ChemicalBook > CAS DataBase List > 6-CHLOROIMIDAZO[1,2-A]PYRIDINE

6-CHLOROIMIDAZO[1,2-A]PYRIDINE

Product Name
6-CHLOROIMIDAZO[1,2-A]PYRIDINE
CAS No.
6188-25-6
Chemical Name
6-CHLOROIMIDAZO[1,2-A]PYRIDINE
Synonyms
6-CHLOROIMIDAZO[1,2-A]PYRIDINE;Imidazo[1,2-a]pyridine, 6-chloro-;6-Chloroimidazo[1,2-a]pyridine,97%
CBNumber
CB7166497
Molecular Formula
C7H5ClN2
Formula Weight
152.58
MOL File
6188-25-6.mol
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6-CHLOROIMIDAZO[1,2-A]PYRIDINE Property

Melting point:
85-87°C
Boiling point:
132°C/1.5mmHg(lit.)
Density 
1.35±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
pka
5.18±0.50(Predicted)
color 
Light yellow to Yellow to Orange
InChI
InChI=1S/C7H5ClN2/c8-6-1-2-7-9-3-4-10(7)5-6/h1-5H
InChIKey
XQEGYCZJSVFGEE-UHFFFAOYSA-N
SMILES
C12=NC=CN1C=C(Cl)C=C2
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
ADE001445
Product name
6-Chloroimidazo[1,2-a]pyridine
Purity
Aldrich
Packaging
1g
Price
$403
Updated
2025/07/31
TCI Chemical
Product number
C3370
Product name
6-Chloroimidazo[1,2-a]pyridine
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$35
Updated
2025/07/31
TCI Chemical
Product number
C3370
Product name
6-Chloroimidazo[1,2-a]pyridine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$121
Updated
2025/07/31
TRC
Product number
B419028
Product name
6-Chloroimidazo[1,2-a]pyridine
Packaging
100mg
Price
$75
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-5-A8
Product name
6-Chloroimidazo[1,2-a]pyridine
Packaging
10g
Price
$79
Updated
2021/12/16
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6-CHLOROIMIDAZO[1,2-A]PYRIDINE Chemical Properties,Usage,Production

Uses

6-Chlorimidazo[1,2-A]pyridine is a pyridine derivative and can be used as a pharmaceutical intermediate.

Synthesis

107-20-0

1072-98-6

6188-25-6

General procedure for the synthesis of 6-chloroimidazo[1,2-A]pyridine from chloroacetaldehyde and 2-amino-5-chloropyridine: 2-amino-5-chloropyridine (4.50 g, 35.00 mmol) and 2-chloroacetaldehyde (10.30 g, 52.50 mmol, 8.45 mL) in a solvent mixture of ethanol (50.00 mL) and water (10 mL) were reacted at 80 °C The reaction was stirred for 16 hours. Upon completion of the reaction, the reaction solution was concentrated to dryness and the resulting residue was diluted with water (100 mL) and subsequently extracted with ethyl acetate (150 mL x 2). The organic phases were combined, washed sequentially with water (50 mL × 2) and saturated saline (20 mL), dried over anhydrous sodium sulfate, filtered and concentrated to afford 6-chloroimidazo[1,2-A]pyridine (5.10 g, 33.43 mmol) as a solid product. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δH 8.18 (d, 1H), 7.65 (s, 1H), 7.59-7.50 (m, 2H), 7.12 (dd, 1H).

References

[1] Patent: WO2018/98500, 2018, A1. Location in patent: Page/Page column 80; 81

6-CHLOROIMIDAZO[1,2-A]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-CHLOROIMIDAZO[1,2-A]PYRIDINE Suppliers

Americas 1 China 116 Europe 1 Germany 2 Hungary 1 India 2 Japan 1 United Kingdom 3 United States 14 Global 141
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
ProdList
96815
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76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
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84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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81
Wuhan Chemwish Technology Co., Ltd
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86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
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Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
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62
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
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China
ProdList
14101
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59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
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China
ProdList
42934
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64
Jinan Trio PharmaTech Co., Ltd.
Tel
0531-88811783
Fax
+86 (531) 55696010 QQ 1762738062
Email
sales@trio-pharmatech.com
Country
China
ProdList
1856
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62
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
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Shanghai Sunway Pharmaceutical Technology Co., Ltd
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18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
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View Lastest Price from 6-CHLOROIMIDAZO[1,2-A]PYRIDINE manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
6-CHLOROIMIDAZO[1,2-A]PYRIDINE 6188-25-6
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-08-31
Career Henan Chemical Co
Product
6-CHLOROIMIDAZO[1,2-A]PYRIDINE 6188-25-6
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
1000KGS
Release date
2020-01-14

6188-25-6, 6-CHLOROIMIDAZO[1,2-A]PYRIDINERelated Search:

Ethyl 6-chloroimidazo[1,2-a]pyridine-2-carboxylate 6-Chloro-imidazo[1,2-a]pyrazine 6-Chloroimidazolo[1,2-A]Pyridin-2-Yl)Methanol 6-CHLOROIMIDAZO[1,2-A]PYRIMIDINE IMidazo[1,2-a]pyridine-3-carboxylic acid, 6-chloro-, Methyl ester 6-bromo-8-chloroimidazo[1,2-a]pyridine 4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE 7-CHLOROIMIDAZO[1,2-A]PYRIDINE 98% 3-chloroimidazo[1,2-a]pyridine-8-carboxylic acid 5-Chloroimidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester,Ethyl 5-chloroimidazo[1,2-a]pyridine-2-carboxylate 6-CHLOROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID,6-CHLOROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID, 95+% 2-TERT-BUTYL-6-CHLORO-IMIDAZO[1,2-A]PYRIDINE 2-(4-BROMOPHENYL)-6-CHLOROIMIDAZO[1,2-A]PYRIDINE 6-CHLORO-2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID 6-CHLORO-2-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER 6-CHLORO-2-(4-IODO-PHENYL)-IMIDAZO[1,2-A]PYRIDINE 6-CHLORO-2-(4-FLUOROPHENYL)IMIDAZO[1,2-A]PYRIDINE ETHYL 6-CHLORO-2-PHENYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLATE

  • 6-CHLOROIMIDAZO[1,2-A]PYRIDINE
  • Imidazo[1,2-a]pyridine, 6-chloro-
  • 6-Chloroimidazo[1,2-a]pyridine,97%
  • 6188-25-6