457210 18190964009
Fax
QQ3213375147
Email
3054240163@qq.com
Country
China
ProdList
2293
Advantage
55
Hangzhou Molcore Biopharmatech Co.,Ltd
Tel
400-711-5280 86-571-81025280
Fax
86-571-85806285
Email
sales@molcore.com
Country
China
ProdList
9967
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60
Aikon International Limited
Tel
025-58859352 18068836627
Fax
(5)02557626880
Email
dt3@aikonchem.com
Country
China
ProdList
15493
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
UHN Shanghai Research & Development Co., Ltd.
Tel
021-58958002 18930822973
Fax
021-58958618
Email
sales@uhnshanghai.com
Country
China
ProdList
1984
Advantage
58
Nanjing ChemLin Chemical Industry Co., Ltd.
Tel
025-83453353
Fax
025-83453353
Email
nj.chemlin@chemlin.com.cn
Country
CHINA
ProdList
853
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Cool Pharm, Ltd
Tel
021-58581007 18019463053
Fax
021-50966098
Email
sales@coolpharm.com
Country
China
ProdList
12878
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57422
Advantage
58
Kanghua (Shanghai) New Drug Development Co., Ltd.
Tel
021-61263370 18901917034
Email
xingli@glbiochem.com
Country
China
ProdList
5637
Advantage
58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19103
Advantage
58
Shanghai Jifeng Biotechnology Co., Ltd.
Tel
021-61263377 15023907684
Fax
021-61263399
Email
15800684150@163.com
Country
China
ProdList
8131
Advantage
58
Finetech Industry Limited
Tel
+86-27-8746-5837 +8619945049750
Fax
86 27 87772287
Email
info@finetechnology-ind.com
Country
China
ProdList
9629
Advantage
58
GL Biochem (Shanghai) Ltd.
Tel
+86-021-61263370 +86-18901917034
Country
CHINA
ProdList
3904
Advantage
58
Labnetwork lnc.
Tel
+86-27-50766799 +8618062016861
Email
contact@labnetwork.com
Country
China
ProdList
19987
Advantage
58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19908
Advantage
58
More
Less

View Lastest Price from H-GLU(OBZL)-OTBU HCL manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
L-Glu(Obzl)-Otbu.HCl 105590-97-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2024-03-26
Career Henan Chemical Co
Product
H-GLU(OBZL)-OTBU HCL 105590-97-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20kg
Release date
2018-08-22

105590-97-4, H-GLU(OBZL)-OTBU HCLRelated Search:

gamma-Benzyl L-glutamate Diethyl L-glutamate hydrochloride H-GLU(OET)-OH H-GLU(OALL)-OALL P-TOSYLATE H-GLU(OBZL)-OBZL HCL synthesis-021-HCl L-Glutamic acid 5-cyclohexyl ester L-Glutamic acid dibenzyl ester 4-toluenesulfonate H-Gln(Trt)-OH.H2O H-Glu(Gly-him)-OH ETHYL 4-AMINOBUTYRATE HYDROCHLORIDE L-Norvaline ethyl ester hydrochloride Glycine tert butyl ester hydrochloride L-Alanine Isopropyl Ester Hydrochloride L-(+)-Glutamic acid hydrochloride H-Glu-OMe H-GLY-OIPR HCL H-NVA-OME HCL

  • H-GLU(OBZL)-OTBU HCL
  • H-L-GLU(BZL)-OTBU HCL
  • H-L-GLU(OBZL)-OTBU HCL
  • L-GLUTAMIC ACID ALPHA-T-BUTYL-DELTA-BENZYL DIESTER HYDROCHLORIDE
  • L-GLUTAMIC ACID ALPHA-T-BUTYL-GAMMA-BENZYL-DIESTER HYDROCHLORIDE
  • L-GLUTAMIC ACID GAMMA-BENZYL ESTER ALPHA-T-BUTYL ESTER
  • GLUTAMIC ACID(OBZL)-OTBU HCL
  • 5-benzyl 1-tert-butyl (2S)-2-aminopentanedioate hydrochloride
  • GLUTAMIC ACID ALPHA-TERT-BUTYL-GAMMA-BENZYL DIESTER HYDROCHLORIDE
  • L-Glutamicacidγ-benzylesterα-tert·butylesterhydrochloride
  • H-Glu(Obzl)-Otbu hydrochloride
  • L-Glutamic acid alpha-t-butyl-gamma-benzyl ester hydrochloride
  • L-GLUTAMIC ACID-A-T-BUTYL-Y-BENZYL DIESTER HYDROCHLORIDE
  • L-GLUTAMIC ACID-.GAMMA.-BENZYLESTER .ALPHA.-TERT-BUTYLESTER HYDROCHLORIDE
  • L-Glutamicacid-benzylestera-tertutylesterhydrochloride
  • (S)-5-benzyl 1-tert-butyl 2-aminopentanedioate hydrochloride
  • L-Glutamic acid γ-benzyl ester α-tert·butyl est
  • Glu(Obzl)OtBu.HCl
  • H-Glu(OBzl)-OtBu·HCl L-GlutaMicacidγ-benzylesterα-tert·butylesterhydrochloride
  • H-L-Glu(Bzl)-OtBu Hydrochloride
  • L-Glu(OBzl)-OtBu·HCl
  • L-Glutamic acid γ-benzyl ester α-tert-butyl ester hydrochloride≥ 99% (HPLC)
  • 5-O-benzyl 1-O-tert-butyl (2S)-2-aminopentanedioate,hydrochloride
  • H-GLU(OBZL-OTBU HC
  • L-GlutaMic acid, 1-(1,1-diMethylethyl) 5-(phenylMethyl) ester, hydrochloride
  • hydrochloride of α-tert-butyl-γ-benzyl L-glutaMate
  • L-GlutaMic acid,1-(1,1-diMethylethyl) 5-(phenylMethyl) ester, hydrochloride (1:1)
  • L-Gluotbu-5-(phenylmethyl) ester hydrochloride
  • H-Glu(OBzl)-OtBu
  • H-GLU(OBZL)-OTBU HCL USP/EP/BP
  • L-Glutamic acid γ-benzyl ester α-tert-butyl ester hydrochloride
  • 5-O-benzyl 1-O-tert-butyl (2S)-2-aminopentanedioate
  • L-Glutamic Acid 5-Benzyl 1-tert-Butyl Ester Hydrochloride
  • L-Glutamic acid γ-benzyl ester α-tert-butyl ester hydrochloride, >98%
  • L-Glutamic acid γ-benzyl ester α-tert·butyl est
  • (S)-5-Benzyl 1-tert-butyl 2-aminopentanedioate HCl
  • 105590-97-4
  • 626-64-1
  • C16H24ClNO4