ChemicalBook > CAS DataBase List > 6-BROMO-IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID

6-BROMO-IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID

Product Name
6-BROMO-IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID
CAS No.
903129-78-2
Chemical Name
6-BROMO-IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID
Synonyms
6-broMoH-iMidazo[1;6-bromo-1H-imidazo[1,2-a]...;2-a]pyridine-8-carboxylic acid;6-bromo-8-imidazo[1,2-a]pyridinecarboxylic acid;6-BROMO-IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID;IMidazo[1,2-a]pyridine-8-carboxylic acid, 6-broMo-;6-bromo-1H-imidazo[1,2-a]pyridine-8-carboxylic acid
CBNumber
CB4166067
Molecular Formula
C8H5BrN2O2
Formula Weight
241.04
MOL File
Mol file
More
Less

6-BROMO-IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID Property

Density 
1.89±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
-1.37±0.41(Predicted)
Appearance
Off-white to light brown Solid
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
43
Safety Statements 
36/37
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FB148306
Product name
6-Bromoimidazo[1,2-a]pyridine-8-carboxylicacid
Packaging
50mg
Price
$78
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB148306
Product name
6-Bromoimidazo[1,2-a]pyridine-8-carboxylicacid
Packaging
100mg
Price
$136
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB148306
Product name
6-Bromoimidazo[1,2-a]pyridine-8-carboxylicacid
Packaging
250mg
Price
$270
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB148306
Product name
6-Bromoimidazo[1,2-a]pyridine-8-carboxylicacid
Packaging
500mg
Price
$470
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB148306
Product name
6-Bromoimidazo[1,2-a]pyridine-8-carboxylicacid
Packaging
1g
Price
$818.75
Updated
2021/12/16
More
Less

6-BROMO-IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis

97-97-2

52833-94-0

903129-78-2

GENERAL STEPS: 2-Amino-5-bromonicotinic acid (5.0 g, 23.04 mmol) and sodium acetate (3.78 g, 46.1 mmol) were dissolved in 100 mL of a 60% aqueous ethanol solution under stirring conditions. Subsequently, a solution of 2-chloro-1,1-dimethoxyethane (5.74 g, 46.1 mmol) in water (6 mL) was added to this solution and concentrated hydrochloric acid (1.0 mL) was added dropwise. The reaction mixture was heated to reflux for 2.5 hours. Upon completion of the reaction, the solvent was removed under reduced pressure and the residue was diluted with cold water and the pH adjusted to neutral (about 7) with saturated sodium bicarbonate solution. The reaction mixture was extracted with ethyl acetate (2 x 100 mL), the organic phases were combined, washed sequentially with water (2 x 100 mL) and brine (2 x 100 mL) and dried over anhydrous sodium sulfate. The crude product was purified by grinding with petroleum ether containing 2% ethyl acetate. 4.8 g of 6-bromoimidazo[1,2-a]pyridine-8-carboxylic acid was obtained in 86% yield. The product characterization data were as follows: 1H NMR (DMSO-d6, 300 MHz): δ 7.66 (d, 1H, J = 1.2 Hz, Ar), 7.79 (d, 1H, J = 1.5 Hz, Ar), 8.04 (s, 1H, Ar), 8.96 (d, 1H, J = 1.5 Hz, Ar); MS (ES+): m/e 242 (M + 1 ).

References

[1] Patent: WO2014/80241, 2014, A1. Location in patent: Page/Page column 41

6-BROMO-IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

6-BROMO-IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID Suppliers

China 68 Germany 1 India 1 United Kingdom 2 United States 15 Global 87
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
--
Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
More
Less

View Lastest Price from 6-BROMO-IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID manufacturers

Career Henan Chemical Co
Product
6-BROMO-IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID 903129-78-2
Price
US $0.10/KG
Min. Order
1KG
Purity
95%-99%
Supply Ability
1kg; 100kg; 1000kg
Release date
2019-12-25

903129-78-2, 6-BROMO-IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACIDRelated Search:

6-BROMOIMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE 6-Bromoimidazo[1,2-a]pyridin-8-ol 6-CHLORO-IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID 6-CHLOROIMIDAZO[1,2-A]PYRIDINE 6-broMo-8-hydroxy-iMidazo[1,2-a] pyridine hydrochloride IMidazo[1,2-a]pyridine-8-carboxylic acid, 3-iodo-, ethyl ester

  • 6-BROMO-IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID
  • 6-bromo-1H-imidazo[1,2-a]pyridine-8-carboxylic acid
  • 6-bromo-1H-imidazo[1,2-a]...
  • 2-a]pyridine-8-carboxylic acid
  • 6-broMoH-iMidazo[1
  • IMidazo[1,2-a]pyridine-8-carboxylic acid, 6-broMo-
  • 6-bromo-8-imidazo[1,2-a]pyridinecarboxylic acid
  • 903129-78-2